Morpheus Unbound: Reimagining the Morphogen Gradient

The theory that the spatial organization of cell fate is orchestrated by gradients of diffusing molecules was a major contribution to 20 th century developmental biology. Although the existence of morphogens is no longer in doubt, studies on the formation and function of their gradients have yielded...

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Veröffentlicht in:	Cell 2007-01, Vol.128 (2), p.245-256
1. Verfasser:	Lander, Arthur D.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Body Patterning - physiology Diffusion Embryo, Mammalian - cytology Embryo, Mammalian - metabolism Gene Expression Regulation, Developmental - physiology Humans Intercellular Signaling Peptides and Proteins - genetics Intercellular Signaling Peptides and Proteins - metabolism Models, Biological Morphogenesis - physiology Signal Transduction - physiology Systems Biology - methods Systems Biology - trends
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