Prevalence of Age-related Maculopathy in the Adult Population in China: The Beijing Eye Study

To evaluate the prevalence of age-related maculopathy (ARM) in adult Chinese living in rural or urban regions of mainland China. Population-based prevalence study. The study included 4439 subjects (aged 40 or more years) out of 5324 subjects invited to participate (response rate 83.4%). It was held...

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Veröffentlicht in:American journal of ophthalmology 2006-11, Vol.142 (5), p.788-793.e1
Hauptverfasser: Li, Yibin, Xu, Liang, Jonas, Jost B., Yang, Hua, Ma, Yingnan, Li, Jianjun
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container_end_page 793.e1
container_issue 5
container_start_page 788
container_title American journal of ophthalmology
container_volume 142
creator Li, Yibin
Xu, Liang
Jonas, Jost B.
Yang, Hua
Ma, Yingnan
Li, Jianjun
description To evaluate the prevalence of age-related maculopathy (ARM) in adult Chinese living in rural or urban regions of mainland China. Population-based prevalence study. The study included 4439 subjects (aged 40 or more years) out of 5324 subjects invited to participate (response rate 83.4%). It was held in rural and urban regions of Greater Beijing. The participants underwent a detailed ophthalmic examination including fundus photography. All fundus photographs were graded by the Wisconsin Age-Related Maculopathy Grading System. Fundus photographs were available for 4376 (98.6%) subjects. Early ARM was present in 122 (1.4%) of 8655 (95% confidence interval [CI] 1.16% to 1.66%) eyes or 63 (1.4%) of 4376 (95% CI 1.09% to 1.79%) subjects, late ARM in 12 (0.14%) of 8655 (95% CI 0.06% to 0.22%) eyes or seven (0.2%) of 4376 (95% CI 0.04% to 0.28%) subjects, and exudative ARM as part of late ARM in seven (0.1%) of 8655 (95% CI 0.02% to 0.14%) eyes or six (0.1%) of 4376 (95% CI 0.03% to 0.25%) subjects. The prevalence of early ARM, late ARM, and exudative ARM, respectively, increased from 0.61%, 0.07%, and 0.07% in the 40-to-44-year age group, to 1.66%, 0.26%, and 0.26% in the 55-to-59-year group, and to 2.99%, 0.90%, and 0.60% in the group aged 75 years and older. ARM was causative for visual impairment (best-corrected visual acuity in the better eye,
doi_str_mv 10.1016/j.ajo.2006.06.001
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Population-based prevalence study. The study included 4439 subjects (aged 40 or more years) out of 5324 subjects invited to participate (response rate 83.4%). It was held in rural and urban regions of Greater Beijing. The participants underwent a detailed ophthalmic examination including fundus photography. All fundus photographs were graded by the Wisconsin Age-Related Maculopathy Grading System. Fundus photographs were available for 4376 (98.6%) subjects. Early ARM was present in 122 (1.4%) of 8655 (95% confidence interval [CI] 1.16% to 1.66%) eyes or 63 (1.4%) of 4376 (95% CI 1.09% to 1.79%) subjects, late ARM in 12 (0.14%) of 8655 (95% CI 0.06% to 0.22%) eyes or seven (0.2%) of 4376 (95% CI 0.04% to 0.28%) subjects, and exudative ARM as part of late ARM in seven (0.1%) of 8655 (95% CI 0.02% to 0.14%) eyes or six (0.1%) of 4376 (95% CI 0.03% to 0.25%) subjects. The prevalence of early ARM, late ARM, and exudative ARM, respectively, increased from 0.61%, 0.07%, and 0.07% in the 40-to-44-year age group, to 1.66%, 0.26%, and 0.26% in the 55-to-59-year group, and to 2.99%, 0.90%, and 0.60% in the group aged 75 years and older. ARM was causative for visual impairment (best-corrected visual acuity in the better eye, &lt;20/60 and ≥20/400) or blindness (visual acuity &lt;20/400) in one subject (0.023%). 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Population-based prevalence study. The study included 4439 subjects (aged 40 or more years) out of 5324 subjects invited to participate (response rate 83.4%). It was held in rural and urban regions of Greater Beijing. The participants underwent a detailed ophthalmic examination including fundus photography. All fundus photographs were graded by the Wisconsin Age-Related Maculopathy Grading System. Fundus photographs were available for 4376 (98.6%) subjects. Early ARM was present in 122 (1.4%) of 8655 (95% confidence interval [CI] 1.16% to 1.66%) eyes or 63 (1.4%) of 4376 (95% CI 1.09% to 1.79%) subjects, late ARM in 12 (0.14%) of 8655 (95% CI 0.06% to 0.22%) eyes or seven (0.2%) of 4376 (95% CI 0.04% to 0.28%) subjects, and exudative ARM as part of late ARM in seven (0.1%) of 8655 (95% CI 0.02% to 0.14%) eyes or six (0.1%) of 4376 (95% CI 0.03% to 0.25%) subjects. The prevalence of early ARM, late ARM, and exudative ARM, respectively, increased from 0.61%, 0.07%, and 0.07% in the 40-to-44-year age group, to 1.66%, 0.26%, and 0.26% in the 55-to-59-year group, and to 2.99%, 0.90%, and 0.60% in the group aged 75 years and older. ARM was causative for visual impairment (best-corrected visual acuity in the better eye, &lt;20/60 and ≥20/400) or blindness (visual acuity &lt;20/400) in one subject (0.023%). 