Death of a horse infected experimentally with Anaplasma phagocytophilum

A 19-year-old horse that was one of a group of six horses infected experimentally with Anaplasma phagocytophilum for a study of the pathogenesis of equine granulocytic ehrlichiosis died suddenly two days after first showing clinical signs of disease. The clinical signs and laboratory findings observ...

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Veröffentlicht in:Veterinary record 2007-01, Vol.160 (4), p.122-125
Hauptverfasser: Franzén, P., Berg, A-L., Aspan, A., Gunnarsson, A., Pringle, J. D.
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container_end_page 125
container_issue 4
container_start_page 122
container_title Veterinary record
container_volume 160
creator Franzén, P.
Berg, A-L.
Aspan, A.
Gunnarsson, A.
Pringle, J. D.
description A 19-year-old horse that was one of a group of six horses infected experimentally with Anaplasma phagocytophilum for a study of the pathogenesis of equine granulocytic ehrlichiosis died suddenly two days after first showing clinical signs of disease. The clinical signs and laboratory findings observed before its death were similar to all those of the other infected horses, and to previous reports of this disease. A postmortem examination revealed widespread haemorrhaging in its internal organs, and vasculitis and thrombosis in the kidneys. These changes are consistent with disseminated intravascular coagulation, which has previously been reported in human beings infected with the presumably identical agent of human granulocytic ehrlichiosis.
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subjects Anaplasma phagocytophilum
Anaplasma phagocytophilum - pathogenicity
Animals
case studies
Ehrlichiosis - microbiology
Ehrlichiosis - veterinary
Horse Diseases - microbiology
Horses
Male
mortality
title Death of a horse infected experimentally with Anaplasma phagocytophilum
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