Calpain Is Required for the Rapid, Calcium-dependent Repair of Wounded Plasma Membrane

Mammalian cells require extracellular calcium ion to undergo rapid plasma membrane repair seconds after mechanical damage. Utilizing transformed fibroblasts from calpain small subunit knock-out (Capns1-/-) mouse embryos, we now show that the heterodimeric, typical subclass of calpains is required fo...

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Veröffentlicht in:	The Journal of biological chemistry 2007-01, Vol.282 (4), p.2567-2575
Hauptverfasser:	Mellgren, Ronald L., Zhang, Wenli, Miyake, Katsuya, McNeil, Paul L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Calcium - physiology Calcium Signaling Calpain - physiology Cell Membrane - physiology Cell Membrane - ultrastructure Cell Survival - physiology Cells, Cultured Humans Lasers Mice Mice, Knockout Stress, Mechanical Talin - physiology Vimentin - physiology
Online-Zugang:	Volltext
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