Influence of β-Adrenoceptor Blockade on the Myocardial Accumulation of Fatty Acid Tracer and Its Intracellular Metabolism in the Heart After Ischemia-Reperfusion Injury

Background Increases in sympathetic nerve activity during ischemia may increase intracellular fatty acid (FA) accumulation via enhanced FA uptake and inhibition of β-oxidation. Therefore, the beneficial effects of β-adrenoceptor blockade on myocardial ischemic injury might result from the suppressio...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Circulation Journal 2006, Vol.70(11), pp.1509-1514
Hauptverfasser:	Igarashi, Norio, Nozawa, Takashi, Fujii, Nozomu, Suzuki, Takayuki, Matsuki, Akira, Nakadate, Teruo, Igawa, Akihiko, Inoue, Hiroshi
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenergic beta-Antagonists - pharmacology Animals Autoradiography - methods Carbazoles - pharmacology Carvedilol Fatty acids Fatty Acids - metabolism Iodobenzenes - metabolism Ischemia-reperfusion Male Metabolism Myocardial Ischemia - physiopathology Myocardium Myocardium - metabolism Oxidation-Reduction Propanolamines - pharmacology Propranolol - pharmacology Radiotracers Rats Rats, Wistar Receptors, Adrenergic, beta - drug effects Reperfusion Injury - metabolism β-adrenoceptor blockade
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!