Epidermal Growth Factor Receptor Protein Expression and Gene Amplification in Small Cell Carcinoma of the Urinary Bladder

Purpose: Small cell carcinoma of the urinary bladder is a highly aggressive malignancy with an average life expectancy of only a few months. Epidermal growth factor receptor (EGFR) has been implicated in the pathogenesis and progression of many malignancies. This study was done to investigate EGFR p...

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Veröffentlicht in:	Clinical cancer research 2007-02, Vol.13 (3), p.953-957
Hauptverfasser:	Wang, Xiaoyan, Zhang, Shaobo, MacLennan, Gregory T, Eble, John N, Lopez-Beltran, Antonio, Yang, Ximing J, Pan, Chong-Xian, Zhou, Honghong, Montironi, Rodolfo, Cheng, Liang
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Antineoplastic agents Biological and medical sciences Biomarkers, Tumor Carcinoma, Small Cell - genetics Carcinoma, Small Cell - metabolism epidermal growth factor receptor (EGFR) Female Gene Amplification Gene Expression Regulation, Neoplastic Humans Immunohistochemistry In Situ Hybridization, Fluorescence Lymphatic Metastasis Male Medical sciences Middle Aged Neoplasm Invasiveness Pharmacology. Drug treatments prognosis Receptor, Epidermal Growth Factor - biosynthesis small cell carcinoma survival urinary bladder Urinary Bladder Neoplasms - genetics Urinary Bladder Neoplasms - metabolism
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