Intranasal CpG DNA therapy during allergen exposure in allergic rhinitis

1) To estimate the effectiveness of intranasal administration of CpG DNA alone on allergic rhinitis compared with intradermal administration; and 2) to find out how CpG DNA therapy is useful in treatment of allergic rhinitis. Mice were intraperitoneally sensitized and intranasally challenged with Ja...

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Bibliographische Detailangaben
Veröffentlicht in:	Otolaryngology-head and neck surgery 2007-02, Vol.136 (2), p.246-251
Hauptverfasser:	Suzuki, Motohiko, Matsumoto, Tamami, Ohta, Nobuo, Min, Wei-Ping, Murakami, Shingo
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Cutaneous Administration, Intranasal Administration, Oral Allergens - immunology Animals CpG Islands - immunology Cryptomeria - immunology Enzyme-Linked Immunosorbent Assay Eosinophilia - prevention & control Epitopes, T-Lymphocyte Female Immunoglobulin E - immunology Interleukin-5 - immunology Lymphocytes - immunology Mice Mice, Inbred BALB C Mice, Inbred C57BL Pollen - immunology Rhinitis - drug therapy Rhinitis - immunology
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