Hepatitis B in children with cancer
Cancer patients can be asymptomatic carriers of the hepatitis B virus (HBV), which can be reactivated by chemotherapy. Our aim was to identify the serological markers of HBV in children with cancer who were asymptomatic carriers of the virus. Fifty two (52) children with cancer treated at the Maraca...
Gespeichert in:
| Veröffentlicht in: | Revista de gastroenterología del Perú 2006-07, Vol.26 (3), p.259-264 |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artikel |
| Sprache: | spa |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 264 |
|---|---|
| container_issue | 3 |
| container_start_page | 259 |
| container_title | Revista de gastroenterología del Perú |
| container_volume | 26 |
| creator | Espinoza Holguin, Maurin Arteaga-Vizcaíno, Melvis Porto, Leticia Montilva, Rosario Atencio, Ricardo Diana, Callejas Ferrer O, Olmedo |
| description | Cancer patients can be asymptomatic carriers of the hepatitis B virus (HBV), which can be reactivated by chemotherapy. Our aim was to identify the serological markers of HBV in children with cancer who were asymptomatic carriers of the virus. Fifty two (52) children with cancer treated at the Maracaibo University Hospital in Venezuela were studied, 28 of these children (53.8%) were HBV positive, despite no clinical or biochemical signs or symptoms of hepatitis. The type of serological markers present in each of these children.were investigated. We found 7 cases (25%) with hepatitis B surface antigen (HBsAg) and 2 (7.1%) with anticore as the only markers. Multiple markers were found in the other children: 9 (32.1%) HBsAg and anticore; 7 (25%) HBsAg, e-antigen (HBeAg) and anticore; 3 (10.7%) HBsAg, HBeAg antibody and anticore. In total, of the 28 positive children 20 (71.4%) showed positive anticore and of these 4 (20%) were of the IgM type. Our results show a high level of positivity for HBV in the children with cancer studied. In spite of being asymptomatic carriers of the HBV, it is noticeable the presence of serological markers for acute disease. We recommend testing for HBV serological markers before starting chemotherapy. Should the test results be negative, vaccination is indicated and should they be positive, specialized care is indicated. |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_proquest_miscellaneous_68984017</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>68984017</sourcerecordid><originalsourceid>FETCH-LOGICAL-p541-a183f6c2652a2ae931928b826b3d5d74cda4f276b37b13bc4166eace9e8c0c973</originalsourceid><addsrcrecordid>eNo1j81KAzEYRbNQbK19BQkI7gaSLz-TLLWoFQpuuh_y8w1NmZmOyQzi26vYrg4XDhfOFVlyBlApDnZBbks5MiaZBH1DFrxmShjgS_KwxdFNaUqFPtM00HBIXcw40K80HWhwQ8B8R65b1xVcn7ki-9eX_WZb7T7e3jdPu2pUkleOG9HqAFqBA4dWcAvGG9BeRBVrGaKTLdS_s_Zc-CC51ugCWjSBBVuLFXn8vx3z6XPGMjV9KgG7zg14mkujjTWS8T_x_izOvsfYjDn1Ln83lyrxA2A4Rd0</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>68984017</pqid></control><display><type>article</type><title>Hepatitis B in children with cancer</title><source>MEDLINE</source><source>EZB-FREE-00999 freely available EZB journals</source><creator>Espinoza Holguin, Maurin ; Arteaga-Vizcaíno, Melvis ; Porto, Leticia ; Montilva, Rosario ; Atencio, Ricardo ; Diana, Callejas ; Ferrer O, Olmedo</creator><creatorcontrib>Espinoza Holguin, Maurin ; Arteaga-Vizcaíno, Melvis ; Porto, Leticia ; Montilva, Rosario ; Atencio, Ricardo ; Diana, Callejas ; Ferrer O, Olmedo</creatorcontrib><description>Cancer patients can be asymptomatic carriers of the hepatitis B virus (HBV), which can be reactivated by chemotherapy. Our aim was to identify the serological markers of HBV in children with cancer who were asymptomatic carriers of the virus. Fifty two (52) children with cancer treated at the Maracaibo University Hospital in Venezuela were studied, 28 of these children (53.8%) were HBV positive, despite no clinical or biochemical signs or symptoms of hepatitis. The type of serological markers present in each of these children.were investigated. We found 7 cases (25%) with hepatitis B surface antigen (HBsAg) and 2 (7.1%) with anticore as the only markers. Multiple markers were found in the other children: 9 (32.1%) HBsAg and anticore; 7 (25%) HBsAg, e-antigen (HBeAg) and anticore; 3 (10.7%) HBsAg, HBeAg antibody and anticore. In total, of the 28 positive children 20 (71.4%) showed positive anticore and of these 4 (20%) were of the IgM type. Our results show a high level of positivity for HBV in the children with cancer studied. In spite of being asymptomatic carriers of the HBV, it is noticeable the presence of serological markers for acute disease. We recommend testing for HBV serological markers before starting chemotherapy. Should the test results be negative, vaccination is indicated and should they be positive, specialized care is indicated.