Diagnosed Tuberculosis During the Follow-up of a Cohort of Human Immunodeficiency Virus-Infected Children in Abidjan, Côte dʼIvoire: ANRS 1278 Study
INTRODUCTION:Most data on tuberculosis in human immunodeficiency virus (HIV)-infected children in Africa come from hospital-based and cross-sectional studies. OBJECTIVES:To estimate the incidence of tuberculosis in HIV-infected children participating in an observational cohort. METHODS:HIV-infected...
Gespeichert in:
| Veröffentlicht in: | The Pediatric infectious disease journal 2005-12, Vol.24 (12), p.1077-1082 |
|---|---|
| Hauptverfasser: | , , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 1082 |
|---|---|
| container_issue | 12 |
| container_start_page | 1077 |
| container_title | The Pediatric infectious disease journal |
| container_volume | 24 |
| creator | Elenga, Narcisse Kouakoussui, Kouakou Alain Bonard, Dominique Fassinou, Patricia Anaky, Marie-France Wemin, Marie-Louise Dick-Amon-Tanoh, Flore Rouet, François Vincent, Véronique Msellati, Philippe |
| description | INTRODUCTION:Most data on tuberculosis in human immunodeficiency virus (HIV)-infected children in Africa come from hospital-based and cross-sectional studies.
OBJECTIVES:To estimate the incidence of tuberculosis in HIV-infected children participating in an observational cohort.
METHODS:HIV-infected children in Abidjan, Côte dʼIvoire, are followed in a prospective cohort. At enrollment, all children had a physical examination, CD4 lymphocyte counts, chest radiograph and a tuberculin test. Quarterly follow-up visits are organized. All patients with suspected tuberculosis undergo specific investigations including gastric aspiration and culture. All isolates are tested for susceptibility.
RESULTS:From October 2000 to December 2003, 129 girls and 153 boys were recruited. Of children without a current or previous diagnosis of tuberculosis, 6.5% (13 of 199) had a tuberculin test result of >5 mm, compared with 17.5% of children (10 of 57) with current or previous tuberculosis (P < 0.02). Forty-eight children (17%) had a history of treated tuberculosis, and 27 children were being treated for tuberculosis at enrollment or during the first month of follow-up. Eleven children were diagnosed with tuberculosis after the first month of follow-up, and the diagnosis of mycobacterial infection was confirmed in 7 cases. Of 5 tested isolates of Mycobacterium tuberculosis, 3 were resistant to at least 1 antitubercular drug.Cumulative incidence of tuberculosis was 2060/100,000 at 12 months, 3390/100,000 at 2 years and 5930/100,000 at 3 years. The 3-year risk was 12,400/100,000 in immunocompromised children (CD4 |
| doi_str_mv | 10.1097/01.inf.0000190008.91534.b7 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_proquest_miscellaneous_68914450</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>68914450</sourcerecordid><originalsourceid>FETCH-LOGICAL-p2841-2484a479096279311afa264056f6a0313b9a76150abe40033ff7e66978b5fe793</originalsourceid><addsrcrecordid>eNpFkcFu1DAQhi0EokvhFZCFBCcS7NixY26rlNKVKpBo4Ro5id24OPbWjlnti_AkHLlx46nw0kXM4Z85fDPS_D8ALzAqMRL8DcKlcbpEubDI0pQC14SWPX8AVnmqCiQa_hCsUCNwQRhrTsCTGG8zSihGj8EJZoTjhokV-H5m5I3zUY3wOvUqDMn6aCI8S8G4G7hMCp57a_2uSFvoNZSw9ZMPy2G-SLN0cDPPyflRaTMY5YY9_GJCisXGaTUs-Ww7GTsG5aBxcN2b8Va617D99WNRcPz9c_PNm6DewvWHT1cQV7yBV0sa90_BIy1tVM-O_RR8Pn933V4Ulx_fb9r1ZbGtGoqLijZUUi6QYBUXBGOpZcUoqplmEhFMeiE5wzWSvaL5e6I1V4wJ3vS1VnnjFLy6v7sN_i6puHSziYOyVjrlU-xYdpDSGmXw-RFM_azGbhvMLMO---dkBl4eARkHaXWQbjDxP8dJ3dR_OXrP7bxdVIhfbdqp0E1K2mXqDpkyWtOiQqjGWVBxSBmTP8mXlK0</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>68914450</pqid></control><display><type>article</type><title>Diagnosed Tuberculosis During the Follow-up of a Cohort of Human Immunodeficiency Virus-Infected Children in Abidjan, Côte dʼIvoire: ANRS 1278 Study</title><source>MEDLINE</source><source>Journals@Ovid Complete</source><creator>Elenga, Narcisse ; Kouakoussui, Kouakou Alain ; Bonard, Dominique ; Fassinou, Patricia ; Anaky, Marie-France ; Wemin, Marie-Louise ; Dick-Amon-Tanoh, Flore ; Rouet, François ; Vincent, Véronique ; Msellati, Philippe</creator><creatorcontrib>Elenga, Narcisse ; Kouakoussui, Kouakou Alain ; Bonard, Dominique ; Fassinou, Patricia ; Anaky, Marie-France ; Wemin, Marie-Louise ; Dick-Amon-Tanoh, Flore ; Rouet, François ; Vincent, Véronique ; Msellati, Philippe</creatorcontrib><description>INTRODUCTION:Most data on tuberculosis in human immunodeficiency virus (HIV)-infected children in Africa come from hospital-based and cross-sectional studies.
