Spontaneous, homeostatic, and inflammation-induced sleep in NF-kappaB p50 knockout mice

The dimeric transcription factor nuclear factor-kappaB (NF-kappaB) regulates several endogenous sleep-modulatory substances and thereby serves as a pivotal mediator of sleep-wake homeostasis. To further define the role of NF-kappaB in sleep regulation, we monitored sleep and temperature in mice that...

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Veröffentlicht in:	American journal of physiology. Regulatory, integrative and comparative physiology integrative and comparative physiology, 2006-11, Vol.291 (5), p.R1516-R1526
Hauptverfasser:	Jhaveri, K A, Ramkumar, V, Trammell, R A, Toth, L A
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Body Temperature - drug effects Body Temperature - genetics Body Temperature - physiology Drinking - genetics Drinking - physiology Eating - genetics Eating - physiology Homeostasis - genetics Homeostasis - physiology Inflammation - genetics Inflammation - physiopathology Lipopolysaccharides - pharmacology Male Mice Mice, Knockout NF-kappa B - genetics NF-kappa B - physiology Orthomyxoviridae - pathogenicity Protein Subunits - genetics Protein Subunits - physiology Sleep - drug effects Sleep - genetics Sleep - physiology Sleep, REM - genetics Sleep, REM - physiology Wakefulness - genetics Wakefulness - physiology
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