Influence of scale-up on the abrasion of tablets in a pan coater

The purpose of this study was to examine the influence of batch size during scale-up on the abrasion and edge splitting of flat faced lactose tablets. The weight loss of white tracer tablets in a batch of blue coated tablets was investigated in a laboratory scale pan coater and a pilot scale pan coa...

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Veröffentlicht in:	European journal of pharmaceutics and biopharmaceutics 2006-11, Vol.64 (3), p.388-392
Hauptverfasser:	Mueller, Ronny, Kleinebudde, Peter
Format:	Artikel
Sprache:	eng
Schlagworte:	Abrasion Biological and medical sciences Bohle Film Coater Chemistry, Pharmaceutical Film coating General pharmacology Hardness Lactose - chemistry Medical sciences Pan speed Pharmaceutical technology. Pharmaceutical industry Pharmacology. Drug treatments Polyvinyls - chemistry Scale-up Tablets, Enteric-Coated - standards Technology, Pharmaceutical - methods Time Factors
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