Functional MR study of a motor task and the Tower of london task at 1.0 T
The use of functional magnetic resonance imaging (fMRI) for clinical applications and basic neuroscience is constantly increasing. The discussion about minimum performance requirement for a correct implementation of fMRI is still open, and one of the critical points is the magnetic field strength. W...
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| Veröffentlicht in: | Neuroradiology 2006-10, Vol.48 (10), p.763-771 |
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| creator | BOGHI, A RAMPADO, O BERGUI, M AVIDANO, F MANZONE, C CORIASCO, M MORTARA, P ORSI, L ROPOLO, R BRADAC, G. B |
| description | The use of functional magnetic resonance imaging (fMRI) for clinical applications and basic neuroscience is constantly increasing. The discussion about minimum performance requirement for a correct implementation of fMRI is still open, and one of the critical points is the magnetic field strength. We tested the feasibility of fMRI at 1.0 T during motor and cognitive tasks.
Fourteen healthy subjects were scanned during a motor task and 12 while performing the Tower of London task. In the activated areas, the percentage signal change due to BOLD (blood oxygenation level dependent) contrast was analysed. To check basic image quality of the acquisition system we measured quality indices in a temporal series of images of a phantom.
Motor and cognitive brain activations matched previous results obtained at higher field strengths. The mean percentage change over subjects in the motor task was in the range 1.3-2.6% for the primary motor area and 0.8-6.7% for the cerebellum. In the cognitive task, the mean percentage change over subjects was 0.7-1.2% for a frontal area and 0.6-2.8% for a parietal area. The percentage noise of the phantom temporal series was less than 0.4%. Percentage changes and signal to noise ratio, although lower than that obtained with high-field systems, allowed activation maps to be obtained in all subjects.
Our results replicate previous fMRI results demonstrating reproducible motor-related brain activations and extend the field to a complex cognitive task, thus providing evidence of the safety for routine clinical use of 1-T equipment. |
| doi_str_mv | 10.1007/s00234-006-0119-7 |
| format | Article |
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Fourteen healthy subjects were scanned during a motor task and 12 while performing the Tower of London task. In the activated areas, the percentage signal change due to BOLD (blood oxygenation level dependent) contrast was analysed. To check basic image quality of the acquisition system we measured quality indices in a temporal series of images of a phantom.
Motor and cognitive brain activations matched previous results obtained at higher field strengths. The mean percentage change over subjects in the motor task was in the range 1.3-2.6% for the primary motor area and 0.8-6.7% for the cerebellum. In the cognitive task, the mean percentage change over subjects was 0.7-1.2% for a frontal area and 0.6-2.8% for a parietal area. The percentage noise of the phantom temporal series was less than 0.4%. Percentage changes and signal to noise ratio, although lower than that obtained with high-field systems, allowed activation maps to be obtained in all subjects.
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Fourteen healthy subjects were scanned during a motor task and 12 while performing the Tower of London task. In the activated areas, the percentage signal change due to BOLD (blood oxygenation level dependent) contrast was analysed. To check basic image quality of the acquisition system we measured quality indices in a temporal series of images of a phantom.
Motor and cognitive brain activations matched previous results obtained at higher field strengths. The mean percentage change over subjects in the motor task was in the range 1.3-2.6% for the primary motor area and 0.8-6.7% for the cerebellum. In the cognitive task, the mean percentage change over subjects was 0.7-1.2% for a frontal area and 0.6-2.8% for a parietal area. The percentage noise of the phantom temporal series was less than 0.4%. Percentage changes and signal to noise ratio, although lower than that obtained with high-field systems, allowed activation maps to be obtained in all subjects.
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B</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Functional MR study of a motor task and the Tower of london task at 1.0 T</atitle><jtitle>Neuroradiology</jtitle><addtitle>Neuroradiology</addtitle><date>2006-10-01</date><risdate>2006</risdate><volume>48</volume><issue>10</issue><spage>763</spage><epage>771</epage><pages>763-771</pages><issn>0028-3940</issn><eissn>1432-1920</eissn><coden>NRDYAB</coden><abstract>The use of functional magnetic resonance imaging (fMRI) for clinical applications and basic neuroscience is constantly increasing. The discussion about minimum performance requirement for a correct implementation of fMRI is still open, and one of the critical points is the magnetic field strength. We tested the feasibility of fMRI at 1.0 T during motor and cognitive tasks.
Fourteen healthy subjects were scanned during a motor task and 12 while performing the Tower of London task. In the activated areas, the percentage signal change due to BOLD (blood oxygenation level dependent) contrast was analysed. To check basic image quality of the acquisition system we measured quality indices in a temporal series of images of a phantom.
Motor and cognitive brain activations matched previous results obtained at higher field strengths. The mean percentage change over subjects in the motor task was in the range 1.3-2.6% for the primary motor area and 0.8-6.7% for the cerebellum. In the cognitive task, the mean percentage change over subjects was 0.7-1.2% for a frontal area and 0.6-2.8% for a parietal area. The percentage noise of the phantom temporal series was less than 0.4%. Percentage changes and signal to noise ratio, although lower than that obtained with high-field systems, allowed activation maps to be obtained in all subjects.
Our results replicate previous fMRI results demonstrating reproducible motor-related brain activations and extend the field to a complex cognitive task, thus providing evidence of the safety for routine clinical use of 1-T equipment.</abstract><cop>Berlin</cop><pub>Springer</pub><pmid>16944122</pmid><doi>10.1007/s00234-006-0119-7</doi><tpages>9</tpages></addata></record> |
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| subjects | Adult Biological and medical sciences Brain - physiology Cognition - physiology Electrodiagnosis. Electric activity recording Equipment testing Feasibility Studies Female Fundamental and applied biological sciences. Psychology Human Humans Image Processing, Computer-Assisted Investigative techniques, diagnostic techniques (general aspects) Learning. Memory Magnetic fields Magnetic Resonance Imaging Male Medical sciences Memory Motor ability Motor Activity - physiology Nervous system NMR Nuclear magnetic resonance Psychology. Psychoanalysis. Psychiatry Psychology. Psychophysiology Quality control Radiodiagnosis. Nmr imagery. Nmr spectrometry Reference Values Task Performance and Analysis |
| title | Functional MR study of a motor task and the Tower of london task at 1.0 T |
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