A proteomic analysis during serial subculture and osteogenic differentiation of human mesenchymal stem cell

Although previous studies have reported the effects of extensive subculturing on proliferation rates and osteogenic potential of human mesenchymal stem cells (hMSCs), the results remain controversial. The aim of our study was to characterize the proliferation and osteogenic potential of hMSCs during...

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Veröffentlicht in:	Journal of orthopaedic research 2006-11, Vol.24 (11), p.2059-2071
Hauptverfasser:	Sun, Hyun Jin, Bahk, Young Yil, Choi, Yon Rak, Shim, Jung Hye, Han, Seung Hwan, Lee, Jin Woo
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Biomarkers - metabolism Bone Marrow Cells - cytology Bone Marrow Cells - metabolism Cell Culture Techniques Cell Differentiation Cell Proliferation Cells, Cultured Chaperonin Containing TCP-1 Chaperonins Chloride Channels - genetics Chloride Channels - metabolism Down-Regulation Female Heat-Shock Proteins - genetics Heat-Shock Proteins - metabolism Histocytochemistry human mesenchymal stem cells Humans Male Mesenchymal Stromal Cells - cytology Mesenchymal Stromal Cells - metabolism Middle Aged Molecular Chaperones - genetics Molecular Chaperones - metabolism Osteogenesis - physiology osteogenic differentiation Proteome proteome analysis Proteomics regulatory factors RNA, Messenger - metabolism subculture
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