Retention and Use of Breast Cancer Recurrence Risk Information from Genomic Tests: The Role of Health Literacy
Background: New genomic technology now allows physicians to provide women with individualized and highly accurate breast cancer recurrence risk estimates that are a key factor in adjuvant (after surgery) therapy decisions. Because these genomic tests are so new, little is known about how well patien...
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| Veröffentlicht in: | Cancer epidemiology, biomarkers & prevention biomarkers & prevention, 2007-02, Vol.16 (2), p.249-255 |
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| creator | LILLIE, Sarah E BREWER, Noel T O'NEILL, Suzanne C MORRILL, Edward F DEES, E. Claire CAREY, Lisa A RIMER, Barbara K |
| description | Background: New genomic technology now allows physicians to provide women with individualized and highly accurate breast cancer
recurrence risk estimates that are a key factor in adjuvant (after surgery) therapy decisions. Because these genomic tests
are so new, little is known about how well patients understand the tests and their results.
Method: We interviewed 163 stage I or II breast cancer patients at a routine follow-up appointment. We assessed their health
literacy (using the Rapid Estimate of Adult Learning in Medicine) as well as their knowledge of and attitudes towards a genomic
test that identifies risk of recurrence in hormone receptor–positive, node–negative breast cancer (the OncoType Dx Recurrence
Score).
Results: Women with lower health literacy recalled less of the information provided about the recurrence risk test than women
with higher health literacy. Health literacy was not related to the amount of additional information women desired. Women
with higher health literacy preferred to have a more active role in decisions about the test.
Implications: Health literacy may affect women's capacity to learn about the new genomic tests as well as their desire for
informed participation in their medical care. (Cancer Epidemiol Biomarkers Prev 2007;16(2):249–55) |
| doi_str_mv | 10.1158/1055-9965.EPI-06-0525 |
| format | Article |
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recurrence risk estimates that are a key factor in adjuvant (after surgery) therapy decisions. Because these genomic tests
are so new, little is known about how well patients understand the tests and their results.
Method: We interviewed 163 stage I or II breast cancer patients at a routine follow-up appointment. We assessed their health
literacy (using the Rapid Estimate of Adult Learning in Medicine) as well as their knowledge of and attitudes towards a genomic
test that identifies risk of recurrence in hormone receptor–positive, node–negative breast cancer (the OncoType Dx Recurrence
Score).
Results: Women with lower health literacy recalled less of the information provided about the recurrence risk test than women
with higher health literacy. Health literacy was not related to the amount of additional information women desired. Women
with higher health literacy preferred to have a more active role in decisions about the test.
Implications: Health literacy may affect women's capacity to learn about the new genomic tests as well as their desire for
informed participation in their medical care. (Cancer Epidemiol Biomarkers Prev 2007;16(2):249–55)</description><identifier>ISSN: 1055-9965</identifier><identifier>EISSN: 1538-7755</identifier><identifier>DOI: 10.1158/1055-9965.EPI-06-0525</identifier><identifier>PMID: 17267389</identifier><language>eng</language><publisher>Philadelphia, PA: American Association for Cancer Research</publisher><subject>Adult ; Aged ; Aged, 80 and over ; Biological and medical sciences ; breast cancer ; Breast Neoplasms - genetics ; Breast Neoplasms - pathology ; Breast Neoplasms - psychology ; Breast Neoplasms - therapy ; Chemotherapy, Adjuvant ; Decision Making ; Female ; Genomics ; Gynecology. Andrology. Obstetrics ; Health Knowledge, Attitudes, Practice ; health literacy ; Humans ; Mammary gland diseases ; Medical sciences ; Middle Aged ; Neoplasm Recurrence, Local ; Neoplasm Staging ; Patient Education as Topic ; Radiotherapy, Adjuvant ; recurrence risk ; Regression Analysis ; Surveys and Questionnaires ; Tumors</subject><ispartof>Cancer epidemiology, biomarkers & prevention, 2007-02, Vol.16 (2), p.249-255</ispartof><rights>2007 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c400t-1d4f24d29cbad0708aa9443d24c1737c688d155cb7cd0a9546ae4fe64072b29f3</citedby><cites>FETCH-LOGICAL-c400t-1d4f24d29cbad0708aa9443d24c1737c688d155cb7cd0a9546ae4fe64072b29f3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,3342,27903,27904</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=18838447$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/17267389$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>LILLIE, Sarah E</creatorcontrib><creatorcontrib>BREWER, Noel T</creatorcontrib><creatorcontrib>O'NEILL, Suzanne C</creatorcontrib><creatorcontrib>MORRILL, Edward F</creatorcontrib><creatorcontrib>DEES, E. Claire</creatorcontrib><creatorcontrib>CAREY, Lisa A</creatorcontrib><creatorcontrib>RIMER, Barbara K</creatorcontrib><title>Retention and Use of Breast Cancer Recurrence Risk Information from Genomic Tests: The Role of Health Literacy</title><title>Cancer epidemiology, biomarkers & prevention</title><addtitle>Cancer Epidemiol Biomarkers Prev</addtitle><description>Background: New genomic technology now allows physicians to provide women with individualized and highly accurate breast cancer
recurrence risk estimates that are a key factor in adjuvant (after surgery) therapy decisions. Because these genomic tests
are so new, little is known about how well patients understand the tests and their results.
