Platelet-Rich Plasma: A Review of Biology and Applications in Plastic Surgery
Healing of hard and soft tissue is mediated by a complex array of intracellular and extracellular events that are regulated by signaling proteins, a process that is, at present, incompletely understood. What is certain, however, is that platelets play a prominent if not deciding role. Controlled ani...
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| Veröffentlicht in: | Plastic and reconstructive surgery (1963) 2006-11, Vol.118 (6), p.147e-159e |
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| container_title | Plastic and reconstructive surgery (1963) |
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| creator | Eppley, Barry L. Pietrzak, William S. Blanton, Matthew |
| description | Healing of hard and soft tissue is mediated by a complex array of intracellular and extracellular events that are regulated by signaling proteins, a process that is, at present, incompletely understood. What is certain, however, is that platelets play a prominent if not deciding role. Controlled animal studies of soft and hard tissues have suggested that the application of autogenous platelet-rich plasma can enhance wound healing. The clinical use of platelet-rich plasma for a wide variety of applications has been reported; however, many reports are anecdotal and few include controls to definitively determine the role of platelet-rich plasma. The authors describe platelet biology and its role in wound healing; the preparation, characterization, and use of platelet-rich plasma; and those applications in plastic surgery for which it may be useful. |
| doi_str_mv | 10.1097/01.prs.0000239606.92676.cf |
| format | Article |
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| identifier | ISSN: 0032-1052 |
| ispartof | Plastic and reconstructive surgery (1963), 2006-11, Vol.118 (6), p.147e-159e |
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| language | eng |
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| source | MEDLINE; Journals@Ovid Ovid Autoload |
| subjects | Animals Blood Coagulation - physiology Blood Platelets - physiology Blood Transfusion, Autologous Hemostasis - physiology Humans Plasma - physiology Platelet Activation - physiology Platelet Transfusion Platelet-Derived Growth Factor Reconstructive Surgical Procedures - methods Wound Healing - physiology |
| title | Platelet-Rich Plasma: A Review of Biology and Applications in Plastic Surgery |
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