Incidence of schizophrenia and other psychoses in ethnic minority groups: results from the MRC AESOP Study

Background. The incidence of schizophrenia in the African-Caribbean population in England is reported to be raised. We sought to clarify whether (a) the rates of other psychotic disorders are increased, (b) whether psychosis is increased in other ethnic minority groups, and (c) whether particular ag...

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Veröffentlicht in:Psychological medicine 2006-11, Vol.36 (11), p.1541-1550
Hauptverfasser: FEARON, PAUL, KIRKBRIDE, JAMES B., MORGAN, CRAIG, DAZZAN, PAOLA, MORGAN, KEVIN, LLOYD, TUHINA, HUTCHINSON, GERARD, TARRANT, JANE, LUN ALAN FUNG, WAI, HOLLOWAY, JOHN, MALLETT, ROSEMARIE, HARRISON, GLYNN, LEFF, JULIAN, JONES, PETER B., MURRAY, ROBIN M.
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container_end_page 1550
container_issue 11
container_start_page 1541
container_title Psychological medicine
container_volume 36
creator FEARON, PAUL
KIRKBRIDE, JAMES B.
MORGAN, CRAIG
DAZZAN, PAOLA
MORGAN, KEVIN
LLOYD, TUHINA
HUTCHINSON, GERARD
TARRANT, JANE
LUN ALAN FUNG, WAI
HOLLOWAY, JOHN
MALLETT, ROSEMARIE
HARRISON, GLYNN
LEFF, JULIAN
JONES, PETER B.
MURRAY, ROBIN M.
description Background. The incidence of schizophrenia in the African-Caribbean population in England is reported to be raised. We sought to clarify whether (a) the rates of other psychotic disorders are increased, (b) whether psychosis is increased in other ethnic minority groups, and (c) whether particular age or gender groups are especially at risk. Method. We identified all people (n=568) aged 16–64 years presenting to secondary services with their first psychotic symptoms in three well-defined English areas (over a 2-year period in Southeast London and Nottingham and a 9-month period in Bristol). Standardized incidence rates and incidence rate ratios (IRR) for all major psychosis syndromes for all main ethnic groups were calculated. Results. We found remarkably high IRRs for both schizophrenia and manic psychosis in both African-Caribbeans (schizophrenia 9·1, manic psychosis 8·0) and Black Africans (schizophrenia 5·8, manic psychosis 6·2) in men and women. IRRs in other ethnic minority groups were modestly increased as were rates for depressive psychosis and other psychoses in all minority groups. These raised rates were evident in all age groups in our study. Conclusions. Ethnic minority groups are at increased risk for all psychotic illnesses but African-Caribbeans and Black Africans appear to be at especially high risk for both schizophrenia and mania. These findings suggest that (a) either additional risk factors are operating in African-Caribbeans and Black Africans or that these factors are particularly prevalent in these groups, and that (b) such factors increase risk for schizophrenia and mania in these groups.
doi_str_mv 10.1017/S0033291706008774
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The incidence of schizophrenia in the African-Caribbean population in England is reported to be raised. We sought to clarify whether (a) the rates of other psychotic disorders are increased, (b) whether psychosis is increased in other ethnic minority groups, and (c) whether particular age or gender groups are especially at risk. Method. We identified all people (n=568) aged 16–64 years presenting to secondary services with their first psychotic symptoms in three well-defined English areas (over a 2-year period in Southeast London and Nottingham and a 9-month period in Bristol). Standardized incidence rates and incidence rate ratios (IRR) for all major psychosis syndromes for all main ethnic groups were calculated. Results. We found remarkably high IRRs for both schizophrenia and manic psychosis in both African-Caribbeans (schizophrenia 9·1, manic psychosis 8·0) and Black Africans (schizophrenia 5·8, manic psychosis 6·2) in men and women. IRRs in other ethnic minority groups were modestly increased as were rates for depressive psychosis and other psychoses in all minority groups. These raised rates were evident in all age groups in our study. Conclusions. Ethnic minority groups are at increased risk for all psychotic illnesses but African-Caribbeans and Black Africans appear to be at especially high risk for both schizophrenia and mania. These findings suggest that (a) either additional risk factors are operating in African-Caribbeans and Black Africans or that these factors are particularly prevalent in these groups, and that (b) such factors increase risk for schizophrenia and mania in these groups.