Method: We interviewed 163 stage I or II breast cancer patients at a routine follow-up appointment. We assessed their health
literacy (using the Rapid Estimate of Adult Learning in Medicine) as well as their knowledge of and attitudes towards a genomic
test that identifies risk of recurrence in hormone receptor–positive, node–negative breast cancer (the OncoType Dx Recurrence
Score).
Results: Women with lower health literacy recalled less of the information provided about the recurrence risk test than women
with higher health literacy. Health literacy was not related to the amount of additional information women desired. Women
with higher health literacy preferred to have a more active role in decisions about the test.
Implications: Health literacy may affect women's capacity to learn about the new genomic tests as well as their desire for
informed participation in their medical care. (Cancer Epidemiol Biomarkers Prev 2007;16(2):249–55)</description><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Biological and medical sciences</subject><subject>breast cancer</subject><subject>Breast Neoplasms - genetics</subject><subject>Breast Neoplasms - pathology</subject><subject>Breast Neoplasms - psychology</subject><subject>Breast Neoplasms - therapy</subject><subject>Chemotherapy, Adjuvant</subject><subject>Decision Making</subject><subject>Female</subject><subject>Genomics</subject><subject>Gynecology. Andrology. Obstetrics</subject><subject>Health Knowledge, Attitudes, Practice</subject><subject>health literacy</subject><subject>Humans</subject><subject>Mammary gland diseases</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Neoplasm Recurrence, Local</subject><subject>Neoplasm Staging</subject><subject>Patient Education as Topic</subject><subject>Radiotherapy, Adjuvant</subject><subject>recurrence risk</subject><subject>Regression Analysis</subject><subject>Surveys and Questionnaires</subject><subject>Tumors</subject><issn>1055-9965</issn><issn>1538-7755</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2007</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkctuFDEQRS0EIg_4BJA3kFUH2-0nuzAKyUgjgUaTteVxl2lDdzvYPUL5ezwPlCUr1-LcKusehN5Rck2p0J8oEaIxRorr2-_LhsiGCCZeoHMqWt0oJcTLOv9jztBFKT8JIcoI8RqdUcWkarU5R9MaZpjmmCbspg4_FMAp4C8ZXJnxwk0eMl6D3-UMdcbrWH7h5RRSHt0hFHIa8R1MaYweb6DM5TPe9BVMw2HTPbhh7vEqzpCdf3qDXgU3FHh7ei_Rw9fbzeK-WX27Wy5uVo3nhMwN7XhgvGPGb11HFNHOGc7bjnFPVau81LqjQvit8h1xRnDpgAeQnCi2ZSa0l-jjce9jTr939Vt2jMXDMLgJ0q5YaQiRmrD_gtQIWU_rCooj6HMqJUOwjzmOLj9ZSuzeiN23bfdt22rEEmn3Rmru_enAbjtC95w6KajAhxPgindDyLX0WJ45rVvNuarc1ZHr44_-T8xg_UFPhgIu-95SaZll3LR_AbOYoYE</recordid><startdate>20070201</startdate><enddate>20070201</enddate><creator>LILLIE, Sarah E</creator><creator>BREWER, Noel T</creator><creator>O'NEILL, Suzanne C</creator><creator>MORRILL, Edward F</creator><creator>DEES, E. Claire</creator><creator>CAREY, Lisa A</creator><creator>RIMER, Barbara K</creator><general>American Association for Cancer Research</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7U1</scope><scope>7U2</scope><scope>8FD</scope><scope>C1K</scope><scope>FR3</scope><scope>P64</scope><scope>RC3</scope><scope>7X8</scope></search><sort><creationdate>20070201</creationdate><title>Retention and Use of Breast Cancer Recurrence Risk Information from Genomic Tests: The Role of Health Literacy</title><author>LILLIE, Sarah E ; BREWER, Noel T ; O'NEILL, Suzanne C ; MORRILL, Edward F ; DEES, E. Claire ; CAREY, Lisa A ; RIMER, Barbara K</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c400t-1d4f24d29cbad0708aa9443d24c1737c688d155cb7cd0a9546ae4fe64072b29f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2007</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Biological and medical sciences</topic><topic>breast cancer</topic><topic>Breast Neoplasms - genetics</topic><topic>Breast Neoplasms - pathology</topic><topic>Breast Neoplasms - psychology</topic><topic>Breast Neoplasms - therapy</topic><topic>Chemotherapy, Adjuvant</topic><topic>Decision Making</topic><topic>Female</topic><topic>Genomics</topic><topic>Gynecology. Andrology. Obstetrics</topic><topic>Health Knowledge, Attitudes, Practice</topic><topic>health literacy</topic><topic>Humans</topic><topic>Mammary gland