Medicinal flowers. XII.(1)) New spirostane-type steroid saponins with antidiabetogenic activity from Borassus flabellifer

The methanolic extract from the male flowers of Borassus flabellifer was found to inhibit the increase of serum glucose levels in sucrose-loaded rats at a dose of 250 mg/kg, p.o. From the methanolic extract, six new spirostane-type steroid saponins, borassosides A-F (1-6), were isolated together wit...

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Veröffentlicht in:	Chemical & pharmaceutical bulletin 2007-02, Vol.55 (2), p.308-316
Hauptverfasser:	Yoshikawa, Masayuki, Xu, Fengming, Morikawa, Toshio, Pongpiriyadacha, Yutana, Nakamura, Seikou, Asao, Yasunobu, Kumahara, Akira, Matsuda, Hisashi
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Arecaceae - chemistry Blood Glucose - metabolism Diosgenin - analogs & derivatives Diosgenin - chemistry Diosgenin - isolation & purification Diosgenin - pharmacology Dose-Response Relationship, Drug Hypoglycemic Agents - pharmacology Male Methanol - chemistry Molecular Structure Plant Extracts - chemistry Plants, Medicinal - chemistry Rats Rats, Wistar Saponins - chemistry Saponins - isolation & purification Saponins - pharmacology Time Factors
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