Direct addition of alkynes to imines and related C=N electrophiles: A convenient access to propargylamines
Propargylic amines are highly useful building blocks in organic synthesis, and the corresponding structural motif has been found in various natural products and compounds of pharmaceutical relevance. This article provides an overview of the most significant advances in the preparation of propargylic...
Gespeichert in:
| Veröffentlicht in: | Chemical communications (Cambridge, England) England), 2006-01 (41), p.4263-4275 |
|---|---|
| Hauptverfasser: | , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 4275 |
|---|---|
| container_issue | 41 |
| container_start_page | 4263 |
| container_title | Chemical communications (Cambridge, England) |
| container_volume | |
| creator | Zani, Lorenzo Bolm, Carsten |
| description | Propargylic amines are highly useful building blocks in organic synthesis, and the corresponding structural motif has been found in various natural products and compounds of pharmaceutical relevance. This article provides an overview of the most significant advances in the preparation of propargylic amines via the direct addition of alkynes to imines and related carbon-nitrogen electrophiles in the presence of metal catalysts or promoters. |
| doi_str_mv | 10.1039/b607986p |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_68963553</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>68963553</sourcerecordid><originalsourceid>FETCH-LOGICAL-c347t-3ad3df2c7a056e457c839b42b4b158340546360a01aa78db32e135ab7b92840a3</originalsourceid><addsrcrecordid>eNpFkElLBDEQhYMozriAv0ByEi-t6U7SSQsexnGFQT0oeGuyVGvG3kx6hPn3ZhawLlWH772qegidpOQiJbS41DkRhcz7HTROac4SzuTH7mrmRSIo4yN0EMKcxEq53EejVBAmJJVjNL91HsyAlbVucF2Luwqr-nvZQsBDh13jVpNqLfZQqwEsnl4_Y6ijxnf9l6shXOEJNl37C62DNjoZA2Et7iOh_OeyVmuXI7RXqTrA8bYfovf7u7fpYzJ7eXiaTmaJoUwMCVWW2iozQhGeA-PCSFpolmmm4_GUEc5ymhNFUqWEtJpmEP9UWugik4woeojONr5x_88CwlA2Lhioa9VCtwhlLoucck4jeL4Bje9C8FCVvXeN8ssyJeUq1_Jmk-trRE-3ngvdgP0Ht0HSPw-Ncu4</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>68963553</pqid></control><display><type>article</type><title>Direct addition of alkynes to imines and related C=N electrophiles: A convenient access to propargylamines</title><source>Royal Society of Chemistry Journals Archive (1841-2007)</source><source>MEDLINE</source><source>Royal Society Of Chemistry Journals 2008-</source><source>Alma/SFX Local Collection</source><creator>Zani, Lorenzo ; Bolm, Carsten</creator><creatorcontrib>Zani, Lorenzo ; Bolm, Carsten</creatorcontrib><description>Propargylic amines are highly useful building blocks in organic synthesis, and the corresponding structural motif has been found in various natural products and compounds of pharmaceutical relevance. This article provides an overview of the most significant advances in the preparation of propargylic amines via the direct addition of alkynes to imines and related carbon-nitrogen electrophiles in the presence of metal catalysts or promoters.</description><identifier>ISSN: 1359-7345</identifier><identifier>EISSN: 1364-548X</identifier><identifier>DOI: 10.1039/b607986p</identifier><identifier>PMID: 17047838</identifier><language>eng</language><publisher>England</publisher><subject>Alkynes - chemistry ; Electrons ; Imines - chemistry ; Oxidation-Reduction ; Pargyline - analogs & derivatives ; Pargyline - chemistry ; Propylamines - chemistry</subject><ispartof>Chemical communications (Cambridge, England), 2006-01 (41), p.4263-4275</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c347t-3ad3df2c7a056e457c839b42b4b158340546360a01aa78db32e135ab7b92840a3</citedby><cites>FETCH-LOGICAL-c347t-3ad3df2c7a056e457c839b42b4b158340546360a01aa78db32e135ab7b92840a3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,2818,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/17047838$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Zani, Lorenzo</creatorcontrib><creatorcontrib>Bolm, Carsten</creatorcontrib><title>Direct addition of alkynes to imines and related C=N electrophiles: A convenient access to propargylamines</title><title>Chemical communications (Cambridge, England)</title><addtitle>Chem Commun (Camb)</addtitle><description>Propargylic amines are highly useful building blocks in organic synthesis, and the corresponding structural motif has been found in various natural products and compounds of pharmaceutical relevance. This article provides an overview of the most significant advances in the preparation of propargylic amines via the direct addition of alkynes to imines and related carbon-nitrogen electrophiles in the presence of metal catalysts or promoters.