OBJECTIVES:To estimate the incidence of tuberculosis in HIV-infected children participating in an observational cohort.
METHODS:HIV-infected children in Abidjan, Côte dʼIvoire, are followed in a prospective cohort. At enrollment, all children had a physical examination, CD4 lymphocyte counts, chest radiograph and a tuberculin test. Quarterly follow-up visits are organized. All patients with suspected tuberculosis undergo specific investigations including gastric aspiration and culture. All isolates are tested for susceptibility.
RESULTS:From October 2000 to December 2003, 129 girls and 153 boys were recruited. Of children without a current or previous diagnosis of tuberculosis, 6.5% (13 of 199) had a tuberculin test result of >5 mm, compared with 17.5% of children (10 of 57) with current or previous tuberculosis (P < 0.02). Forty-eight children (17%) had a history of treated tuberculosis, and 27 children were being treated for tuberculosis at enrollment or during the first month of follow-up. Eleven children were diagnosed with tuberculosis after the first month of follow-up, and the diagnosis of mycobacterial infection was confirmed in 7 cases. Of 5 tested isolates of Mycobacterium tuberculosis, 3 were resistant to at least 1 antitubercular drug.Cumulative incidence of tuberculosis was 2060/100,000 at 12 months, 3390/100,000 at 2 years and 5930/100,000 at 3 years. The 3-year risk was 12,400/100,000 in immunocompromised children (CD4 <15%) and 3300/100,000 in other children (P < 0.0001).
CONCLUSION:The risk of tuberculosis among HIV-infected children in Côte dʼIvoire is strongly associated with the degree of immunodeficiency in HIV infection.</description><identifier>ISSN: 0891-3668</identifier><identifier>EISSN: 1532-0987</identifier><identifier>DOI: 10.1097/01.inf.0000190008.91534.b7</identifier><identifier>PMID: 16371869</identifier><identifier>CODEN: PIDJEV</identifier><language>eng</language><publisher>Baltimore, MD: Lippincott Williams & Wilkins, Inc</publisher><subject>Adolescent ; AIDS-Related Opportunistic Infections - diagnosis ; AIDS-Related Opportunistic Infections - epidemiology ; AIDS-Related Opportunistic Infections - microbiology ; Bacterial diseases ; Biological and medical sciences ; CD4 Lymphocyte Count ; Child ; Child, Preschool ; Cohort Studies ; Cote d'Ivoire - epidemiology ; Female ; HIV Infections - complications ; Human bacterial diseases ; Human viral diseases ; Humans ; Immunodeficiencies ; Immunodeficiencies. Immunoglobulinopathies ; Immunopathology ; Incidence ; Infant ; Infectious diseases ; Male ; Medical sciences ; Mycobacterium tuberculosis - isolation & purification ; Prospective Studies ; Tuberculin Test ; Tuberculosis - diagnosis ; Tuberculosis - epidemiology ; Tuberculosis - microbiology ; Tuberculosis and atypical mycobacterial infections ; Viral diseases ; Viral diseases of the lymphoid tissue and the blood. Aids</subject><ispartof>The Pediatric infectious disease journal, 2005-12, Vol.24 (12), p.1077-1082</ispartof><rights>2005 Lippincott Williams & Wilkins, Inc.</rights><rights>2006 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>315,781,785,27926,27927</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=17358569$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/16371869$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Elenga, Narcisse</creatorcontrib><creatorcontrib>Kouakoussui, Kouakou Alain</creatorcontrib><creatorcontrib>Bonard, Dominique</creatorcontrib><creatorcontrib>Fassinou, Patricia</creatorcontrib><creatorcontrib>Anaky, Marie-France</creatorcontrib><creatorcontrib>Wemin, Marie-Louise</creatorcontrib><creatorcontrib>Dick-Amon-Tanoh, Flore</creatorcontrib><creatorcontrib>Rouet, François</creatorcontrib><creatorcontrib>Vincent, Véronique</creatorcontrib><creatorcontrib>Msellati, Philippe</creatorcontrib><title>Diagnosed Tuberculosis During the Follow-up of a Cohort of Human Immunodeficiency Virus-Infected Children in Abidjan, Côte dʼIvoire: ANRS 1278 Study</title><title>The Pediatric infectious disease journal</title><addtitle>Pediatr Infect Dis J</addtitle><description>INTRODUCTION:Most data on tuberculosis in human immunodeficiency virus (HIV)-infected children in Africa come from hospital-based and cross-sectional studies.
