Contribution of Interferon-β to the Murine Macrophage Response to the Toll-like Receptor 4 Agonist, Lipopolysaccharide

Interferon-β (IFN-β) has been identified as the signature cytokine induced via the Toll-like receptor (TLR) 4, “MyD88-independent” signaling pathway in macrophages stimulated by Gram-negative bacterial lipopolysaccharide (LPS). In this study, we analyzed the responses of macrophages derived from wil...

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Veröffentlicht in:	The Journal of biological chemistry 2006-10, Vol.281 (41), p.31119-31130
Hauptverfasser:	Thomas, Karen E., Galligan, Carole L., Newman, Raj Deonarain, Fish, Eleanor N., Vogel, Stefanie N.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Escherichia coli Escherichia coli - metabolism Interferon-beta - metabolism Lipopolysaccharides - metabolism Macrophages - metabolism Mice Mice, Inbred C57BL Mice, Transgenic Models, Genetic Oligonucleotide Array Sequence Analysis Promoter Regions, Genetic RNA, Messenger - metabolism Toll-Like Receptor 4 - agonists Toll-Like Receptor 4 - physiology
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