The Homeopathic Antiarthitic Preparation Zeel comp. N: A Review of Molecular and Clinical Data
Zeel comp. N (Zeel) is a homeopathic medication that has been widely used for many years for the treatment of arthritic disorders in a large number of countries worldwide. In recent years, a growing body of clinical and molecular evidence has been accumulating that shed light on the possible antiart...
Gespeichert in:
| Veröffentlicht in: | Explore (New York, N.Y.) N.Y.), 2007, Vol.3 (1), p.16-22 |
|---|---|
| Hauptverfasser: | , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 22 |
|---|---|
| container_issue | 1 |
| container_start_page | 16 |
| container_title | Explore (New York, N.Y.) |
| container_volume | 3 |
| creator | Birnesser, Heinz Stolt, Pelle |
| description | Zeel comp. N (Zeel) is a homeopathic medication that has been widely used for many years for the treatment of arthritic disorders in a large number of countries worldwide. In recent years, a growing body of clinical and molecular evidence has been accumulating that shed light on the possible antiarthritic effects of this preparation. A number of studies report anti-inflammatory effects from Zeel. In vitro studies have indicated Zeel-mediated inhibition of the pathways involving the enzymes cyclooxygenase-1 and -2, and also the 5-lipoxygenase pathways, affecting levels of both eicosanoids and leukotrienes. Thus, Zeel may reduce the main two classes of molecules responsible for arthritic pain and inflammation. This review describes recent research on Zeel and discusses the need for further studies to clarify the role of the compound in the antiarthritic armamentarium of complementary medicine. |
| doi_str_mv | 10.1016/j.explore.2006.10.002 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_68926890</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S1550830706004526</els_id><sourcerecordid>68926890</sourcerecordid><originalsourceid>FETCH-LOGICAL-c363t-716d1f1e0bb0d4499163dea13d66507f4ce38a2e214770e3b2aa81aa2702f3143</originalsourceid><addsrcrecordid>eNqFkE1v1DAQhi0EoqXwE0A-cUsY24md5YJWS6FIpSBULhywZp2J6pUTBztLy7_Hq12JI4fRfOideTUPYy8F1AKEfrOr6WEOMVEtAXSZ1QDyETsXnekq0zbicanbFqpOgTljz3LeASjdav2UnQkjVdPq5pz9vL0jfhVHijMud97x9bR4TKVcSvM10YwJFx8n_oMocBfHueY3b_maf6Pfnu55HPjnGMjtAyaOU883wU_eYeDvccHn7MmAIdOLU75g3z9c3m6uqusvHz9t1teVU1otlRG6F4Mg2G6hb5rVSmjVEwrVa92CGRpHqkNJUjTGAKmtROwEojQgByUadcFeH-_OKf7aU17s6LOjEHCiuM9WdytZAoqwPQpdijknGuyc_IjpjxVgD2Dtzp7A2gPYw7iALXuvTgb77Uj9v60TySJ4dxRQebOQSTY7T5Oj3idyi-2j_4_FX6ofi2I</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>68926890</pqid></control><display><type>article</type><title>The Homeopathic Antiarthitic Preparation Zeel comp. N: A Review of Molecular and Clinical Data</title><source>MEDLINE</source><source>Elsevier ScienceDirect Journals</source><creator>Birnesser, Heinz ; Stolt, Pelle</creator><creatorcontrib>Birnesser, Heinz ; Stolt, Pelle</creatorcontrib><description>Zeel comp. N (Zeel) is a homeopathic medication that has been widely used for many years for the treatment of arthritic disorders in a large number of countries worldwide. In recent years, a growing body of clinical and molecular evidence has been accumulating that shed light on the possible antiarthritic effects of this preparation. A number of studies report anti-inflammatory effects from Zeel. In vitro studies have indicated Zeel-mediated inhibition of the pathways involving the enzymes cyclooxygenase-1 and -2, and also the 5-lipoxygenase pathways, affecting levels of both eicosanoids and leukotrienes. Thus, Zeel may reduce the main two classes of molecules responsible for arthritic pain and inflammation. This review describes recent research on Zeel and discusses the need for further studies to clarify the role of the compound in the antiarthritic armamentarium of complementary medicine.