Suprabasal overexpression of Beta-1 integrin is induced by bovine papillomavirus type 1

In a normal stratified squamous epithelium, β1-integrin is expressed in basal epithelial cells. In BPV-induced fibropapillomas β1-integrin is overexpressed and aberrantly localized, with uniform expression in the lower spinous layer, and sporadic expression within the mid-spinous region that co-loca...

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Veröffentlicht in:	Virology (New York, N.Y.) N.Y.), 2006-11, Vol.355 (1), p.102-114
Hauptverfasser:	Cooper, Brooke, Brimer, Nicole, Stoler, Mark, Vande Pol, Scott B.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Blotting, Western Bovine papillomavirus Bovine papillomavirus 1 - physiology Cattle cattle diseases Cell Line cultured cells DNA - biosynthesis epidermal growth factor Epithelium - pathology Epithelium - virology Gene Expression Regulation gene overexpression glycoproteins Histocytochemistry Humans In Situ Hybridization Integrin Integrin beta1 - biosynthesis integrins Keratinocytes - virology MAP Kinase Kinase Kinase 3 - biosynthesis Microscopy, Fluorescence Oncogene Proteins, Viral - biosynthesis Oncogene Proteins, Viral - physiology Oncoprotein Papilloma - immunology Papilloma - pathology Papilloma - virology Papillomavirus Infections - immunology Papillomavirus Infections - virology Psoriasis RNA - biosynthesis RNA - genetics transcription (genetics) viral envelope proteins viral proteins Virus Replication
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