</description><identifier>ISSN: 1022-5129</identifier><identifier>PMID: 17053821</identifier><language>spa</language><publisher>Peru</publisher><subject>Adolescent ; Carrier State - epidemiology ; Child ; Child, Preschool ; Female ; Hepatitis B - blood ; Hepatitis B - complications ; Hepatitis B - epidemiology ; Hepatitis B Antigens - blood ; Hepatitis B Surface Antigens - blood ; Hepatitis B virus - immunology ; Hepatitis B virus - isolation & purification ; Humans ; Liver Function Tests ; Male ; Neoplasms - blood ; Neoplasms - complications ; Prevalence ; Seroepidemiologic Studies ; Venezuela - epidemiology</subject><ispartof>Revista de gastroenterología del Perú, 2006-07, Vol.26 (3), p.259-264</ispartof><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/17053821$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Espinoza Holguin, Maurin</creatorcontrib><creatorcontrib>Arteaga-Vizcaíno, Melvis</creatorcontrib><creatorcontrib>Porto, Leticia</creatorcontrib><creatorcontrib>Montilva, Rosario</creatorcontrib><creatorcontrib>Atencio, Ricardo</creatorcontrib><creatorcontrib>Diana, Callejas</creatorcontrib><creatorcontrib>Ferrer O, Olmedo</creatorcontrib><title>Hepatitis B in children with cancer</title><title>Revista de gastroenterología del Perú</title><addtitle>Rev Gastroenterol Peru</addtitle><description>Cancer patients can be asymptomatic carriers of the hepatitis B virus (HBV), which can be reactivated by chemotherapy. Our aim was to identify the serological markers of HBV in children with cancer who were asymptomatic carriers of the virus. Fifty two (52) children with cancer treated at the Maracaibo University Hospital in Venezuela were studied, 28 of these children (53.8%) were HBV positive, despite no clinical or biochemical signs or symptoms of hepatitis. The type of serological markers present in each of these children.were investigated. We found 7 cases (25%) with hepatitis B surface antigen (HBsAg) and 2 (7.1%) with anticore as the only markers. Multiple markers were found in the other children: 9 (32.1%) HBsAg and anticore; 7 (25%) HBsAg, e-antigen (HBeAg) and anticore; 3 (10.7%) HBsAg, HBeAg antibody and anticore. In total, of the 28 positive children 20 (71.4%) showed positive anticore and of these 4 (20%) were of the IgM type. Our results show a high level of positivity for HBV in the children with cancer studied. In spite of being asymptomatic carriers of the HBV, it is noticeable the presence of serological markers for acute disease. We recommend testing for HBV serological markers before starting chemotherapy. Should the test results be negative, vaccination is indicated and should they be positive, specialized care is indicated.</description><subject>Adolescent</subject><subject>Carrier State - epidemiology</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>Female</subject><subject>Hepatitis B - blood</subject><subject>Hepatitis B - complications</subject><subject>Hepatitis B - epidemiology</subject><subject>Hepatitis B Antigens - blood</subject><subject>Hepatitis B Surface Antigens - blood</subject><subject>Hepatitis B virus - immunology</subject><subject>Hepatitis B virus - isolation & purification</subject><subject>Humans</subject><subject>Liver Function Tests</subject><subject>Male</subject><subject>Neoplasms - blood</subject><subject>Neoplasms - complications</subject><subject>Prevalence</subject><subject>Seroepidemiologic Studies</subject><subject>Venezuela - epidemiology</subject><issn>1022-5129</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2006</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo1j81KAzEYRbNQbK19BQkI7gaSLz-TLLWoFQpuuh_y8w1NmZmOyQzi26vYrg4XDhfOFVlyBlApDnZBbks5MiaZBH1DFrxmShjgS_KwxdFNaUqFPtM00HBIXcw40K80HWhwQ8B8R65b1xVcn7ki-9eX_WZb7T7e3jdPu2pUkleOG9HqAFqBA4dWcAvGG9BeRBVrGaKTLdS_s_Zc-CC51ugCWjSBBVuLFXn8vx3z6XPGMjV9KgG7zg14mkujjTWS8T_x_izOvsfYjDn1Ln83lyrxA2A4Rd0</recordid><startdate>200607</startdate><enddate>200607</enddate><creator>Espinoza Holguin, Maurin</creator><creator>Arteaga-Vizcaíno, Melvis</creator><creator>Porto, Leticia</creator><creator>Montilva, Rosario</creator><creator>Atencio, Ricardo</creator><creator>Diana, Callejas</creator><creator>Ferrer O, Olmedo</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>200607</creationdate><title>Hepatitis B in children with cancer</title><author>Espinoza Holguin, Maurin ; Arteaga-Vizcaíno, Melvis ; Porto, Leticia ; Montilva, Rosario ; Atencio, Ricardo ; Diana, Callejas ; Ferrer