Role of the C-terminal di-leucine motif of 5-HT₁A and 5-HT₁B serotonin receptors in plasma membrane targeting

The 5-HT₁A and 5-HT₁B serotonin receptors exhibit different subcellular localizations in neurons. Evidence has been reported that the C-terminal domain is involved in the somato-dendritic and axonal targeting of 5-HT₁AR and 5-HT₁BR, respectively. Here we analyzed the consequences of the mutation of...

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