</description><identifier>ISSN: 0033-2917</identifier><identifier>EISSN: 1469-8978</identifier><identifier>DOI: 10.1017/S0033291706008774</identifier><identifier>PMID: 16938150</identifier><identifier>CODEN: PSMDCO</identifier><language>eng</language><publisher>Cambridge, UK: Cambridge University Press</publisher><subject>Adolescent ; Adult ; Adult and adolescent clinical studies ; Age differences ; Age Factors ; Biological and medical sciences ; Black people ; Blacks - ethnology ; Blacks - psychology ; Blacks - statistics &amp; numerical data ; Cross-Sectional Studies ; England ; Epidemiology ; Ethnic minorities ; Female ; Gender differences ; General aspects ; Humans ; Incidence ; Male ; Medical sciences ; Middle Aged ; Minority &amp; ethnic groups ; Minority Groups - psychology ; Minority Groups - statistics &amp; numerical data ; Original Article ; Psychology ; Psychology. Psychoanalysis. Psychiatry ; Psychopathology. Psychiatry ; Psychoses ; Psychotic Disorders - epidemiology ; Psychotic Disorders - ethnology ; Public health. Hygiene ; Public health. Hygiene-occupational medicine ; Risk ; Risk factors ; Schizophrenia ; Schizophrenia - epidemiology ; Schizophrenia - ethnology</subject><ispartof>Psychological medicine, 2006-11, Vol.36 (11), p.1541-1550</ispartof><rights>2006 Cambridge University Press</rights><rights>2007 INIST-CNRS</rights><rights>Copyright Cambridge University Press, Publishing Division Nov 2006</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c609t-d858838694be1e8bf8522c88c55b6c601dcb624d9ab5958ac66c1859525df1713</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.cambridge.org/core/product/identifier/S0033291706008774/type/journal_article$$EHTML$$P50$$Gcambridge$$H</linktohtml><link.rule.ids>164,314,776,780,12825,27901,27902,30976,30977,55603</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&amp;idt=18248142$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/16938150$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>FEARON, PAUL</creatorcontrib><creatorcontrib>KIRKBRIDE, JAMES B.</creatorcontrib><creatorcontrib>MORGAN, CRAIG</creatorcontrib><creatorcontrib>DAZZAN, PAOLA</creatorcontrib><creatorcontrib>MORGAN, KEVIN</creatorcontrib><creatorcontrib>LLOYD, TUHINA</creatorcontrib><creatorcontrib>HUTCHINSON, GERARD</creatorcontrib><creatorcontrib>TARRANT, JANE</creatorcontrib><creatorcontrib>LUN ALAN FUNG, WAI</creatorcontrib><creatorcontrib>HOLLOWAY, JOHN</creatorcontrib><creatorcontrib>MALLETT, ROSEMARIE</creatorcontrib><creatorcontrib>HARRISON, GLYNN</creatorcontrib><creatorcontrib>LEFF, JULIAN</creatorcontrib><creatorcontrib>JONES, PETER B.</creatorcontrib><creatorcontrib>MURRAY, ROBIN M.</creatorcontrib><creatorcontrib>AESOP Study Group</creatorcontrib><title>Incidence of schizophrenia and other psychoses in ethnic minority groups: results from the MRC AESOP Study</title><title>Psychological medicine</title><addtitle>Psychol. Med</addtitle><description>Background. The incidence of schizophrenia in the African-Caribbean population in England is reported to be raised. We sought to clarify whether (a) the rates of other psychotic disorders are increased, (b) whether psychosis is increased in other ethnic minority groups, and (c) whether particular age or gender groups are especially at risk. Method. We identified all people (n=568) aged 16–64 years presenting to secondary services with their first psychotic symptoms in three well-defined English areas (over a 2-year period in Southeast London and Nottingham and a 9-month period in Bristol). Standardized incidence rates and incidence rate ratios (IRR) for all major psychosis syndromes for all main ethnic groups were calculated. Results. We found remarkably high IRRs for both schizophrenia and manic psychosis in both African-Caribbeans (schizophrenia 9·1, manic psychosis 8·0) and Black Africans (schizophrenia 5·8, manic psychosis 6·2) in men and women. IRRs in other ethnic minority groups were modestly increased as were rates for depressive psychosis and other psychoses in all minority groups. These raised rates were evident in all age groups in our study. Conclusions. Ethnic minority groups are at increased risk for all psychotic illnesses but African-Caribbeans and Black Africans appear to be at especially high risk for both schizophrenia and mania. These findings suggest that (a) either additional risk factors are operating in African-Caribbeans and Black Africans or that these factors are particularly prevalent in these groups, and that (b) such factors increase risk for schizophrenia and mania in these groups.