Transient catabolic state with reduced IGF-I after antenatal glucocorticoids

Glucocorticoid (GC) administration before preterm birth reduces neonatal morbidity but may restrain growth. Here we explored the effect of antenatal GC on nutrient substrates [glucose, FFA, amino acids (AA)], and on IGF-I and IGF-binding protein-1 (IGFBP-1). We analyzed umbilical vein (UV) plasma ob...

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Veröffentlicht in:	Pediatric research 2007-09, Vol.62 (3), p.295-300
Hauptverfasser:	VERHAEGHE, Johan, VANSTAPEL, Florent, VAN BREE, Rita, VAN HERCK, Erik, COOPMANS, Willy
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acids - blood Biological and medical sciences Birth Weight Blood Glucose - metabolism Fatty Acids, Nonesterified - blood Female Fetal Blood - chemistry Fetus - drug effects Fetus - physiology General aspects Glucocorticoids - pharmacology Homeostasis Humans Infant, Newborn Insulin-Like Growth Factor Binding Protein 1 - metabolism Insulin-Like Growth Factor I - metabolism Male Medical sciences Pregnancy Premature Birth
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