Principal Components Analysis of Obsessive–Compulsive Disorder Symptoms in Children and Adolescents

Background Obsessive–compulsive disorder (OCD) has a broadly diverse clinical expression that may reflect etiologic heterogeneity. Several adult studies have identified consistent symptom dimensions of OCD. The purpose of this study was to conduct an exploratory principal components analysis of obse...

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Veröffentlicht in:Biological psychiatry (1969) 2007-02, Vol.61 (3), p.285-291
Hauptverfasser: Stewart, S. Evelyn, Rosario, Maria C, Brown, Timothy A, Carter, Alice S, Leckman, James F, Sukhodolsky, Denis, Katsovitch, Liliya, King, Robert, Geller, Daniel, Pauls, David L
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container_end_page 291
container_issue 3
container_start_page 285
container_title Biological psychiatry (1969)
container_volume 61
creator Stewart, S. Evelyn
Rosario, Maria C
Brown, Timothy A
Carter, Alice S
Leckman, James F
Sukhodolsky, Denis
Katsovitch, Liliya
King, Robert
Geller, Daniel
Pauls, David L
description Background Obsessive–compulsive disorder (OCD) has a broadly diverse clinical expression that may reflect etiologic heterogeneity. Several adult studies have identified consistent symptom dimensions of OCD. The purpose of this study was to conduct an exploratory principal components analysis of obsessive–compulsive (OC) symptoms in children and adolescents with OCD to identify improved phenotypes for future studies. Methods This study examined lifetime occurrence of OC symptoms included in the 13 symptom categories of the Yale–Brown Obsessive Compulsive Scale (Y-BOCS) and the Children’s Yale-Brown Obsessive–Compulsive Scale (CY-BOCS). Principal components analysis with promax rotation was performed on 231 children and adolescents with OCD and compared with results of similar adult studies. Results A four-factor solution emerged explaining 59.8% of symptom variance characterized by 1) symmetry/ordering/repeating/checking; 2) contamination/cleaning/aggressive/somatic; 3) hoarding; and 4) sexual/religious symptoms. All factors included core symptoms that have been consistently observed in adult studies of OCD. Conclusions In children and adolescents, OCD is a multidimensional disorder. Symptom dimensions are predominantly congruent with those described in similar studies of adults with OCD, suggesting fairly consistent covariation of OCD symptoms through the developmental course. Future work is required to understand changes in specific symptom dimensions observed across the life span.
doi_str_mv 10.1016/j.biopsych.2006.08.040
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Evelyn ; Rosario, Maria C ; Brown, Timothy A ; Carter, Alice S ; Leckman, James F ; Sukhodolsky, Denis ; Katsovitch, Liliya ; King, Robert ; Geller, Daniel ; Pauls, David L</creator><creatorcontrib>Stewart, S. Evelyn ; Rosario, Maria C ; Brown, Timothy A ; Carter, Alice S ; Leckman, James F ; Sukhodolsky, Denis ; Katsovitch, Liliya ; King, Robert ; Geller, Daniel ; Pauls, David L</creatorcontrib><description>Background Obsessive–compulsive disorder (OCD) has a broadly diverse clinical expression that may reflect etiologic heterogeneity. Several adult studies have identified consistent symptom dimensions of OCD. The purpose of this study was to conduct an exploratory principal components analysis of obsessive–compulsive (OC) symptoms in children and adolescents with OCD to identify improved phenotypes for future studies. Methods This study examined lifetime occurrence of OC symptoms included in the 13 symptom categories of the Yale–Brown Obsessive Compulsive Scale (Y-BOCS) and the Children’s Yale-Brown Obsessive–Compulsive Scale (CY-BOCS). Principal components analysis with promax rotation was performed on 231 children and adolescents with OCD and compared with results of similar adult studies. Results A four-factor solution emerged explaining 59.8% of symptom variance characterized by 1) symmetry/ordering/repeating/checking; 2) contamination/cleaning/aggressive/somatic; 3) hoarding; and 4) sexual/religious symptoms. All factors included core symptoms that have been consistently observed in adult studies of OCD. Conclusions In children and adolescents, OCD is a multidimensional disorder. Symptom dimensions are predominantly congruent with those described in similar studies of adults with OCD, suggesting fairly consistent covariation of OCD symptoms through the developmental course. 