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Adult and adolescent clinical studies</subject><subject>Age differences</subject><subject>Age Factors</subject><subject>Biological and medical sciences</subject><subject>Black people</subject><subject>Blacks - ethnology</subject><subject>Blacks - psychology</subject><subject>Blacks - statistics &amp; numerical data</subject><subject>Cross-Sectional Studies</subject><subject>England</subject><subject>Epidemiology</subject><subject>Ethnic minorities</subject><subject>Female</subject><subject>Gender differences</subject><subject>General aspects</subject><subject>Humans</subject><subject>Incidence</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Minority &amp; ethnic groups</subject><subject>Minority Groups - psychology</subject><subject>Minority Groups - statistics &amp; numerical data</subject><subject>Original Article</subject><subject>Psychology</subject><subject>Psychology. 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Hygiene-occupational medicine</subject><subject>Risk</subject><subject>Risk factors</subject><subject>Schizophrenia</subject><subject>Schizophrenia - epidemiology</subject><subject>Schizophrenia - ethnology</subject><issn>0033-2917</issn><issn>1469-8978</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2006</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>7QJ</sourceid><sourceid>8G5</sourceid><sourceid>BENPR</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNqF0V1rFDEUBuAgil2rP8AbCYLejeZ7Eu_KUruFStX14zJkMplO1p3JNJmBbn-9WXZwQZFeJXCeczjJC8BLjN5hhMv3a4QoJQqXSCAky5I9AgvMhCqkKuVjsNiXi339BDxLaYMQppiRp-AEC0Ul5mgBNpe99bXrrYOhgcm2_j4MbXS9N9D0NQxj6yIc0s62IbkEfQ_d2Pbews73IfpxB29imIb0AUaXpu2YYBNDB3Mb_PR1Cc_O19ef4Xqc6t1z8KQx2-RezOcp-P7x_NtyVVxdX1wuz64KK5Aai1pyKakUilUOO1k1khNipbScVyITXNtKEFYrU3HFpbFCWCzzlfC6wSWmp-DtYe4Qw-3k0qg7n6zbbk3vwpS0kEownL_mIchLpARR6kGIFVX7b87w9V9wE6bY59dqghhTlHCeET4gG0NK0TV6iL4zcacx0vtc9T-55p5X8-Cp6lx97JiDzODNDEyyZttEk3NNRycJkzn77IqD82l0d3_qJv7SoqQl1-Lii2bi52q1Ziv9I3s6L2u6Kvr6xh2f9P91fwNwrMcH</recordid><startdate>20061101</startdate><enddate>20061101</enddate><creator>FEARON, PAUL</creator><creator>KIRKBRIDE, JAMES B.</creator><creator>MORGAN, CRAIG</creator><creator>DAZZAN, PAOLA</creator><creator>MORGAN, KEVIN</creator><creator>LLOYD, TUHINA</creator><creator>HUTCHINSON, GERARD</creator><creator>TARRANT, JANE</creator><creator>LUN ALAN FUNG, WAI</creator><creator>HOLLOWAY, JOHN</creator><creator>MALLETT, ROSEMARIE</creator><creator>HARRISON, GLYNN</creator><creator>LEFF, JULIAN</creator><creator>JONES, PETER B.</creator><creator>MURRAY, ROBIN M.</creator><general>Cambridge University Press</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>0-V</scope><scope>3V.</scope><scope>7QJ</scope><scope>7QP</scope><scope>7QR</scope><scope>7RV</scope><scope>7TK</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>88G</scope><scope>8FD</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>ALSLI</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>HEHIP</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M1P</scope><scope>M2M</scope><scope>M2O</scope><scope>M2S</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>P64</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PSYQQ</scope><scope>Q9U</scope><scope>7X8</scope></search><sort><creationdate>20061101</creationdate><title>Incidence of schizophrenia and other psychoses in ethnic minority groups: results from the MRC AESOP Study</title><author>FEARON, PAUL ; KIRKBRIDE, JAMES B. ; MORGAN, CRAIG ; DAZZAN, PAOLA ; MORGAN, KEVIN ; LLOYD, TUHINA ; HUTCHINSON, GERARD ; TARRANT, JANE ; LUN ALAN FUNG, WAI ; HOLLOWAY, JOHN ; MALLETT, ROSEMARIE ; HARRISON, GLYNN ; LEFF, JULIAN ; JONES, PETER B. ; MURRAY, ROBIN M.