Intracellular drug delivery by sulfatide-mediated liposomes to gliomas

We described here a liposomal carrier system in which the targeting ligand was sulfatide, a glycosphingolipid known to bind several extracellular matrix (ECM) glycoproteins whose expression was highly up-regulated in many tumors. In vitro experiments with human glioma cell lines demonstrated that ro...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of controlled release 2006-10, Vol.115 (2), p.150-157
Hauptverfasser:	Shao, Ke, Hou, Qingsong, Duan, Wei, Go, Mei Lin, Wong, Kim Ping, Li, Qiu-Tian
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibiotics, Antineoplastic - administration & dosage Antibiotics, Antineoplastic - pharmacokinetics Biological and medical sciences Brain Neoplasms - drug therapy Cell Line, Tumor Cell Nucleus - metabolism Cell Survival - drug effects Cytosol - metabolism Doxorubicin Doxorubicin - administration & dosage Doxorubicin - pharmacokinetics Drug Carriers Drug Delivery Systems General pharmacology Glioma - drug therapy Gliomas Humans Intracellular drug delivery Liposomes Medical sciences Mice Mice, Nude Microscopy, Fluorescence Neoplasm Transplantation Pharmaceutical technology. Pharmaceutical industry Pharmacology. Drug treatments Sulfatide Sulfoglycosphingolipids - pharmacology Survival Transplantation, Heterologous
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!