</description><identifier>ISSN: 1550-8307</identifier><identifier>EISSN: 1878-7541</identifier><identifier>DOI: 10.1016/j.explore.2006.10.002</identifier><identifier>PMID: 17234564</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Anti-Inflammatory Agents, Non-Steroidal - pharmacology ; Anti-Inflammatory Agents, Non-Steroidal - therapeutic use ; Arthritis ; Arthritis - drug therapy ; cyclooxygenases ; Dose-Response Relationship, Drug ; Evidence-Based Medicine ; homeopathy ; Homeopathy - methods ; Humans ; leukotrienes ; Meta-Analysis as Topic ; Plant Extracts - pharmacology ; Plant Extracts - therapeutic use ; prostaglandins ; Randomized Controlled Trials as Topic ; Sulfur Compounds</subject><ispartof>Explore (New York, N.Y.), 2007, Vol.3 (1), p.16-22</ispartof><rights>2007 Elsevier Inc.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c363t-716d1f1e0bb0d4499163dea13d66507f4ce38a2e214770e3b2aa81aa2702f3143</citedby><cites>FETCH-LOGICAL-c363t-716d1f1e0bb0d4499163dea13d66507f4ce38a2e214770e3b2aa81aa2702f3143</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S1550830706004526$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,4010,27900,27901,27902,65306</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/17234564$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Birnesser, Heinz</creatorcontrib><creatorcontrib>Stolt, Pelle</creatorcontrib><title>The Homeopathic Antiarthitic Preparation Zeel comp. N: A Review of Molecular and Clinical Data</title><title>Explore (New York, N.Y.)</title><addtitle>Explore (NY)</addtitle><description>Zeel comp. N (Zeel) is a homeopathic medication that has been widely used for many years for the treatment of arthritic disorders in a large number of countries worldwide. In recent years, a growing body of clinical and molecular evidence has been accumulating that shed light on the possible antiarthritic effects of this preparation. A number of studies report anti-inflammatory effects from Zeel. In vitro studies have indicated Zeel-mediated inhibition of the pathways involving the enzymes cyclooxygenase-1 and -2, and also the 5-lipoxygenase pathways, affecting levels of both eicosanoids and leukotrienes. Thus, Zeel may reduce the main two classes of molecules responsible for arthritic pain and inflammation. This review describes recent research on Zeel and discusses the need for further studies to clarify the role of the compound in the antiarthritic armamentarium of complementary medicine.</description><subject>Anti-Inflammatory Agents, Non-Steroidal - pharmacology</subject><subject>Anti-Inflammatory Agents, Non-Steroidal - therapeutic use</subject><subject>Arthritis</subject><subject>Arthritis - drug therapy</subject><subject>cyclooxygenases</subject><subject>Dose-Response Relationship, Drug</subject><subject>Evidence-Based Medicine</subject><subject>homeopathy</subject><subject>Homeopathy - methods</subject><subject>Humans</subject><subject>leukotrienes</subject><subject>Meta-Analysis as Topic</subject><subject>Plant Extracts - pharmacology</subject><subject>Plant Extracts - therapeutic use</subject><subject>prostaglandins</subject><subject>Randomized Controlled Trials as Topic</subject><subject>Sulfur Compounds</subject><issn>1550-8307</issn><issn>1878-7541</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2007</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkE1v1DAQhi0EoqXwE0A-cUsY24md5YJWS6FIpSBULhywZp2J6pUTBztLy7_Hq12JI4fRfOideTUPYy8F1AKEfrOr6WEOMVEtAXSZ1QDyETsXnekq0zbicanbFqpOgTljz3LeASjdav2UnQkjVdPq5pz9vL0jfhVHijMud97x9bR4TKVcSvM10YwJFx8n_oMocBfHueY3b_maf6Pfnu55HPjnGMjtAyaOU883wU_eYeDvccHn7MmAIdOLU75g3z9c3m6uqusvHz9t1teVU1otlRG6F4Mg2G6hb5rVSmjVEwrVa92CGRpHqkNJUjTGAKmtROwEojQgByUadcFeH-_OKf7aU17s6LOjEHCiuM9WdytZAoqwPQpdijknGuyc_IjpjxVgD2Dtzp7A2gPYw7iALXuvTgb77Uj9v60TySJ4dxRQebOQSTY7T5Oj3idyi-2j_4_FX6ofi2I</recordid><startdate>2007</startdate><enddate>2007</enddate><creator>Birnesser, Heinz</creator><creator>Stolt, Pelle</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>2007</creationdate><title>The Homeopathic Antiarthitic Preparation Zeel comp. N: A Review of Molecular and Clinical Data</title><author>Birnesser, Heinz ; Stolt, Pelle</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c363t-716d1f1e0bb0d4499163dea13d66507f4ce38a2e214770e3b2aa81aa2702f3143</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2007</creationdate><topic>Anti-Inflammatory Agents, Non-Steroidal - pharmacology</topic><topic>Anti-Inflammatory Agents, Non-Steroidal - therapeutic use</topic><topic>Arthritis</topic><topic>Arthritis - drug therapy</topic><topic>cyclooxygenases</topic><topic>Dose-Response Relationship, Drug</topic><topic>Evidence-Based Medicine</topic><topic>homeopathy</topic><topic>Homeopathy - methods</topic><topic>Humans</topic><topic>leukotrienes</topic><topic>Meta-Analysis as Topic</topic><topic>Plant Extracts - pharmacology</topic><topic>Plant Extracts - therapeutic use</topic><topic>prostaglandins</topic><topic>Randomized Controlled Trials as Topic</topic><topic>Sulfur Compounds</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Birnesser, Heinz</creatorcontrib><creatorcontrib>Stolt, Pelle</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Explore (New York, N.Y.)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Birnesser, Heinz</au><au>Stolt, Pelle</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The Homeopathic Antiarthitic Preparation Zeel comp. N: A Review of Molecular and Clinical Data</atitle><jtitle>Explore (New York, N.Y.)</jtitle><addtitle>Explore (NY)</addtitle><date>2007</date><risdate>2007</risdate><volume>3</volume><issue>1</issue><spage>16</spage><epage>22</epage><pages>16-22</pages><issn>1550-8307</issn><eissn>1878-7541</eissn><abstract>Zeel comp. N (Zeel) is a homeopathic medication that has been widely used for many years for the treatment of arthritic disorders in a large number of countries worldwide. In recent years, a growing body of clinical and molecular evidence has been accumulating that shed light on the possible antiarthritic effects of this preparation. A number of studies report anti-inflammatory effects from Zeel. In vitro studies have indicated Zeel-mediated inhibition of the pathways involving the enzymes cyclooxygenase-1 and -2, and also the 5-lipoxygenase pathways, affecting levels of both eicosanoids and leukotrienes. Thus, Zeel may reduce the main two classes of molecules responsible for arthritic pain and inflammation. This review describes recent research on Zeel and discusses the need for further studies to clarify the role of the compound in the antiarthritic armamentarium of complementary medicine.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>17234564</pmid><doi>10.1016/j.explore.2006.10.002</doi><tpages>7</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1550-8307 |
| ispartof | Explore (New York, N.Y.), 2007, Vol.3 (1), p.16-22 |
| issn | 1550-8307 1878-7541 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_68926890 |
| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Anti-Inflammatory Agents, Non-Steroidal - pharmacology Anti-Inflammatory Agents, Non-Steroidal - therapeutic use Arthritis Arthritis - drug therapy cyclooxygenases Dose-Response Relationship, Drug Evidence-Based Medicine homeopathy Homeopathy - methods Humans leukotrienes Meta-Analysis as Topic Plant Extracts - pharmacology Plant Extracts - therapeutic use prostaglandins Randomized Controlled Trials as Topic Sulfur Compounds |
| title | The Homeopathic Antiarthitic Preparation Zeel comp. N: A Review of Molecular and Clinical Data |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-12T09%3A38%3A21IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=The%20Homeopathic%20Antiarthitic%20Preparation%20Zeel%20comp.%20N:%20A%20Review%20of%20Molecular%20and%20Clinical%20Data&rft.jtitle=Explore%20(New%20York,%20N.Y.)&rft.au=Birnesser,%20Heinz&rft.date=2007&rft.volume=3&rft.issue=1&rft.spage=16&rft.epage=22&rft.pages=16-22&rft.issn=1550-8307&rft.eissn=1878-7541&rft_id=info:doi/10.1016/j.explore.2006.10.002&rft_dat=%3Cproquest_cross%3E68926890%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=68926890&rft_id=info:pmid/17234564&rft_els_id=S1550830706004526&rfr_iscdi=true |