Mass spectroscopic characterisation of oligomeric proanthocyanidins derived from an extract of Pelargonium sidoides roots (EPs ® 7630) and pharmacological screening in CNS models

Chromatographic fractionation of proanthocyanidin oligomers from an aqueous ethanolic extract of Pelargonium sidoides roots (EPs ® 7630) gave a diverse set of epigallo- and gallocatechin based oligomers, which are connected by A and B-type bonds. Additionally, two series of monosubstituted oligomers...

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Veröffentlicht in:	Phytomedicine (Stuttgart) 2007-02, Vol.14 (2-3), p.32-39
Hauptverfasser:	Schotz, Karl, Noldner, Michael
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Oral Aminoconjugates Animals Behavior, Animal - drug effects Behavioural Activities Central Nervous System - drug effects Central nervous system agents Chemical properties Chromatography Ethnopharmacology Geraniums Male Mass Spectrometry Mass spectroscopy Medicinal plants Mice Observations Oligomers Pelargonium Pelargonium sidoides Phytotherapy Plant Extracts - administration & dosage Plant Extracts - chemistry Plant Extracts - pharmacology Plant Extracts - therapeutic use Plant Roots Proanthocyanidins Proanthocyanidins - chemistry
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