Enantioselective Synthesis of Planar-Chiral Metacyclophanes through Rhodium-Catalyzed Alkyne Cyclotrimerization

Enantioselective Synthesis of Planar-Chiral Metacyclophanes through Rhodium-Catalyzed Alkyne Cyclotrimerization

We have achieved the first catalytic enantioselective synthesis of planar-chiral metacyclophanes by means of cationic rhodium(I)/(R)-H8-BINAP complex-catalyzed alkyne cyclotrimerization. This reaction represents a versatile new method for the preparation of planar-chiral [7]−[10]metacyclophanes.

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Journal of the American Chemical Society 2007-02, Vol.129 (6), p.1522-1523
Hauptverfasser: Tanaka, Ken, Sagae, Hiromi, Toyoda, Kazuki, Noguchi, Keiichi, Hirano, Masao
Format: Artikel
Sprache:eng
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:We have achieved the first catalytic enantioselective synthesis of planar-chiral metacyclophanes by means of cationic rhodium(I)/(R)-H8-BINAP complex-catalyzed alkyne cyclotrimerization. This reaction represents a versatile new method for the preparation of planar-chiral [7]−[10]metacyclophanes.
ISSN:0002-7863
1520-5126
DOI:10.1021/ja0679127