Altered myogenic constriction and endothelium-derived hyperpolarizing factor-mediated relaxation in small mesenteric arteries of hypertensive subtotally nephrectomized rats

Chronic renal failure (CRF) is associated with altered systemic arterial tone and hypertension. Myogenic constriction and endothelium-derived hyperpolarizing factor (EDHF)-dependent relaxation represent major vasoregulatory mechanisms in small systemic arteries. Elevated myogenic response and impair...

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Veröffentlicht in:	Journal of hypertension 2006-11, Vol.24 (11), p.2215-2223
Hauptverfasser:	Vettoretti, Simone, Ochodnicky, Peter, Buikema, Hendrik, Henning, Rob H, Kluppel, C Alex, de Zeeuw, Dick, van Dokkum, Richard P E
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiography Angiotensin-Converting Enzyme Inhibitors - pharmacology Animals Biological Factors - physiology Hypertension - etiology Hypertension - physiopathology Kidney Failure, Chronic - complications Kidney Failure, Chronic - physiopathology Lisinopril - pharmacology Male Mesenteric Arteries - drug effects Mesenteric Arteries - physiopathology Models, Animal Muscle Contraction - physiology Muscle, Smooth - physiopathology Nephrectomy Rats Rats, Wistar Vasoconstriction - physiology Vasodilation - physiology
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