Sarcoidosis and MIF gene polymorphism: a case-control study in an Irish population

Macrophage migration inhibitory factor is a key pro-inflammatory mediator. A 5-CATT repeat functional polymorphism within the promoter of the gene was previously associated with the lowest promoter activity. It was hypothesised that patients exhibiting a 5-CATT allele would have a less aggressive in...

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Veröffentlicht in:	The European respiratory journal 2007-02, Vol.29 (2), p.325-329
Hauptverfasser:	Plant, B. J, Ghani, S, O'Mahony, M. J, Morgan, L, O'Connor, C. M, Morgan, K, Baugh, J. A, Donnelly, S. C
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Biological and medical sciences Case-Control Studies European Continental Ancestry Group - genetics Female Gene Frequency Humans Ireland Macrophage Migration-Inhibitory Factors - genetics Male Medical sciences Microsatellite Repeats - genetics Pneumology Polymorphism, Genetic Sarcoidosis - genetics Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis Sequence Analysis, DNA
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