Peroxynitrite and myocardial contractility: In vivo versus in vitro effects

Generation of peroxynitrite (ONOO −) as a result of altered redox balance has been shown to affect cardiac function; however, inconsistencies in the data exist, particularly for myocardial contractility. The hypothesis that the cardiac impact of ONOO − formation depends on its site of generation, in...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Free radical biology & medicine 2006-11, Vol.41 (10), p.1606-1618
Hauptverfasser:	Katori, Tatsuo, Donzelli, Sonia, Tocchetti, Carlo G., Miranda, Katrina M., Cormaci, Gianfrancesco, Thomas, Douglas D., Ketner, Elizabeth A., Lee, Myung Jae, Mancardi, Daniele, Wink, David A., Kass, David A., Paolocci, Nazareno
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenergic (ant)agonists Adrenergic beta-Agonists - pharmacology Angeli's salt Animals Blood Pressure - drug effects Calcium - metabolism Contractile function Diastole - drug effects Dobutamine - antagonists & inhibitors Dobutamine - pharmacology Dogs Heart - drug effects Heart failure In Vitro Techniques Isolated myocytes Mice Mice, Inbred C57BL Myocardial Contraction - drug effects Myocytes, Cardiac - drug effects Myocytes, Cardiac - metabolism Nitric oxide Nitroxyl (HNO) Peroxynitrite Peroxynitrous Acid - metabolism Peroxynitrous Acid - pharmacology Stroke Volume - drug effects
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!