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Evelyn</creatorcontrib><creatorcontrib>Rosario, Maria C</creatorcontrib><creatorcontrib>Brown, Timothy A</creatorcontrib><creatorcontrib>Carter, Alice S</creatorcontrib><creatorcontrib>Leckman, James F</creatorcontrib><creatorcontrib>Sukhodolsky, Denis</creatorcontrib><creatorcontrib>Katsovitch, Liliya</creatorcontrib><creatorcontrib>King, Robert</creatorcontrib><creatorcontrib>Geller, Daniel</creatorcontrib><creatorcontrib>Pauls, David L</creatorcontrib><title>Principal Components Analysis of Obsessive–Compulsive Disorder Symptoms in Children and Adolescents</title><title>Biological psychiatry (1969)</title><addtitle>Biol Psychiatry</addtitle><description>Background Obsessive–compulsive disorder (OCD) has a broadly diverse clinical expression that may reflect etiologic heterogeneity. Several adult studies have identified consistent symptom dimensions of OCD. The purpose of this study was to conduct an exploratory principal components analysis of obsessive–compulsive (OC) symptoms in children and adolescents with OCD to identify improved phenotypes for future studies. Methods This study examined lifetime occurrence of OC symptoms included in the 13 symptom categories of the Yale–Brown Obsessive Compulsive Scale (Y-BOCS) and the Children’s Yale-Brown Obsessive–Compulsive Scale (CY-BOCS). Principal components analysis with promax rotation was performed on 231 children and adolescents with OCD and compared with results of similar adult studies. Results A four-factor solution emerged explaining 59.8% of symptom variance characterized by 1) symmetry/ordering/repeating/checking; 2) contamination/cleaning/aggressive/somatic; 3) hoarding; and 4) sexual/religious symptoms. All factors included core symptoms that have been consistently observed in adult studies of OCD. Conclusions In children and adolescents, OCD is a multidimensional disorder. Symptom dimensions are predominantly congruent with those described in similar studies of adults with OCD, suggesting fairly consistent covariation of OCD symptoms through the developmental course. 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Evelyn</creatorcontrib><creatorcontrib>Rosario, Maria C</creatorcontrib><creatorcontrib>Brown, Timothy A</creatorcontrib><creatorcontrib>Carter, Alice S</creatorcontrib><creatorcontrib>Leckman, James F</creatorcontrib><creatorcontrib>Sukhodolsky, Denis</creatorcontrib><creatorcontrib>Katsovitch, Liliya</creatorcontrib><creatorcontrib>King, Robert</creatorcontrib><creatorcontrib>Geller, Daniel</creatorcontrib><creatorcontrib>Pauls, David L</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Neurosciences Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Biological psychiatry (1969)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Stewart, S. Evelyn</au><au>Rosario, Maria C</au><au>Brown, Timothy A</au><au>Carter, Alice S</au><au>Leckman, James F</au><au>Sukhodolsky, Denis</au><au>Katsovitch, Liliya</au><au>King, Robert</au><au>Geller, Daniel</au><au>Pauls, David L</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Principal Components Analysis of Obsessive–Compulsive Disorder Symptoms in Children and Adolescents</atitle><jtitle>Biological psychiatry (1969)</jtitle><addtitle>Biol Psychiatry</addtitle><date>2007-02-01</date><risdate>2007</risdate><volume>61</volume><issue>3</issue><spage>285</spage><epage>291</epage><pages>285-291</pages><issn>0006-3223</issn><eissn>1873-2402</eissn><abstract>Background Obsessive–compulsive disorder (OCD) has a broadly diverse clinical expression that may reflect etiologic heterogeneity. Several adult studies have identified consistent symptom dimensions of OCD. 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subjects Adolescent
Adolescents
Age Factors
Aggression - psychology
Child
children
dimension
factor
Female
Humans
Male
Obsessive-Compulsive Disorder - epidemiology
obsessive–compulsive disorder
phenomenology
Phenotype
Principal Component Analysis
Psychiatric Status Rating Scales
Psychiatry
Sex Factors
Sexual Behavior
title Principal Components Analysis of Obsessive–Compulsive Disorder Symptoms in Children and Adolescents
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