Effect of selenium supplementation on biochemical markers and outcome in critically ill patients

Summary Background & Aims This study aimed to assess the effect of high dose selenium (Se) supplementation on Se status in blood, oxidative stress, thyroid function and possible effects on requirement for renal replacement therapy (RRT) in severely septic patients admitted to the intensive care...

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Veröffentlicht in:	Clinical nutrition (Edinburgh, Scotland) Scotland), 2007-02, Vol.26 (1), p.41-50
Hauptverfasser:	Mishra, Vinita, Baines, Malcolm, Elizabeth Perry, Sara, Jeremy McLaughlin, Paul, Carson, Jeff, Wenstone, Richard, Shenkin, Alan
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Antioxidants - metabolism Antioxidants - therapeutic use Biological and medical sciences Biomarkers - blood C-Reactive Protein - analysis Critical Illness - therapy Dietary Supplements Dose-Response Relationship, Drug Double-Blind Method Erythrocytes - enzymology F2 isoprostanes F2IsoP Female Gastroenterology and Hepatology Glutathione peroxidase Glutathione Peroxidase - metabolism GSH-Px Humans Intensive care unit (ICU) Intensive Care Units Kidney - drug effects Kidney - physiology Male Medical sciences Metabolic diseases Multiple Organ Failure - epidemiology Nutritional Requirements Oxidative Stress - drug effects Prospective Studies Renal Replacement Therapy Selenium - blood Selenium - therapeutic use Sepsis Sepsis - blood Sepsis - therapy Severity of Illness Index SIRS Systemic inflammatory response syndrome Thyroid Gland - drug effects Thyroid Gland - physiology Treatment Outcome
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