Cerebral Perfusion
Aortic arch surgery necessitates interrupted brain perfusion and carries a risk of brain injury. Various brain protective techniques have been advocated to reduce risk including hypothermic arrest and retrograde or selective antegrade perfusion. Knowledge of the pathophysiologic consequences of deep...
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Veröffentlicht in: | The Annals of thoracic surgery 2007-02, Vol.83 (2), p.S799-S804 |
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container_title | The Annals of thoracic surgery |
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creator | Harrington, Deborah K., MB, MRCS Fragomeni, Fernanda Bonser, Robert Stuart, MD, FRCS |
description | Aortic arch surgery necessitates interrupted brain perfusion and carries a risk of brain injury. Various brain protective techniques have been advocated to reduce risk including hypothermic arrest and retrograde or selective antegrade perfusion. Knowledge of the pathophysiologic consequences of deep hypothermia, may aid the surgeon in deciding when to initiate circulatory arrest and for how long. Retrograde cerebral perfusion use was advocated to prolong safe arrest durations but may not improve outcomes. Selective antegrade cerebral perfusion appears to have become the preferred method of brain protection. However, the delivery conditions and optimal perfusate constitution require further study. |
doi_str_mv | 10.1016/j.athoracsur.2006.11.018 |
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Various brain protective techniques have been advocated to reduce risk including hypothermic arrest and retrograde or selective antegrade perfusion. Knowledge of the pathophysiologic consequences of deep hypothermia, may aid the surgeon in deciding when to initiate circulatory arrest and for how long. Retrograde cerebral perfusion use was advocated to prolong safe arrest durations but may not improve outcomes. Selective antegrade cerebral perfusion appears to have become the preferred method of brain protection. However, the delivery conditions and optimal perfusate constitution require further study.</description><identifier>ISSN: 0003-4975</identifier><identifier>EISSN: 1552-6259</identifier><identifier>DOI: 10.1016/j.athoracsur.2006.11.018</identifier><identifier>PMID: 17257930</identifier><identifier>CODEN: ATHSAK</identifier><language>eng</language><publisher>New York, NY: Elsevier Inc</publisher><subject>Aorta, Thoracic - surgery ; Axillary Artery ; Biological and medical sciences ; Brain - blood supply ; Cardiothoracic Surgery ; Catheterization ; Heart Arrest, Induced ; Hematocrit ; Humans ; Hypothermia, Induced ; Medical sciences ; Monitoring, Physiologic ; Perfusion - methods ; Surgery ; Surgery (general aspects). Transplantations, organ and tissue grafts. 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Various brain protective techniques have been advocated to reduce risk including hypothermic arrest and retrograde or selective antegrade perfusion. Knowledge of the pathophysiologic consequences of deep hypothermia, may aid the surgeon in deciding when to initiate circulatory arrest and for how long. Retrograde cerebral perfusion use was advocated to prolong safe arrest durations but may not improve outcomes. Selective antegrade cerebral perfusion appears to have become the preferred method of brain protection. However, the delivery conditions and optimal perfusate constitution require further study.</description><subject>Aorta, Thoracic - surgery</subject><subject>Axillary Artery</subject><subject>Biological and medical sciences</subject><subject>Brain - blood supply</subject><subject>Cardiothoracic Surgery</subject><subject>Catheterization</subject><subject>Heart Arrest, Induced</subject><subject>Hematocrit</subject><subject>Humans</subject><subject>Hypothermia, Induced</subject><subject>Medical sciences</subject><subject>Monitoring, Physiologic</subject><subject>Perfusion - methods</subject><subject>Surgery</subject><subject>Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases</subject><subject>Surgery of the heart</subject><subject>Surgery of the respiratory system</subject><subject>Vascular