Talin2 is induced during striated muscle differentiation and is targeted to stable adhesion complexes in mature muscle

The cytoskeletal protein talin serves as an essential link between integrins and the actin cytoskeleton in several similar, but functionally distinct, adhesion complexes, including focal adhesions, costameres, and intercalated disks. Vertebrates contain two talin genes, TLN1 and TLN2, but the differ...

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Veröffentlicht in:	Cell motility and the cytoskeleton 2007-03, Vol.64 (3), p.157-173
Hauptverfasser:	Senetar, Melissa A., Moncman, Carole L., McCann, Richard O.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Adhesion Cell Differentiation Cells, Cultured costamere Cytoskeletal Proteins - genetics Cytoskeletal Proteins - immunology Cytoskeletal Proteins - metabolism focal adhesion Gene Expression Profiling Gene Expression Regulation Humans intercalated disk Mice Muscle Cells - cytology Muscle Cells - metabolism Muscle Development muscle differentiation Muscle, Skeletal - cytology Muscle, Skeletal - metabolism Myoblasts - cytology Myoblasts - metabolism Promoter Regions, Genetic - genetics Protein Isoforms - genetics Protein Isoforms - metabolism Protein Transport Rabbits Rats RNA, Messenger - genetics RNA, Messenger - metabolism talin Talin - genetics Talin - metabolism
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