OBJECTIVES:To estimate the incidence of tuberculosis in HIV-infected children participating in an observational cohort.
METHODS:HIV-infected children in Abidjan, Côte dʼIvoire, are followed in a prospective cohort. At enrollment, all children had a physical examination, CD4 lymphocyte counts, chest radiograph and a tuberculin test. Quarterly follow-up visits are organized. All patients with suspected tuberculosis undergo specific investigations including gastric aspiration and culture. All isolates are tested for susceptibility.
RESULTS:From October 2000 to December 2003, 129 girls and 153 boys were recruited. Of children without a current or previous diagnosis of tuberculosis, 6.5% (13 of 199) had a tuberculin test result of >5 mm, compared with 17.5% of children (10 of 57) with current or previous tuberculosis (P < 0.02). Forty-eight children (17%) had a history of treated tuberculosis, and 27 children were being treated for tuberculosis at enrollment or during the first month of follow-up. Eleven children were diagnosed with tuberculosis after the first month of follow-up, and the diagnosis of mycobacterial infection was confirmed in 7 cases. Of 5 tested isolates of Mycobacterium tuberculosis, 3 were resistant to at least 1 antitubercular drug.Cumulative incidence of tuberculosis was 2060/100,000 at 12 months, 3390/100,000 at 2 years and 5930/100,000 at 3 years. The 3-year risk was 12,400/100,000 in immunocompromised children (CD4 <15%) and 3300/100,000 in other children (P < 0.0001).
CONCLUSION:The risk of tuberculosis among HIV-infected children in Côte dʼIvoire is strongly associated with the degree of immunodeficiency in HIV infection.</description><subject>Adolescent</subject><subject>AIDS-Related Opportunistic Infections - diagnosis</subject><subject>AIDS-Related Opportunistic Infections - epidemiology</subject><subject>AIDS-Related Opportunistic Infections - microbiology</subject><subject>Bacterial diseases</subject><subject>Biological and medical sciences</subject><subject>CD4 Lymphocyte Count</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>Cohort Studies</subject><subject>Cote d'Ivoire - epidemiology</subject><subject>Female</subject><subject>HIV Infections - complications</subject><subject>Human bacterial diseases</subject><subject>Human viral diseases</subject><subject>Humans</subject><subject>Immunodeficiencies</subject><subject>Immunodeficiencies. Immunoglobulinopathies</subject><subject>Immunopathology</subject><subject>Incidence</subject><subject>Infant</subject><subject>Infectious diseases</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Mycobacterium tuberculosis - isolation & purification</subject><subject>Prospective Studies</subject><subject>Tuberculin Test</subject><subject>Tuberculosis - diagnosis</subject><subject>Tuberculosis - epidemiology</subject><subject>Tuberculosis - microbiology</subject><subject>Tuberculosis and atypical mycobacterial infections</subject><subject>Viral diseases</subject><subject>Viral diseases of the lymphoid tissue and the blood. Aids</subject><issn>0891-3668</issn><issn>1532-0987</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2005</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFkcFu1DAQhi0EokvhFZCFBCcS7NixY26rlNKVKpBo4Ro5id24OPbWjlnti_AkHLlx46nw0kXM4Z85fDPS_D8ALzAqMRL8DcKlcbpEubDI0pQC14SWPX8AVnmqCiQa_hCsUCNwQRhrTsCTGG8zSihGj8EJZoTjhokV-H5m5I3zUY3wOvUqDMn6aCI8S8G4G7hMCp57a_2uSFvoNZSw9ZMPy2G-SLN0cDPPyflRaTMY5YY9_GJCisXGaTUs-Ww7GTsG5aBxcN2b8Va617D99WNRcPz9c_PNm6DewvWHT1cQV7yBV0sa90_BIy1tVM-O_RR8Pn933V4Ulx_fb9r1ZbGtGoqLijZUUi6QYBUXBGOpZcUoqplmEhFMeiE5wzWSvaL5e6I1V4wJ3vS1VnnjFLy6v7sN_i6puHSziYOyVjrlU-xYdpDSGmXw-RFM_azGbhvMLMO---dkBl4eARkHaXWQbjDxP8dJ3dR_OXrP7bxdVIhfbdqp0E1K2mXqDpkyWtOiQqjGWVBxSBmTP8mXlK0</recordid><startdate>200512</startdate><enddate>200512</enddate><creator>Elenga, Narcisse</creator><creator>Kouakoussui, Kouakou