2′- C-Methylcytidine as a potent and selective inhibitor of the replication of foot-and-mouth disease virus

We report on the potent and selective in vitro antiviral activity of 2′- C-methylcytidine (2′- C-MetCyt) against foot-and-mouth disease virus (FMDV). FMDV belongs to the Picornaviridae and has the potential to cause devastating epidemics in livestock. The 50% and 90% effective concentrations (EC 50...

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