99mTc(CO) 3-VIP analogues: Preparation and evaluation as tumor imaging agent

Vasoactive intestinal peptide (VIP) receptors are expressed abundantly on many types of tumors and, hence, radiolabeled VIP analogues are being explored for tumor imaging and therapy. Here, we report synthesis of three VIP analogues and their radiolabeling with 99mTc via a novel tricarbonyl synthon....

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Veröffentlicht in:	Applied radiation and isotopes 2007-04, Vol.65 (4), p.382-386
Hauptverfasser:	Kothari, Kanchan, Prasad, Sudhanand, Korde, Aruna, Mukherjee, Archana, Mathur, Archana, Jaggi, Manu, Venkatesh, Meera, Pillai, Ambikalmajan M.R., Mukherjee, Rama, Ramamoorthy, Natesan
Format:	Artikel
Sprache:	eng
Schlagworte:	99mTc(I) tricarbonyl complexes Amino Acid Sequence Animals Colonic Neoplasms - diagnostic imaging Humans Isotope Labeling Mice Organotechnetium Compounds - chemical synthesis Organotechnetium Compounds - pharmacokinetics Radionuclide Imaging Tumor imaging Vasoactive Intestinal Peptide - analogs & derivatives Vasoactive Intestinal Peptide - chemical synthesis Vasoactive Intestinal Peptide - pharmacokinetics VIP
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