“Indeterminate” Microvolt T-Wave Alternans Tests Predict High Risk of Death or Sustained Ventricular Arrhythmias in Patients With Left Ventricular Dysfunction
“Indeterminate” Microvolt T-Wave Alternans Tests Predict High Risk of Death or Sustained Ventricular Arrhythmias in Patients With Left Ventricular Dysfunction Elizabeth S. Kaufman, Daniel M. Bloomfield, Richard C. Steinman, Pearila B. Namerow, Ottorino Costantini, Richard J. Cohen, J. Thomas Bigger...
Gespeichert in:
| Veröffentlicht in: | Journal of the American College of Cardiology 2006-10, Vol.48 (7), p.1399-1404 |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 1404 |
|---|---|
| container_issue | 7 |
| container_start_page | 1399 |
| container_title | Journal of the American College of Cardiology |
| container_volume | 48 |
| creator | Kaufman, Elizabeth S. Bloomfield, Daniel M. Steinman, Richard C. Namerow, Pearila B. Costantini, Ottorino Cohen, Richard J. Bigger, J. Thomas |
| description | “Indeterminate” Microvolt T-Wave Alternans Tests Predict High Risk of Death or Sustained Ventricular Arrhythmias in Patients With Left Ventricular Dysfunction
Elizabeth S. Kaufman, Daniel M. Bloomfield, Richard C. Steinman, Pearila B. Namerow, Ottorino Costantini, Richard J. Cohen, J. Thomas Bigger Jr
We performed a microvolt T-wave alternans (MTWA) exercise test in 549 patients with left ventricular ejection fraction ≤0.40 and followed them for 2 years. Among MTWA tests classified as “indeterminate,” 94% were so classified owing to ventricular ectopy, unsustained MTWA, or low exercise heart rate. Patients with an indeterminate MTWA test were at least as likely to die or experience a non-fatal sustained ventricular arrhythmia (SVA) as those with a positive test. Therefore, patients with indeterminate and positive MTWA tests can be combined into a single “abnormal” group at high risk of death or SVAs.
This study tested the hypothesis that an “indeterminate” microvolt T-wave alternans (MTWA) test, when due to ectopy, unsustained MTWA, or low exercise heart rate (HR), has prognostic significance similar to a positive MTWA test.
MTWA testing, used to stratify risk of sudden or total mortality in patients with structural heart disease, has been limited by a substantial number of “indeterminate” tests. Indeterminate tests are due to patient factors—excessive ventricular ectopy during exercise, unsustained MTWA, or failure to achieve a HR of 105 beats/min for 1 min—or technical factors such as a noisy recording or an exercise protocol that causes an excessively rapid rise in HR.
Patients in sinus rhythm with left ventricular ejection fraction ≤0.40 underwent MTWA exercise tests, analyzed with the spectral method and classified by a computerized interpretation algorithm. The primary end point was all-cause mortality or documented non-fatal sustained ventricular arrhythmia (SVA). “Indeterminate” tests were reviewed jointly by 2 readers blinded to subsequent events to determine the primary reason for indeterminacy.
Participants (N = 549) were 56 ± 13 years and 71% male; 49% had ischemic cardiomyopathy. There were 40 deaths and 11 non-fatal SVA. Most (94%) indeterminate results were due to patient factors. The 2-year rate for death or SVA was 17.8% in patients with an “indeterminate” MTWA test compared with 12.3% in those with a positive test.
In patients with left ventricular dysfunction, an “indeterminate” MTWA test due to patient factors predicted death or SVA at |
| doi_str_mv | 10.1016/j.jacc.2006.06.044 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_68912304</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0735109706017943</els_id><sourcerecordid>68912304</sourcerecordid><originalsourceid>FETCH-LOGICAL-c447t-7efb75157b3fd33ea66cbcc8d311eb6a21c1a2ba755dc4812f437b3f6c34513a3</originalsourceid><addsrcrecordid>eNp9kcFu1DAQhi0EokvhBTggSwhuWezYThyJy6qltNIiKljo0XKcCeuQdVrbWWlvfZBy4dH6JDjalSo4II00h_nmH_v_EXpJyZwSWrzr5p02Zp4TUsyn4vwRmlEhZMZEVT5GM1IykVFSlUfoWQgdSaCk1VN0REtCiST5DP2-v727cA1E8BvrdIT721_4kzV-2A59xKvsSm8BL_o0d9oFvIIQA7700FgT8bn9scZfbPiJhxafgo5rPHj8dQxRWwcN_g4uemvGXnu88H69i-uN1QFbhy91tGka8JVNW0to41_06S60ozPRDu45etLqPsCLQz9G384-rE7Os-Xnjxcni2VmOC9jVkJbl4KKsmZtwxjoojC1MbJhlEJd6JwaqvNal0I0hkuat5xNbGEYF5Rpdoze7nWv_XAzpn-qjQ0G-l47GMagClnRnBGewNf_gN0wJnv6oKggBS2lYDJR-Z5KXobgoVXX3m603ylK1JSf6tSUn5ryU1PxSfrVQXqsN9A8rBwCS8CbA6CD0X3rtTM2PHCSFpJX0_X3ew6SY1sLXgWT_DYpNw8mqmaw_3vHH_3vvSM</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1506178538</pqid></control><display><type>article</type><title>“Indeterminate” Microvolt