Uterine-Artery Embolization versus Surgery for Symptomatic Uterine Fibroids
In this multicenter, randomized trial of outcomes of uterine-artery embolization versus surgery for symptomatic fibroids, there were no differences between groups in quality of life at 1 year. Women who underwent embolization had a shorter duration of hospitalization and a shorter interval until the...
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Veröffentlicht in: | The New England journal of medicine 2007-01, Vol.356 (4), p.360-370 |
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creator | Edwards, Richard D Moss, Jonathan G Lumsden, Mary Ann Wu, Olivia Murray, Lilian S Twaddle, Sara Murray, Gordon D |
description | In this multicenter, randomized trial of outcomes of uterine-artery embolization versus surgery for symptomatic fibroids, there were no differences between groups in quality of life at 1 year. Women who underwent embolization had a shorter duration of hospitalization and a shorter interval until the resumption of normal activities but were more likely to require rehospitalization for adverse outcomes or to need reintervention owing to treatment failure.
Women who underwent embolization had a shorter duration of hospitalization but were more likely to require rehospitalization for adverse outcomes or to need reintervention owing to treatment failure.
Uterine fibroids are the most common type of tumor in the female reproductive system. The presence of these tumors may cause menstrual disorder and can be associated with subfertility, miscarriage, and pressure effects.
1
For women who no longer plan to give birth, the established treatment is hysterectomy. In the United Kingdom, approximately 42,500 hysterectomies are performed annually, with approximately 30% indicated for fibroids (the second-most-frequent indication).
2
For women wishing to maintain their fertility, myomectomy is the principal option.
Uterine-artery embolization was introduced in 1995 as an alternative technique for treating fibroids.
3
Since then it has become increasingly accepted as a . . . |
doi_str_mv | 10.1056/NEJMoa062003 |
format | Article |
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Women who underwent embolization had a shorter duration of hospitalization but were more likely to require rehospitalization for adverse outcomes or to need reintervention owing to treatment failure.
Uterine fibroids are the most common type of tumor in the female reproductive system. The presence of these tumors may cause menstrual disorder and can be associated with subfertility, miscarriage, and pressure effects.
1
For women who no longer plan to give birth, the established treatment is hysterectomy. In the United Kingdom, approximately 42,500 hysterectomies are performed annually, with approximately 30% indicated for fibroids (the second-most-frequent indication).
2
For women wishing to maintain their fertility, myomectomy is the principal option.
Uterine-artery embolization was introduced in 1995 as an alternative technique for treating fibroids.
3
Since then it has become increasingly accepted as a . . .</description><identifier>ISSN: 0028-4793</identifier><identifier>EISSN: 1533-4406</identifier><identifier>DOI: 10.1056/NEJMoa062003</identifier><identifier>PMID: 17251532</identifier><identifier>CODEN: NEJMAG</identifier><language>eng</language><publisher>Boston, MA: Massachusetts Medical Society</publisher><subject>Adult ; Biological and medical sciences ; Embolization, Therapeutic - adverse effects ; Embolization, Therapeutic - economics ; Female ; Female genital diseases ; Fibroids ; Follow-Up Studies ; General aspects ; Gynecology. Andrology. Obstetrics ; Humans ; Hysterectomy ; Hysterectomy - economics ; Leiomyoma - surgery ; Leiomyoma - therapy ; Length of Stay ; Medical sciences ; NMR ; Nuclear magnetic resonance ; Postoperative Complications ; Quality of Life ; Reoperation ; Reproductive system ; Treatment Failure ; Tumors ; Uterine Neoplasms - surgery ; Uterine Neoplasms - therapy ; Womens health</subject><ispartof>The New England journal of medicine, 2007-01, Vol.356 (4), p.360-370</ispartof><rights>Copyright © 2007 Massachusetts Medical Society. All rights reserved.</rights><rights>2007 INIST-CNRS</rights><rights>Copyright 2007 Massachusetts Medical Society.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c500t-c4064f5faf0aceefb71b348b7d9ba7ced5739570156154016bea39669627127f3</citedby><cites>FETCH-LOGICAL-c500t-c4064f5faf0aceefb71b348b7d9ba7ced5739570156154016bea39669627127f3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.nejm.org/doi/pdf/10.1056/NEJMoa062003$$EPDF$$P50$$Gmms$$H</linktopdf><linktohtml>$$Uhttps://www.nejm.org/doi/full/10.1056/NEJMoa062003$$EHTML$$P50$$Gmms$$H</linktohtml><link.rule.ids>314,776,780,2746,2747,26080,27901,27902,52357,54039</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=18466680$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/17251532$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Edwards, Richard D</creatorcontrib><creatorcontrib>Moss, Jonathan G</creatorcontrib><creatorcontrib>Lumsden, Mary Ann</creatorcontrib><creatorcontrib>Wu, Olivia</creatorcontrib><creatorcontrib>Murray, Lilian S</creatorcontrib><creatorcontrib>Twaddle, Sara</creatorcontrib><creatorcontrib>Murray, Gordon D</creatorcontrib><creatorcontrib>The REST Investigators</creatorcontrib><creatorcontrib>Committee of the Randomized Trial of Embolization versus Surgical Treatment for Fibroids</creatorcontrib><title>Uterine-Artery Embolization versus Surgery for Symptomatic Uterine Fibroids</title><title>The New England journal of medicine</title><addtitle>N Engl J Med</addtitle><description>In this multicenter, randomized trial of outcomes of uterine-artery embolization versus surgery for symptomatic fibroids, there were no differences between groups in quality of life at 1 year. Women who underwent embolization had a shorter duration of hospitalization and a shorter interval until the resumption of normal activities but were more likely to require rehospitalization for adverse outcomes or to need reintervention owing to treatment failure.
