Vlgr1 is required for proper stereocilia maturation of cochlear hair cells

Very large G‐protein coupled receptor (Vlgr1b) is the largest known G‐protein coupled receptor. Its function is unknown, although mice with deletion of Vlgr1 (Vlgr1b together with other splicing variants, Vlgr1c, Vlgr1d and Vlgr1e) are known to exhibit audiogenic seizure susceptibility and VLGR1 is...

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Veröffentlicht in:	Genes to cells : devoted to molecular & cellular mechanisms 2007-02, Vol.12 (2), p.235-250
Hauptverfasser:	Yagi, Hideshi, Tokano, Hisashi, Maeda, Mitsuyo, Takabayashi, Tetsuji, Nagano, Takashi, Kiyama, Hiroshi, Fujieda, Shigeharu, Kitamura, Ken, Sato, Makoto
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cilia - physiology Hair Cells, Auditory - physiology Hair Cells, Auditory - ultrastructure Mice Mice, Knockout Microscopy, Electron, Scanning Microscopy, Immunoelectron Receptors, G-Protein-Coupled - genetics Receptors, G-Protein-Coupled - physiology
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