Alain</creator><creator>Bonard, Dominique</creator><creator>Fassinou, Patricia</creator><creator>Anaky, Marie-France</creator><creator>Wemin, Marie-Louise</creator><creator>Dick-Amon-Tanoh, Flore</creator><creator>Rouet, François</creator><creator>Vincent, Véronique</creator><creator>Msellati, Philippe</creator><general>Lippincott Williams & Wilkins, Inc</general><general>Lippincott</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>200512</creationdate><title>Diagnosed Tuberculosis During the Follow-up of a Cohort of Human Immunodeficiency Virus-Infected Children in Abidjan, Côte dʼIvoire: ANRS 1278 Study</title><author>Elenga, Narcisse ; Kouakoussui, Kouakou Alain ; Bonard, Dominique ; Fassinou, Patricia ; Anaky, Marie-France ; Wemin, Marie-Louise ; Dick-Amon-Tanoh, Flore ; Rouet, François ; Vincent, Véronique ; Msellati, Philippe</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p2841-2484a479096279311afa264056f6a0313b9a76150abe40033ff7e66978b5fe793</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2005</creationdate><topic>Adolescent</topic><topic>AIDS-Related Opportunistic Infections - diagnosis</topic><topic>AIDS-Related Opportunistic Infections - epidemiology</topic><topic>AIDS-Related Opportunistic Infections - microbiology</topic><topic>Bacterial diseases</topic><topic>Biological and medical sciences</topic><topic>CD4 Lymphocyte Count</topic><topic>Child</topic><topic>Child, Preschool</topic><topic>Cohort Studies</topic><topic>Cote d'Ivoire - epidemiology</topic><topic>Female</topic><topic>HIV Infections - complications</topic><topic>Human bacterial diseases</topic><topic>Human viral diseases</topic><topic>Humans</topic><topic>Immunodeficiencies</topic><topic>Immunodeficiencies. Immunoglobulinopathies</topic><topic>Immunopathology</topic><topic>Incidence</topic><topic>Infant</topic><topic>Infectious diseases</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Mycobacterium tuberculosis - isolation & purification</topic><topic>Prospective Studies</topic><topic>Tuberculin Test</topic><topic>Tuberculosis - diagnosis</topic><topic>Tuberculosis - epidemiology</topic><topic>Tuberculosis - microbiology</topic><topic>Tuberculosis and atypical mycobacterial infections</topic><topic>Viral diseases</topic><topic>Viral diseases of the lymphoid tissue and the blood. Aids</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Elenga, Narcisse</creatorcontrib><creatorcontrib>Kouakoussui, Kouakou Alain</creatorcontrib><creatorcontrib>Bonard, Dominique</creatorcontrib><creatorcontrib>Fassinou, Patricia</creatorcontrib><creatorcontrib>Anaky, Marie-France</creatorcontrib><creatorcontrib>Wemin, Marie-Louise</creatorcontrib><creatorcontrib>Dick-Amon-Tanoh, Flore</creatorcontrib><creatorcontrib>Rouet, François</creatorcontrib><creatorcontrib>Vincent, Véronique</creatorcontrib><creatorcontrib>Msellati, Philippe</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>The Pediatric infectious disease journal</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Elenga, Narcisse</au><au>Kouakoussui, Kouakou Alain</au><au>Bonard, Dominique</au><au>Fassinou, Patricia</au><au>Anaky, Marie-France</au><au>Wemin, Marie-Louise</au><au>Dick-Amon-Tanoh, Flore</au><au>Rouet, François</au><au>Vincent, Véronique</au><au>Msellati, Philippe</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Diagnosed Tuberculosis During the Follow-up of a Cohort of Human Immunodeficiency Virus-Infected Children in Abidjan, Côte dʼIvoire: ANRS 1278 Study</atitle><jtitle>The Pediatric infectious disease journal</jtitle><addtitle>Pediatr Infect Dis J</addtitle><date>2005-12</date><risdate>2005</risdate><volume>24</volume><issue>12</issue><spage>1077</spage><epage>1082</epage><pages>1077-1082</pages><issn>0891-3668</issn><eissn>1532-0987</eissn><coden>PIDJEV</coden><abstract>INTRODUCTION:Most data on tuberculosis in human immunodeficiency virus (HIV)-infected children in Africa come from hospital-based and cross-sectional studies.
