Cerebral Perfusion

Aortic arch surgery necessitates interrupted brain perfusion and carries a risk of brain injury. Various brain protective techniques have been advocated to reduce risk including hypothermic arrest and retrograde or selective antegrade perfusion. Knowledge of the pathophysiologic consequences of deep...

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Veröffentlicht in:The Annals of thoracic surgery 2007-02, Vol.83 (2), p.S799-S804
Hauptverfasser: Harrington, Deborah K., MB, MRCS, Fragomeni, Fernanda, Bonser, Robert Stuart, MD, FRCS
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container_title The Annals of thoracic surgery
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creator Harrington, Deborah K., MB, MRCS
Fragomeni, Fernanda
Bonser, Robert Stuart, MD, FRCS
description Aortic arch surgery necessitates interrupted brain perfusion and carries a risk of brain injury. Various brain protective techniques have been advocated to reduce risk including hypothermic arrest and retrograde or selective antegrade perfusion. Knowledge of the pathophysiologic consequences of deep hypothermia, may aid the surgeon in deciding when to initiate circulatory arrest and for how long. Retrograde cerebral perfusion use was advocated to prolong safe arrest durations but may not improve outcomes. Selective antegrade cerebral perfusion appears to have become the preferred method of brain protection. However, the delivery conditions and optimal perfusate constitution require further study.
doi_str_mv 10.1016/j.athoracsur.2006.11.018
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Graft diseases</topic><topic>Surgery of the heart</topic><topic>Surgery of the respiratory system</topic><topic>Vascular Surgical Procedures</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Harrington, Deborah K., MB, MRCS</creatorcontrib><creatorcontrib>Fragomeni, Fernanda</creatorcontrib><creatorcontrib>Bonser, Robert Stuart, MD, FRCS</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The Annals of thoracic surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Harrington, Deborah K., MB, MRCS</au><au>Fragomeni, Fernanda</au><au>Bonser, Robert Stuart, MD, FRCS</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Cerebral Perfusion</atitle><jtitle>The Annals of thoracic surgery</jtitle><addtitle>Ann Thorac Surg</addtitle><date>2007-02-01</date><risdate>2007</risdate><volume>83</volume><issue>2</issue><spage>S799</spage><epage>S804</epage><pages>S799-S804</pages><issn>0003-4975</issn><eissn>1552-6259</eissn><coden>ATHSAK</coden><abstract>Aortic arch surgery necessitates interrupted brain perfusion and carries a risk of brain injury. 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source MEDLINE; EZB-FREE-00999 freely available EZB journals; Alma/SFX Local Collection
subjects Aorta, Thoracic - surgery
Axillary Artery
Biological and medical sciences
Brain - blood supply
Cardiothoracic Surgery
Catheterization
Heart Arrest, Induced
Hematocrit
Humans
Hypothermia, Induced
Medical sciences
Monitoring, Physiologic
Perfusion - methods
Surgery
Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases
Surgery of the heart
Surgery of the respiratory system
Vascular Surgical Procedures
title Cerebral Perfusion
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