diseases</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Neoplasm Recurrence, Local</topic><topic>Neoplasm Staging</topic><topic>Patient Education as Topic</topic><topic>Radiotherapy, Adjuvant</topic><topic>recurrence risk</topic><topic>Regression Analysis</topic><topic>Surveys and Questionnaires</topic><topic>Tumors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>LILLIE, Sarah E</creatorcontrib><creatorcontrib>BREWER, Noel T</creatorcontrib><creatorcontrib>O'NEILL, Suzanne C</creatorcontrib><creatorcontrib>MORRILL, Edward F</creatorcontrib><creatorcontrib>DEES, E. Claire</creatorcontrib><creatorcontrib>CAREY, Lisa A</creatorcontrib><creatorcontrib>RIMER, Barbara K</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Risk Abstracts</collection><collection>Safety Science and Risk</collection><collection>Technology Research Database</collection><collection>Environmental Sciences and Pollution Management</collection><collection>Engineering Research Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Cancer epidemiology, biomarkers & prevention</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>LILLIE, Sarah E</au><au>BREWER, Noel T</au><au>O'NEILL, Suzanne C</au><au>MORRILL, Edward F</au><au>DEES, E. Claire</au><au>CAREY, Lisa A</au><au>RIMER, Barbara K</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Retention and Use of Breast Cancer Recurrence Risk Information from Genomic Tests: The Role of Health Literacy</atitle><jtitle>Cancer epidemiology, biomarkers & prevention</jtitle><addtitle>Cancer Epidemiol Biomarkers Prev</addtitle><date>2007-02-01</date><risdate>2007</risdate><volume>16</volume><issue>2</issue><spage>249</spage><epage>255</epage><pages>249-255</pages><issn>1055-9965</issn><eissn>1538-7755</eissn><abstract>Background: New genomic technology now allows physicians to provide women with individualized and highly accurate breast cancer
recurrence risk estimates that are a key factor in adjuvant (after surgery) therapy decisions. Because these genomic tests
are so new, little is known about how well patients understand the tests and their results.
Method: We interviewed 163 stage I or II breast cancer patients at a routine follow-up appointment. We assessed their health
literacy (using the Rapid Estimate of Adult Learning in Medicine) as well as their knowledge of and attitudes towards a genomic
test that identifies risk of recurrence in hormone receptor–positive, node–negative breast cancer (the OncoType Dx Recurrence
Score).
Results: Women with lower health literacy recalled less of the information provided about the recurrence risk test than women
with higher health literacy. Health literacy was not related to the amount of additional information women desired. Women
with higher health literacy preferred to have a more active role in decisions about the test.
Implications: Health literacy may affect women's capacity to learn about the new genomic tests as well as their desire for
informed participation in their medical care. (Cancer Epidemiol Biomarkers Prev 2007;16(2):249–55)</abstract><cop>Philadelphia, PA</cop><pub>American Association for Cancer Research</pub><pmid>17267389</pmid><doi>10.1158/1055-9965.EPI-06-0525</doi><tpages>7</tpages></addata></record> |
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| issn | 1055-9965 1538-7755 |
| language | eng |
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| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; American Association for Cancer Research |
| subjects | Adult Aged Aged, 80 and over Biological and medical sciences breast cancer Breast Neoplasms - genetics Breast Neoplasms - pathology Breast Neoplasms - psychology Breast Neoplasms - therapy Chemotherapy, Adjuvant Decision Making Female Genomics Gynecology. Andrology. Obstetrics Health Knowledge, Attitudes, Practice health literacy Humans Mammary gland diseases Medical sciences Middle Aged Neoplasm Recurrence, Local Neoplasm Staging Patient Education as Topic Radiotherapy, Adjuvant recurrence risk Regression Analysis Surveys and Questionnaires Tumors |
| title | Retention and Use of Breast Cancer Recurrence Risk Information from Genomic Tests: The Role of Health Literacy |
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