OBJECTIVES:To estimate the incidence of tuberculosis in HIV-infected children participating in an observational cohort.
METHODS:HIV-infected children in Abidjan, Côte dʼIvoire, are followed in a prospective cohort. At enrollment, all children had a physical examination, CD4 lymphocyte counts, chest radiograph and a tuberculin test. Quarterly follow-up visits are organized. All patients with suspected tuberculosis undergo specific investigations including gastric aspiration and culture. All isolates are tested for susceptibility.
RESULTS:From October 2000 to December 2003, 129 girls and 153 boys were recruited. Of children without a current or previous diagnosis of tuberculosis, 6.5% (13 of 199) had a tuberculin test result of >5 mm, compared with 17.5% of children (10 of 57) with current or previous tuberculosis (P < 0.02). Forty-eight children (17%) had a history of treated tuberculosis, and 27 children were being treated for tuberculosis at enrollment or during the first month of follow-up. Eleven children were diagnosed with tuberculosis after the first month of follow-up, and the diagnosis of mycobacterial infection was confirmed in 7 cases. Of 5 tested isolates of Mycobacterium tuberculosis, 3 were resistant to at least 1 antitubercular drug.Cumulative incidence of tuberculosis was 2060/100,000 at 12 months, 3390/100,000 at 2 years and 5930/100,000 at 3 years. The 3-year risk was 12,400/100,000 in immunocompromised children (CD4 <15%) and 3300/100,000 in other children (P < 0.0001).
CONCLUSION:The risk of tuberculosis among HIV-infected children in Côte dʼIvoire is strongly associated with the degree of immunodeficiency in HIV infection.</abstract><cop>Baltimore, MD</cop><cop>Philadelphia, PA</cop><cop>Hagerstown, MD</cop><pub>Lippincott Williams & Wilkins, Inc</pub><pmid>16371869</pmid><doi>10.1097/01.inf.0000190008.91534.b7</doi><tpages>6</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0891-3668 |
| ispartof | The Pediatric infectious disease journal, 2005-12, Vol.24 (12), p.1077-1082 |
| issn | 0891-3668 1532-0987 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_68914450 |
| source | MEDLINE; Journals@Ovid Complete |
| subjects | Adolescent AIDS-Related Opportunistic Infections - diagnosis AIDS-Related Opportunistic Infections - epidemiology AIDS-Related Opportunistic Infections - microbiology Bacterial diseases Biological and medical sciences CD4 Lymphocyte Count Child Child, Preschool Cohort Studies Cote d'Ivoire - epidemiology Female HIV Infections - complications Human bacterial diseases Human viral diseases Humans Immunodeficiencies Immunodeficiencies. Immunoglobulinopathies Immunopathology Incidence Infant Infectious diseases Male Medical sciences Mycobacterium tuberculosis - isolation & purification Prospective Studies Tuberculin Test Tuberculosis - diagnosis Tuberculosis - epidemiology Tuberculosis - microbiology Tuberculosis and atypical mycobacterial infections Viral diseases Viral diseases of the lymphoid tissue and the blood. Aids |
| title | Diagnosed Tuberculosis During the Follow-up of a Cohort of Human Immunodeficiency Virus-Infected Children in Abidjan, Côte dʼIvoire: ANRS 1278 Study |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-18T11%3A06%3A52IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Diagnosed%20Tuberculosis%20During%20the%20Follow-up%20of%20a%20Cohort%20of%20Human%20Immunodeficiency%20Virus-Infected%20Children%20in%20Abidjan,%20C%C3%B4te%20d%CA%BCIvoire:%20ANRS%201278%20Study&rft.jtitle=The%20Pediatric%20infectious%20disease%20journal&rft.au=Elenga,%20Narcisse&rft.date=2005-12&rft.volume=24&rft.issue=12&rft.spage=1077&rft.epage=1082&rft.pages=1077-1082&rft.issn=0891-3668&rft.eissn=1532-0987&rft.coden=PIDJEV&rft_id=info:doi/10.1097/01.inf.0000190008.91534.b7&rft_dat=%3Cproquest_pubme%3E68914450%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=68914450&rft_id=info:pmid/16371869&rfr_iscdi=true |