Surgical Procedures</subject><issn>0003-4975</issn><issn>1552-6259</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2007</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkU1LxDAQhoMoun5c_AHiRW-tk2STtBdBF79AUFDPIZ1OMWu31WQr-O9N2YUFT57CkGfeGZ5h7JRDzoHri3nulu99cBiHkAsAnXOeAy-22IQrJTItVLnNJgAgs2lp1B7bj3GeSpG-d9keN0KZUsKEHc8oUBVce_pMoRmi77tDttO4NtLR-j1gb7c3r7P77PHp7mF29ZihmsplpgtudGHK0iECIurSCNkY1SCawijd1LKWVUF1VSkuBZSFAqjAaedq5yotD9j5Kvcz9F8DxaVd-IjUtq6jfohWF6WaCsETWKxADH2MgRr7GfzChR_LwY4-7NxufNjRh-XcJh-p9WQ9Y6gWVG8a1wIScLYGXETXNsF16OOGS0tzo8ag6xVHyci3p2AjeuqQah8Il7bu_X-2ufwTgq3vfJr7QT8U5_0QumTcchuFBfsy3m88H2gQQoup_AXP-paQ</recordid><startdate>20070201</startdate><enddate>20070201</enddate><creator>Harrington, Deborah K., MB, MRCS</creator><creator>Fragomeni, Fernanda</creator><creator>Bonser, Robert Stuart, MD, FRCS</creator><general>Elsevier Inc</general><general>Elsevier Science</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20070201</creationdate><title>Cerebral Perfusion</title><author>Harrington, Deborah K., MB, MRCS ; Fragomeni, Fernanda ; Bonser, Robert Stuart, MD, FRCS</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c543t-681768799acc0ccc69723f75fcc78756fd3d3b8edbb5132098500b0a6aadaab63</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2007</creationdate><topic>Aorta, Thoracic - surgery</topic><topic>Axillary Artery</topic><topic>Biological and medical sciences</topic><topic>Brain - blood supply</topic><topic>Cardiothoracic Surgery</topic><topic>Catheterization</topic><topic>Heart Arrest, Induced</topic><topic>Hematocrit</topic><topic>Humans</topic><topic>Hypothermia, Induced</topic><topic>Medical sciences</topic><topic>Monitoring, Physiologic</topic><topic>Perfusion - methods</topic><topic>Surgery</topic><topic>Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases</topic><topic>Surgery of the heart</topic><topic>Surgery of the respiratory system</topic><topic>Vascular Surgical Procedures</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Harrington, Deborah K., MB, MRCS</creatorcontrib><creatorcontrib>Fragomeni, Fernanda</creatorcontrib><creatorcontrib>Bonser, Robert Stuart, MD, FRCS</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The Annals of thoracic surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Harrington, Deborah K., MB, MRCS</au><au>Fragomeni, Fernanda</au><au>Bonser, Robert Stuart, MD, FRCS</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Cerebral Perfusion</atitle><jtitle>The Annals of thoracic surgery</jtitle><addtitle>Ann Thorac Surg</addtitle><date>2007-02-01</date><risdate>2007</risdate><volume>83</volume><issue>2</issue><spage>S799</spage><epage>S804</epage><pages>S799-S804</pages><issn>0003-4975</issn><eissn>1552-6259</eissn><coden>ATHSAK</coden><abstract>Aortic arch surgery necessitates interrupted brain perfusion and carries a risk of brain injury. Various brain protective techniques have been advocated to reduce risk including hypothermic arrest and retrograde or selective antegrade perfusion. Knowledge of the pathophysiologic consequences of deep hypothermia, may aid the surgeon in deciding when to initiate circulatory arrest and for how long. Retrograde cerebral perfusion use was advocated to prolong safe arrest durations but may not improve outcomes. Selective antegrade cerebral perfusion appears to have become the preferred method of brain protection. However, the delivery conditions and optimal perfusate constitution require further study.</abstract><cop>New York, NY</cop><pub>Elsevier Inc</pub><pmid>17257930</pmid><doi>10.1016/j.athoracsur.2006.11.018</doi><oa>free_for_read</oa></addata></record> |
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subjects | Aorta, Thoracic - surgery Axillary Artery Biological and medical sciences Brain - blood supply Cardiothoracic Surgery Catheterization Heart Arrest, Induced Hematocrit Humans Hypothermia, Induced Medical sciences Monitoring, Physiologic Perfusion - methods Surgery Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Surgery of the heart Surgery of the respiratory system Vascular Surgical Procedures |
title | Cerebral Perfusion |
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