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c609t-d858838694be1e8bf8522c88c55b6c601dcb624d9ab5958ac66c1859525df1713</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2006</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Adult and adolescent clinical studies</topic><topic>Age differences</topic><topic>Age Factors</topic><topic>Biological and medical sciences</topic><topic>Black people</topic><topic>Blacks - ethnology</topic><topic>Blacks - psychology</topic><topic>Blacks - statistics &amp; numerical data</topic><topic>Cross-Sectional Studies</topic><topic>England</topic><topic>Epidemiology</topic><topic>Ethnic minorities</topic><topic>Female</topic><topic>Gender differences</topic><topic>General aspects</topic><topic>Humans</topic><topic>Incidence</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Minority &amp; ethnic groups</topic><topic>Minority Groups - psychology</topic><topic>Minority Groups - statistics &amp; numerical data</topic><topic>Original Article</topic><topic>Psychology</topic><topic>Psychology. 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Med</addtitle><date>2006-11-01</date><risdate>2006</risdate><volume>36</volume><issue>11</issue><spage>1541</spage><epage>1550</epage><pages>1541-1550</pages><issn>0033-2917</issn><eissn>1469-8978</eissn><coden>PSMDCO</coden><abstract>Background. The incidence of schizophrenia in the African-Caribbean population in England is reported to be raised. We sought to clarify whether (a) the rates of other psychotic disorders are increased, (b) whether psychosis is increased in other ethnic minority groups, and (c) whether particular age or gender groups are especially at risk. Method. We identified all people (n=568) aged 16–64 years presenting to secondary services with their first psychotic symptoms in three well-defined English areas (over a 2-year period in Southeast London and Nottingham and a 9-month period in Bristol). Standardized incidence rates and incidence rate ratios (IRR) for all major psychosis syndromes for all main ethnic groups were calculated. Results. We found remarkably high IRRs for both schizophrenia and manic psychosis in both African-Caribbeans (schizophrenia 9·1, manic psychosis 8·0) and Black Africans (schizophrenia 5·8, manic psychosis 6·2) in men and women. IRRs in other ethnic minority groups were modestly increased as were rates for depressive psychosis and other psychoses in all minority groups. These raised rates were evident in all age groups in our study. Conclusions. Ethnic minority groups are at increased risk for all psychotic illnesses but African-Caribbeans and Black Africans appear to be at especially high risk for both schizophrenia and mania. These findings suggest that (a) either additional risk factors are operating in African-Caribbeans and Black Africans or that these factors are particularly prevalent in these groups, and that (b) such factors increase risk for schizophrenia and mania in these groups.</abstract><cop>Cambridge, UK</cop><pub>Cambridge University Press</pub><pmid>16938150</pmid><doi>10.1017/S0033291706008774</doi><tpages>10</tpages><oa>free_for_read</oa></addata></record>
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source Applied Social Sciences Index & Abstracts (ASSIA); MEDLINE; Cambridge Journals
subjects Adolescent
Adult
Adult and adolescent clinical studies
Age differences
Age Factors
Biological and medical sciences
Black people
Blacks - ethnology
Blacks - psychology
Blacks - statistics & numerical data
Cross-Sectional Studies
England
Epidemiology
Ethnic minorities
Female
Gender differences
General aspects
Humans
Incidence
Male
Medical sciences
Middle Aged
Minority & ethnic groups
Minority Groups - psychology
Minority Groups - statistics & numerical data
Original Article
Psychology
Psychology. Psychoanalysis. Psychiatry
Psychopathology. Psychiatry
Psychoses
Psychotic Disorders - epidemiology
Psychotic Disorders - ethnology
Public health. Hygiene
Public health. Hygiene-occupational medicine
Risk
Risk factors
Schizophrenia
Schizophrenia - epidemiology
Schizophrenia - ethnology
title Incidence of schizophrenia and other psychoses in ethnic minority groups: results from the MRC AESOP Study
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