Associations between promoter usage and alternative splicing of the glucocorticoid receptor gene

The glucocorticoid receptor (GR) is widely expressed in various tissues throughout the human body. At least three different 3′-splice variants of the GR have been reported: GR-α, which is functionally active; GR-β, which is a dominant negative inhibitor of GR-α function; and GR-P, which is thought t...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Journal of molecular endocrinology 2007-02, Vol.38 (1), p.91-98
Hauptverfasser:	Russcher, Henk, Dalm, Virgil A S H, de Jong, Frank H, Brinkmann, Albert O, Hofland, Leo J, Lamberts, Steven W J, Koper, Jan W
Format:	Artikel
Sprache:	eng
Schlagworte:	Alternative Splicing - genetics Cell Line, Transformed Exons Gene Expression Regulation - physiology Humans Organ Specificity Promoter Regions, Genetic Protein Isoforms - biosynthesis Protein Isoforms - genetics Receptors, Glucocorticoid - biosynthesis Receptors, Glucocorticoid - genetics Regular papers
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!