O, Olmedo</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p541-a183f6c2652a2ae931928b826b3d5d74cda4f276b37b13bc4166eace9e8c0c973</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>spa</language><creationdate>2006</creationdate><topic>Adolescent</topic><topic>Carrier State - epidemiology</topic><topic>Child</topic><topic>Child, Preschool</topic><topic>Female</topic><topic>Hepatitis B - blood</topic><topic>Hepatitis B - complications</topic><topic>Hepatitis B - epidemiology</topic><topic>Hepatitis B Antigens - blood</topic><topic>Hepatitis B Surface Antigens - blood</topic><topic>Hepatitis B virus - immunology</topic><topic>Hepatitis B virus - isolation & purification</topic><topic>Humans</topic><topic>Liver Function Tests</topic><topic>Male</topic><topic>Neoplasms - blood</topic><topic>Neoplasms - complications</topic><topic>Prevalence</topic><topic>Seroepidemiologic Studies</topic><topic>Venezuela - epidemiology</topic><toplevel>online_resources</toplevel><creatorcontrib>Espinoza Holguin, Maurin</creatorcontrib><creatorcontrib>Arteaga-Vizcaíno, Melvis</creatorcontrib><creatorcontrib>Porto, Leticia</creatorcontrib><creatorcontrib>Montilva, Rosario</creatorcontrib><creatorcontrib>Atencio, Ricardo</creatorcontrib><creatorcontrib>Diana, Callejas</creatorcontrib><creatorcontrib>Ferrer O, Olmedo</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Revista de gastroenterología del Perú</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Espinoza Holguin, Maurin</au><au>Arteaga-Vizcaíno, Melvis</au><au>Porto, Leticia</au><au>Montilva, Rosario</au><au>Atencio, Ricardo</au><au>Diana, Callejas</au><au>Ferrer O, Olmedo</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Hepatitis B in children with cancer</atitle><jtitle>Revista de gastroenterología del Perú</jtitle><addtitle>Rev Gastroenterol Peru</addtitle><date>2006-07</date><risdate>2006</risdate><volume>26</volume><issue>3</issue><spage>259</spage><epage>264</epage><pages>259-264</pages><issn>1022-5129</issn><abstract>Cancer patients can be asymptomatic carriers of the hepatitis B virus (HBV), which can be reactivated by chemotherapy. Our aim was to identify the serological markers of HBV in children with cancer who were asymptomatic carriers of the virus. Fifty two (52) children with cancer treated at the Maracaibo University Hospital in Venezuela were studied, 28 of these children (53.8%) were HBV positive, despite no clinical or biochemical signs or symptoms of hepatitis. The type of serological markers present in each of these children.were investigated. We found 7 cases (25%) with hepatitis B surface antigen (HBsAg) and 2 (7.1%) with anticore as the only markers. Multiple markers were found in the other children: 9 (32.1%) HBsAg and anticore; 7 (25%) HBsAg, e-antigen (HBeAg) and anticore; 3 (10.7%) HBsAg, HBeAg antibody and anticore. In total, of the 28 positive children 20 (71.4%) showed positive anticore and of these 4 (20%) were of the IgM type. Our results show a high level of positivity for HBV in the children with cancer studied. In spite of being asymptomatic carriers of the HBV, it is noticeable the presence of serological markers for acute disease. We recommend testing for HBV serological markers before starting chemotherapy. Should the test results be negative, vaccination is indicated and should they be positive, specialized care is indicated.</abstract><cop>Peru</cop><pmid>17053821</pmid><tpages>6</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1022-5129 |
| ispartof | Revista de gastroenterología del Perú, 2006-07, Vol.26 (3), p.259-264 |
| issn | 1022-5129 |
| language | spa |
| recordid | cdi_proquest_miscellaneous_68984017 |
| source | MEDLINE; EZB-FREE-00999 freely available EZB journals |
| subjects | Adolescent Carrier State - epidemiology Child Child, Preschool Female Hepatitis B - blood Hepatitis B - complications Hepatitis B - epidemiology Hepatitis B Antigens - blood Hepatitis B Surface Antigens - blood Hepatitis B virus - immunology Hepatitis B virus - isolation & purification Humans Liver Function Tests Male Neoplasms - blood Neoplasms - complications Prevalence Seroepidemiologic Studies Venezuela - epidemiology |
| title | Hepatitis B in children with cancer |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-12T00%3A33%3A35IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Hepatitis%20B%20in%20children%20with%20cancer&rft.jtitle=Revista%20de%20gastroenterolog%C3%ADa%20del%20Per%C3%BA&rft.au=Espinoza%20Holguin,%20Maurin&rft.date=2006-07&rft.volume=26&rft.issue=3&rft.spage=259&rft.epage=264&rft.pages=259-264&rft.issn=1022-5129&rft_id=info:doi/&rft_dat=%3Cproquest_pubme%3E68984017%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=68984017&rft_id=info:pmid/17053821&rfr_iscdi=true |