Glucocorticoid Regulation of 24-Hour Oscillation in Interferon Receptor Gene Expression in Mouse Liver

Although the antiviral effect of interferon (IFN) varies depending on 24-h oscillation in the expression of its specific receptor, the mechanism of oscillation remains to be clarified. Here we report that oscillation in the expression of the IFN receptor gene (IFN-α/β R1) in mouse liver is caused by...

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Veröffentlicht in:	Endocrinology (Philadelphia) 2006-11, Vol.147 (11), p.5034-5040
Hauptverfasser:	Koyanagi, Satoru, Suyama, Hinako, Kuramoto, Yukako, Matsunaga, Noaya, Takane, Hiroshi, Soeda, Shinji, Shimeno, Hiroshi, Higuchi, Shun, Ohdo, Shigehiro
Format:	Artikel
Sprache:	eng
Schlagworte:	2',5'-Oligoadenylate Synthetase - metabolism Adrenalectomy Animals Antiviral Agents - pharmacology Biological and medical sciences Cells, Cultured Circadian Rhythm Circadian rhythms Corticosterone Corticosterone - pharmacology Feeding Fundamental and applied biological sciences. Psychology Gene expression Gene Expression Regulation - drug effects Glucocorticoid receptors Glucocorticoids Hepatocytes Interferon Interferon-alpha - pharmacology Liver Liver - metabolism Mice Receptor, Interferon alpha-beta - genetics Receptors Rhythm RNA, Messenger - analysis Secretion Time of use Vertebrates: endocrinology α-Interferon
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