On the Seeding and Oligomerization of pGlu-Amyloid Peptides (in vitro)

Oligomerization of amyloid β (Aβ) peptides is the decisive event in the development of Alzheimer's disease (AD), the most common neurogenerative disorder in developed countries. Recent evidence links this conformation-driven process to primary- and secondary-structure modifications of Aβ. The N...

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Veröffentlicht in:	Biochemistry (Easton) 2006-10, Vol.45 (41), p.12393-12399
Hauptverfasser:	Schilling, Stephan, Lauber, Thomas, Schaupp, Michael, Manhart, Susanne, Scheel, Eike, Böhm, Gerald, Demuth, Hans-Ulrich
Format:	Artikel
Sprache:	eng
Schlagworte:	Amyloid beta-Peptides - chemical synthesis Amyloid beta-Peptides - chemistry Flow Cytometry Fluorescent Dyes Humans In Vitro Techniques Peptide Fragments - chemical synthesis Peptide Fragments - chemistry Protein Structure, Quaternary Pyrrolidonecarboxylic Acid - chemistry Thiazoles
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