p38 MAP kinase regulation of oligodendrocyte differentiation with CREB as a potential target

Despite a substantial understanding of the factors regulating oligodendrocyte differentiation, the signaling mechanisms involved in this process are not well-understood. This study elaborates on the findings (Bhat NR, Zhang P (1997) FASEB J 11:A925; Baron W, Metz B, Bansal R, Hoekstra D, de Vries H...

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Veröffentlicht in:	Neurochemical research 2007-02, Vol.32 (2), p.293-302
Hauptverfasser:	Bhat, Narayan R, Zhang, Peisheng, Mohanty, Sangeeta B
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Differentiation - drug effects Cells, Cultured Colforsin - pharmacology Cyclic AMP Response Element-Binding Protein - physiology Enzyme Activation Imidazoles - pharmacology Myelin Basic Protein - biosynthesis Myelin Proteolipid Protein - biosynthesis Myelin-Associated Glycoprotein - biosynthesis Oligodendroglia - cytology Oligodendroglia - drug effects p38 Mitogen-Activated Protein Kinases - antagonists & inhibitors p38 Mitogen-Activated Protein Kinases - physiology Phosphorylation - drug effects Pyridines - pharmacology Rats RNA, Messenger - antagonists & inhibitors
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