Glucosamine modulates chondrocyte proliferation, matrix synthesis, and gene expression

Summary Objective To investigate the effects of glucosamine (GlcN) on chondrocyte proliferation, matrix production, and gene expression for providing insights into the biochemical basis of its reported beneficial effects in osteoarthritis (OA). Methods Dose-dependent effect of GlcN on cell morpholog...

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Veröffentlicht in:	Osteoarthritis and cartilage 2007-01, Vol.15 (1), p.59-68
Hauptverfasser:	Varghese, S., Ph.D, Theprungsirikul, P., B.S, Sahani, S., B.S, Hwang, N., B.S, Yarema, K.J., Ph.D, Elisseeff, J.H., Ph.D
Format:	Artikel
Sprache:	eng
Schlagworte:	Aggrecans Animals Cartilage repair Cartilage, Articular - cytology Cattle Cell Proliferation - drug effects Chondrocytes - cytology Chondrocytes - drug effects Extracellular Matrix - physiology Gene Expression - drug effects Glucosamine Glucosamine - pharmacology Hydrogels Osteoarthritis Polymerase Chain Reaction Rheumatology
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