Women who underwent embolization had a shorter duration of hospitalization but were more likely to require rehospitalization for adverse outcomes or to need reintervention owing to treatment failure.
Uterine fibroids are the most common type of tumor in the female reproductive system. The presence of these tumors may cause menstrual disorder and can be associated with subfertility, miscarriage, and pressure effects.
1
For women who no longer plan to give birth, the established treatment is hysterectomy. In the United Kingdom, approximately 42,500 hysterectomies are performed annually, with approximately 30% indicated for fibroids (the second-most-frequent indication).
2
For women wishing to maintain their fertility, myomectomy is the principal option.
Uterine-artery embolization was introduced in 1995 as an alternative technique for treating fibroids.
3
Since then it has become increasingly accepted as a . . .</description><subject>Adult</subject><subject>Biological and medical sciences</subject><subject>Embolization, Therapeutic - adverse effects</subject><subject>Embolization, Therapeutic - economics</subject><subject>Female</subject><subject>Female genital diseases</subject><subject>Fibroids</subject><subject>Follow-Up Studies</subject><subject>General aspects</subject><subject>Gynecology. Andrology. Obstetrics</subject><subject>Humans</subject><subject>Hysterectomy</subject><subject>Hysterectomy - economics</subject><subject>Leiomyoma - surgery</subject><subject>Leiomyoma - therapy</subject><subject>Length of Stay</subject><subject>Medical sciences</subject><subject>NMR</subject><subject>Nuclear magnetic resonance</subject><subject>Postoperative Complications</subject><subject>Quality of Life</subject><subject>Reoperation</subject><subject>Reproductive system</subject><subject>Treatment Failure</subject><subject>Tumors</subject><subject>Uterine Neoplasms - surgery</subject><subject>Uterine Neoplasms - therapy</subject><subject>Womens health</subject><issn>0028-4793</issn><issn>1533-4406</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2007</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BEC</sourceid><sourceid>BENPR</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNpt0ElLxDAUB_Agio7LzbMUUU9Ws6c5DjLuy2H0XNJMIh2aZkxaYfz0ZpiCIuaSwPvlvccfgEMELxBk_PJ5cv_kFeQYQrIBRogRklMK-SYYQYiLnApJdsBujHOYDqJyG-wggVmCeAQe3joT6tbk45Aey2ziKt_UX6qrfZt9mhD7mE378L6qWR-y6dItOu9SXWfD1-y6roKvZ3EfbFnVRHMw3Hvg7XryenWbP77c3F2NH3PNIOxynZajllllodLG2EqgitCiEjNZKaHNjAkimYCIccQoRLwyikjOJccCYWHJHjhb910E_9Gb2JWujto0jWqN72PJC0kJwjLB4z9w7vvQpt1KjInERYFFQudrpIOPMRhbLkLtVFiWCJarhMvfCSd-NPTsK2dmP3iINIHTAaioVWODanUdf1xBOecFTO5k7ZyLZWvm7v9535fNjeA</recordid><startdate>20070125</startdate><enddate>20070125</enddate><creator>Edwards, Richard D</creator><creator>Moss, Jonathan G</creator><creator>Lumsden, Mary Ann</creator><creator>Wu, Olivia</creator><creator>Murray, Lilian S</creator><creator>Twaddle, Sara</creator><creator>Murray, Gordon D</creator><general>Massachusetts Medical Society</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>0TZ</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>8AO</scope><scope>8C1</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AN0</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BEC</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>HCIFZ</scope><scope>K0Y</scope><scope>LK8</scope><scope>M0R</scope><scope>M0T</scope><scope>M1P</scope><scope>M2M</scope><scope>M2O</scope><scope>M2P</scope><scope>M7P</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PSYQQ</scope><scope>Q9U</scope><scope>7X8</scope></search><sort><creationdate>20070125</creationdate><title>Uterine-Artery Embolization versus Surgery for Symptomatic Uterine Fibroids</title><author>Edwards, Richard D ; Moss, Jonathan G ; Lumsden, Mary Ann ; Wu, Olivia ; Murray, Lilian S ; Twaddle, Sara ; Murray, Gordon D</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c500t-c4064f5faf0aceefb71b348b7d9ba7ced5739570156154016bea39669627127f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2007</creationdate><topic>Adult</topic><topic>Biological and medical sciences</topic><topic>Embolization, Therapeutic - adverse effects</topic><topic>Embolization, Therapeutic - economics</topic><topic>Female</topic><topic>Female genital diseases</topic><topic>Fibroids</topic><topic>Follow-Up Studies</topic><topic>General aspects</topic><topic>Gynecology. Andrology. Obstetrics</topic><topic>Humans</topic><topic>Hysterectomy</topic><topic>Hysterectomy - economics</topic><topic>Leiomyoma - surgery</topic><topic>Leiomyoma - therapy</topic><topic>Length of Stay</topic><topic>Medical sciences</topic><topic>NMR</topic><topic>Nuclear magnetic resonance</topic><topic>Postoperative Complications</topic><topic>Quality of Life</topic><topic>Reoperation</topic><topic>Reproductive system</topic><topic>Treatment Failure</topic><topic>Tumors</topic><topic>Uterine