Plant Phenolics Inhibit Neutrophil Elastase

Abstract Human neutrophil elastase (HNE) is a serine protease, which is present in its active form in inflamed tissue as well as in psoriatic lesions. In extension of our research on natural compounds as inhibitors of HNE or of its release, several phenolics of different size were tested. The ellagi...

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Veröffentlicht in:	Planta medica 2006-10, Vol.72 (12), p.1127-1131
Hauptverfasser:	Hrenn, A, Steinbrecher, T, Labahn, A, Schwager, J, Schempp, C.M, Merfort, I
Format:	Artikel
Sprache:	eng
Schlagworte:	agrimoniin Biological and medical sciences Catechin - analogs & derivatives Catechin - pharmacology cultured cells elastase enzyme inhibition enzyme inhibitors General pharmacology Genistein - pharmacology Humans Hydrolyzable Tannins - pharmacology Leukocyte Elastase - antagonists & inhibitors Medical sciences neutrophils Original Paper pedunculagin Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments phenolic compounds Phenols - pharmacology Phenylethyl Alcohol - analogs & derivatives Phenylethyl Alcohol - pharmacology Plant Extracts - chemistry plant products Proteinase Inhibitory Proteins, Secretory - analysis Stilbenes - pharmacology structure-activity relationships
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