Death of a trypanosome: a selfish altruism
African trypanosomes and some related parasitic protozoa are affected by a form of programmed cell death (PCD) that shows typical hallmarks of apoptosis. Although it has been speculated that PCD has a function in life-cycle progression and the struggle for survival of these parasites, no satisfactor...
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| Veröffentlicht in: | Trends in parasitology 2006-11, Vol.22 (11), p.536-542 |
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| creator | Duszenko, Michael Figarella, Katherine Macleod, Ewan T. Welburn, Susan C. |
| description | African trypanosomes and some related parasitic protozoa are affected by a form of programmed cell death (PCD) that shows typical hallmarks of apoptosis. Although it has been speculated that PCD has a function in life-cycle progression and the struggle for survival of these parasites, no satisfactory model has yet been proposed for the molecular mechanism(s) of PCD in protozoa, raising questions about its physiological relevance in these organisms. As we discuss here, the most important point that needs to be addressed is whether a single-celled organism can undertake a process that is considered altruistic. |
| doi_str_mv | 10.1016/j.pt.2006.08.010 |
| format | Article |
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| ispartof | Trends in parasitology, 2006-11, Vol.22 (11), p.536-542 |
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| language | eng |
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| source | MEDLINE; Elsevier ScienceDirect Journals Complete |
| subjects | Animals Apoptosis Biological and medical sciences Fundamental and applied biological sciences. Psychology General aspects and techniques Host-Parasite Interactions Protozoa Trypanosoma Trypanosoma - parasitology Trypanosoma - physiology |
| title | Death of a trypanosome: a selfish altruism |
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