Acute effects of immediate and controlled-release levodopa on mood in Parkinson's disease: A double-blind study

Mood fluctuations related to levodopa (LD) dosing are well‐known psychiatric complications of Parkinson's disease (PD). No formal studies explored how affective response to LD relates to the type of motor response to oral LD (stable or wearing‐off) and to different pharmacokinetic profiles of o...

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Veröffentlicht in:	Movement disorders 2007-01, Vol.22 (1), p.62-67
Hauptverfasser:	Kulisevsky, Jaime, Pascual-Sedano, Berta, Barbanoj, Manel, Gironell, Alexandre, Pagonabarraga, Javier, García-Sánchez, Carmen
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Oral Affect - drug effects Aged Antiparkinson Agents - administration & dosage Antiparkinson Agents - blood anxiety Anxiety - drug therapy Anxiety - etiology Biological and medical sciences Case-Control Studies Cross-Over Studies Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases dopamine Double-Blind Method Drug toxicity and drugs side effects treatment Female Headache. Facial pains. Syncopes. Epilepsia. Intracranial hypertension. Brain oedema. Cerebral palsy Humans levodopa Levodopa - administration & dosage Levodopa - blood Male Medical sciences Middle Aged mood Nervous system (semeiology, syndromes) Neurology Pain Measurement Parkinson Disease - blood Parkinson Disease - drug therapy Parkinson Disease - physiopathology Parkinson's disease Pharmacology. Drug treatments Time Factors Toxicity: nervous system and muscle
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