Confronting Complexity: Real-World Immunodominance in Antiviral CD8 + T Cell Responses

Antiviral CD8 + T cells respond to only a minute fraction of the potential peptide determinants encoded by viral genomes. Immunogenic determinants can be ordered into highly reproducible hierarchies based on the magnitude of cognate CD8 + T cell responses. Until recently, this phenomenon, termed imm...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Immunity (Cambridge, Mass.) Mass.), 2006-10, Vol.25 (4), p.533-543
1. Verfasser:	Yewdell, Jonathan W.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino acids Animals Antigens, Viral - genetics Antigens, Viral - immunology CD8-Positive T-Lymphocytes - immunology Evolution Genes Genomes Humans Immune system Immunodominant Epitopes - genetics Immunodominant Epitopes - immunology Libraries Lymphocytes Mice Peptides Reading T cell receptors Virus Diseases - immunology Viruses Viruses - genetics Viruses - immunology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!