</description><subject>Alkynes - chemistry</subject><subject>Electrons</subject><subject>Imines - chemistry</subject><subject>Oxidation-Reduction</subject><subject>Pargyline - analogs & derivatives</subject><subject>Pargyline - chemistry</subject><subject>Propylamines - chemistry</subject><issn>1359-7345</issn><issn>1364-548X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2006</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFkElLBDEQhYMozriAv0ByEi-t6U7SSQsexnGFQT0oeGuyVGvG3kx6hPn3ZhawLlWH772qegidpOQiJbS41DkRhcz7HTROac4SzuTH7mrmRSIo4yN0EMKcxEq53EejVBAmJJVjNL91HsyAlbVucF2Luwqr-nvZQsBDh13jVpNqLfZQqwEsnl4_Y6ijxnf9l6shXOEJNl37C62DNjoZA2Et7iOh_OeyVmuXI7RXqTrA8bYfovf7u7fpYzJ7eXiaTmaJoUwMCVWW2iozQhGeA-PCSFpolmmm4_GUEc5ymhNFUqWEtJpmEP9UWugik4woeojONr5x_88CwlA2Lhioa9VCtwhlLoucck4jeL4Bje9C8FCVvXeN8ssyJeUq1_Jmk-trRE-3ngvdgP0Ht0HSPw-Ncu4</recordid><startdate>20060101</startdate><enddate>20060101</enddate><creator>Zani, Lorenzo</creator><creator>Bolm, Carsten</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20060101</creationdate><title>Direct addition of alkynes to imines and related C=N electrophiles: A convenient access to propargylamines</title><author>Zani, Lorenzo ; Bolm, Carsten</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c347t-3ad3df2c7a056e457c839b42b4b158340546360a01aa78db32e135ab7b92840a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2006</creationdate><topic>Alkynes - chemistry</topic><topic>Electrons</topic><topic>Imines - chemistry</topic><topic>Oxidation-Reduction</topic><topic>Pargyline - analogs & derivatives</topic><topic>Pargyline - chemistry</topic><topic>Propylamines - chemistry</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Zani, Lorenzo</creatorcontrib><creatorcontrib>Bolm, Carsten</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Chemical communications (Cambridge, England)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Zani, Lorenzo</au><au>Bolm, Carsten</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Direct addition of alkynes to imines and related C=N electrophiles: A convenient access to propargylamines</atitle><jtitle>Chemical communications (Cambridge, England)</jtitle><addtitle>Chem Commun (Camb)</addtitle><date>2006-01-01</date><risdate>2006</risdate><issue>41</issue><spage>4263</spage><epage>4275</epage><pages>4263-4275</pages><issn>1359-7345</issn><eissn>1364-548X</eissn><abstract>Propargylic amines are highly useful building blocks in organic synthesis, and the corresponding structural motif has been found in various natural products and compounds of pharmaceutical relevance. This article provides an overview of the most significant advances in the preparation of propargylic amines via the direct addition of alkynes to imines and related carbon-nitrogen electrophiles in the presence of metal catalysts or promoters.</abstract><cop>England</cop><pmid>17047838</pmid><doi>10.1039/b607986p</doi><tpages>13</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1359-7345 |
| ispartof | Chemical communications (Cambridge, England), 2006-01 (41), p.4263-4275 |
| issn | 1359-7345 1364-548X |
| language | eng |
| recordid | cdi_proquest_miscellaneous_68963553 |
| source | Royal Society of Chemistry Journals Archive (1841-2007); MEDLINE; Royal Society Of Chemistry Journals 2008-; Alma/SFX Local Collection |
| subjects | Alkynes - chemistry Electrons Imines - chemistry Oxidation-Reduction Pargyline - analogs & derivatives Pargyline - chemistry Propylamines - chemistry |
| title | Direct addition of alkynes to imines and related C=N electrophiles: A convenient access to propargylamines |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-15T09%3A41%3A08IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Direct%20addition%20of%20alkynes%20to%20imines%20and%20related%20C=N%20electrophiles:%20A%20convenient%20access%20to%20propargylamines&rft.jtitle=Chemical%20communications%20(Cambridge,%20England)&rft.au=Zani,%20Lorenzo&rft.date=2006-01-01&rft.issue=41&rft.spage=4263&rft.epage=4275&rft.pages=4263-4275&rft.issn=1359-7345&rft.eissn=1364-548X&rft_id=info:doi/10.1039/b607986p&rft_dat=%3Cproquest_cross%3E68963553%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=68963553&rft_id=info:pmid/17047838&rfr_iscdi=true |