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Xu, Liang ; Jonas, Jost B. ; Yang, Hua ; Ma, Yingnan ; Li, Jianjun</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c475t-20dd03e427b9685f28c78bbc98ff4aea6307ac25179fa8c4c43abe66ede2489e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2006</creationdate><topic>Adult</topic><topic>Age</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Asian Continental Ancestry Group - statistics &amp; numerical data</topic><topic>Biological and medical sciences</topic><topic>Blindness - epidemiology</topic><topic>Cataracts</topic><topic>China - epidemiology</topic><topic>Female</topic><topic>Humans</topic><topic>Macular degeneration</topic><topic>Macular Degeneration - epidemiology</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Miscellaneous</topic><topic>Older people</topic><topic>Ophthalmology</topic><topic>Photography</topic><topic>Population</topic><topic>Prevalence</topic><topic>Rural Population - statistics &amp; numerical data</topic><topic>Studies</topic><topic>Urban Population - statistics &amp; numerical data</topic><topic>Vision, Low - epidemiology</topic><topic>Visual impairment</topic><topic>Visually Impaired Persons - statistics &amp; numerical data</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Li, Yibin</creatorcontrib><creatorcontrib>Xu, Liang</creatorcontrib><creatorcontrib>Jonas, Jost B.</creatorcontrib><creatorcontrib>Yang, Hua</creatorcontrib><creatorcontrib>Ma, Yingnan</creatorcontrib><creatorcontrib>Li, Jianjun</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>Nursing &amp; Allied Health Premium</collection><collection>MEDLINE - Academic</collection><jtitle>American journal of ophthalmology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Li, Yibin</au><au>Xu, Liang</au><au>Jonas, Jost B.</au><au>Yang, Hua</au><au>Ma, Yingnan</au><au>Li, Jianjun</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Prevalence of Age-related Maculopathy in the Adult Population in China: The Beijing Eye Study</atitle><jtitle>American journal of ophthalmology</jtitle><addtitle>Am J Ophthalmol</addtitle><date>2006-11-01</date><risdate>2006</risdate><volume>142</volume><issue>5</issue><spage>788</spage><epage>793.e1</epage><pages>788-793.e1</pages><issn>0002-9394</issn><eissn>1879-1891</eissn><coden>AJOPAA</coden><abstract>To evaluate the prevalence of age-related maculopathy (ARM) in adult Chinese living in rural or urban regions of mainland China. Population-based prevalence study. The study included 4439 subjects (aged 40 or more years) out of 5324 subjects invited to participate (response rate 83.4%). It was held in rural and urban regions of Greater Beijing. The participants underwent a detailed ophthalmic examination including fundus photography. All fundus photographs were graded by the Wisconsin Age-Related Maculopathy Grading System. Fundus photographs were available for 4376 (98.6%) subjects. Early ARM was present in 122 (1.4%) of 8655 (95% confidence interval [CI] 1.16% to 1.66%) eyes or 63 (1.4%) of 4376 (95% CI 1.09% to 1.79%) subjects, late ARM in 12 (0.14%) of 8655 (95% CI 0.06% to 0.22%) eyes or seven (0.2%) of 4376 (95% CI 0.04% to 0.28%) subjects, and exudative ARM as part of late ARM in seven (0.1%) of 8655 (95% CI 0.02% to 0.14%) eyes or six (0.1%) of 4376 (95% CI 0.03% to 0.25%) subjects. The prevalence of early ARM, late ARM, and exudative ARM, respectively, increased from 0.61%, 0.07%, and 0.07% in the 40-to-44-year age group, to 1.66%, 0.26%, and 0.26% in the 55-to-59-year group, and to 2.99%, 0.90%, and 0.60% in the group aged 75 years and older. ARM was causative for visual impairment (best-corrected visual acuity in the better eye, &lt;20/60 and ≥20/400) or blindness (visual acuity &lt;20/400) in one subject (0.023%). Visual impairment due to ARM was relatively uncommon in the adult Chinese population in rural and urban regions.</abstract><cop>New York, NY</cop><pub>Elsevier Inc</pub><pmid>16989759</pmid><doi>10.1016/j.ajo.2006.06.001</doi><tpages>6</tpages></addata></record>
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subjects Adult
Age
Aged
Aged, 80 and over
Asian Continental Ancestry Group - statistics & numerical data
Biological and medical sciences
Blindness - epidemiology
Cataracts
China - epidemiology
Female
Humans
Macular degeneration
Macular Degeneration - epidemiology
Male
Medical sciences
Middle Aged
Miscellaneous
Older people
Ophthalmology
Photography
Population
Prevalence
Rural Population - statistics & numerical data
Studies
Urban Population - statistics & numerical data
Vision, Low - epidemiology
Visual impairment
Visually Impaired Persons - statistics & numerical data
title Prevalence of Age-related Maculopathy in the Adult Population in China: The Beijing Eye Study
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