Neoplasms - surgery</topic><topic>Uterine Neoplasms - therapy</topic><topic>Womens health</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Edwards, Richard D</creatorcontrib><creatorcontrib>Moss, Jonathan G</creatorcontrib><creatorcontrib>Lumsden, Mary Ann</creatorcontrib><creatorcontrib>Wu, Olivia</creatorcontrib><creatorcontrib>Murray, Lilian S</creatorcontrib><creatorcontrib>Twaddle, Sara</creatorcontrib><creatorcontrib>Murray, Gordon D</creatorcontrib><creatorcontrib>The REST Investigators</creatorcontrib><creatorcontrib>Committee of the Randomized Trial of Embolization versus Surgical Treatment for Fibroids</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Pharma and Biotech Premium PRO</collection><collection>Nursing & Allied Health Database</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>British Nursing Database</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>eLibrary</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>SciTech Premium Collection</collection><collection>New England Journal of Medicine</collection><collection>ProQuest Biological Science Collection</collection><collection>Consumer Health Database</collection><collection>Healthcare Administration Database</collection><collection>Medical Database</collection><collection>Psychology Database</collection><collection>Research Library</collection><collection>Science Database</collection><collection>Biological Science Database</collection><collection>Research Library (Corporate)</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest One Psychology</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><jtitle>The New England journal of medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Edwards, Richard D</au><au>Moss, Jonathan G</au><au>Lumsden, Mary Ann</au><au>Wu, Olivia</au><au>Murray, Lilian S</au><au>Twaddle, Sara</au><au>Murray, Gordon D</au><aucorp>The REST Investigators</aucorp><aucorp>Committee of the Randomized Trial of Embolization versus Surgical Treatment for Fibroids</aucorp><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Uterine-Artery Embolization versus Surgery for Symptomatic Uterine Fibroids</atitle><jtitle>The New England journal of medicine</jtitle><addtitle>N Engl J Med</addtitle><date>2007-01-25</date><risdate>2007</risdate><volume>356</volume><issue>4</issue><spage>360</spage><epage>370</epage><pages>360-370</pages><issn>0028-4793</issn><eissn>1533-4406</eissn><coden>NEJMAG</coden><abstract>In this multicenter, randomized trial of outcomes of uterine-artery embolization versus surgery for symptomatic fibroids, there were no differences between groups in quality of life at 1 year. Women who underwent embolization had a shorter duration of hospitalization and a shorter interval until the resumption of normal activities but were more likely to require rehospitalization for adverse outcomes or to need reintervention owing to treatment failure.
Women who underwent embolization had a shorter duration of hospitalization but were more likely to require rehospitalization for adverse outcomes or to need reintervention owing to treatment failure.
Uterine fibroids are the most common type of tumor in the female reproductive system. The presence of these tumors may cause menstrual disorder and can be associated with subfertility, miscarriage, and pressure effects.
1
For women who no longer plan to give birth, the established treatment is hysterectomy. In the United Kingdom, approximately 42,500 hysterectomies are performed annually, with approximately 30% indicated for fibroids (the second-most-frequent indication).
2
For women wishing to maintain their fertility, myomectomy is the principal option.
Uterine-artery embolization was introduced in 1995 as an alternative technique for treating fibroids.
3
Since then it has become increasingly accepted as a . . .</abstract><cop>Boston, MA</cop><pub>Massachusetts Medical Society</pub><pmid>17251532</pmid><doi>10.1056/NEJMoa062003</doi><tpages>11</tpages><oa>free_for_read</oa></addata></record> |
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source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; New England Journal of Medicine |
subjects | Adult Biological and medical sciences Embolization, Therapeutic - adverse effects Embolization, Therapeutic - economics Female Female genital diseases Fibroids Follow-Up Studies General aspects Gynecology. Andrology. Obstetrics Humans Hysterectomy Hysterectomy - economics Leiomyoma - surgery Leiomyoma - therapy Length of Stay Medical sciences NMR Nuclear magnetic resonance Postoperative Complications Quality of Life Reoperation Reproductive system Treatment Failure Tumors Uterine Neoplasms - surgery Uterine Neoplasms - therapy Womens health |
title | Uterine-Artery Embolization versus Surgery for Symptomatic Uterine Fibroids |
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