T-Wave Alternans Tests Predict High Risk of Death or Sustained Ventricular Arrhythmias in Patients With Left Ventricular Dysfunction</title><source>MEDLINE</source><source>Access via ScienceDirect (Elsevier)</source><source>EZB-FREE-00999 freely available EZB journals</source><source>Alma/SFX Local Collection</source><creator>Kaufman, Elizabeth S. ; Bloomfield, Daniel M. ; Steinman, Richard C. ; Namerow, Pearila B. ; Costantini, Ottorino ; Cohen, Richard J. ; Bigger, J. Thomas</creator><creatorcontrib>Kaufman, Elizabeth S. ; Bloomfield, Daniel M. ; Steinman, Richard C. ; Namerow, Pearila B. ; Costantini, Ottorino ; Cohen, Richard J. ; Bigger, J. Thomas</creatorcontrib><description>“Indeterminate” Microvolt T-Wave Alternans Tests Predict High Risk of Death or Sustained Ventricular Arrhythmias in Patients With Left Ventricular Dysfunction
Elizabeth S. Kaufman, Daniel M. Bloomfield, Richard C. Steinman, Pearila B. Namerow, Ottorino Costantini, Richard J. Cohen, J. Thomas Bigger Jr
We performed a microvolt T-wave alternans (MTWA) exercise test in 549 patients with left ventricular ejection fraction ≤0.40 and followed them for 2 years. Among MTWA tests classified as “indeterminate,” 94% were so classified owing to ventricular ectopy, unsustained MTWA, or low exercise heart rate. Patients with an indeterminate MTWA test were at least as likely to die or experience a non-fatal sustained ventricular arrhythmia (SVA) as those with a positive test. Therefore, patients with indeterminate and positive MTWA tests can be combined into a single “abnormal” group at high risk of death or SVAs.
This study tested the hypothesis that an “indeterminate” microvolt T-wave alternans (MTWA) test, when due to ectopy, unsustained MTWA, or low exercise heart rate (HR), has prognostic significance similar to a positive MTWA test.
MTWA testing, used to stratify risk of sudden or total mortality in patients with structural heart disease, has been limited by a substantial number of “indeterminate” tests. Indeterminate tests are due to patient factors—excessive ventricular ectopy during exercise, unsustained MTWA, or failure to achieve a HR of 105 beats/min for 1 min—or technical factors such as a noisy recording or an exercise protocol that causes an excessively rapid rise in HR.
Patients in sinus rhythm with left ventricular ejection fraction ≤0.40 underwent MTWA exercise tests, analyzed with the spectral method and classified by a computerized interpretation algorithm. The primary end point was all-cause mortality or documented non-fatal sustained ventricular arrhythmia (SVA). “Indeterminate” tests were reviewed jointly by 2 readers blinded to subsequent events to determine the primary reason for indeterminacy.
Participants (N = 549) were 56 ± 13 years and 71% male; 49% had ischemic cardiomyopathy. There were 40 deaths and 11 non-fatal SVA. Most (94%) indeterminate results were due to patient factors. The 2-year rate for death or SVA was 17.8% in patients with an “indeterminate” MTWA test compared with 12.3% in those with a positive test.
In patients with left ventricular dysfunction, an “indeterminate” MTWA test due to patient factors predicted death or SVA at least as well as a positive test.</description><identifier>ISSN: 0735-1097</identifier><identifier>EISSN: 1558-3597</identifier><identifier>DOI: 10.1016/j.jacc.2006.06.044</identifier><identifier>PMID: 17010802</identifier><identifier>CODEN: JACCDI</identifier><language>eng</language><publisher>New York, NY: Elsevier Inc</publisher><subject>Adult ; Aged ; Arrhythmias, Cardiac - etiology ; Biological and medical sciences ; Cardiac arrhythmia ; Cardiac dysrhythmias ; Cardiology ; Cardiology. Vascular system ; Electrophysiologic Techniques, Cardiac - methods ; Exercise Test ; Female ; Heart ; Heart attacks ; Heart failure, cardiogenic pulmonary edema, cardiac enlargement ; Heart Rate ; Humans ; Male ; Medical sciences ; Middle Aged ; Mortality ; Patients ; Predictive Value of Tests ; Prognosis ; Risk Assessment ; Ventricular Dysfunction, Left - complications ; Ventricular Dysfunction, Left - mortality</subject><ispartof>Journal of the American College of Cardiology, 2006-10, Vol.48 (7), p.1399-1404</ispartof><rights>2006 American College of Cardiology Foundation</rights><rights>2006 INIST-CNRS</rights><rights>Copyright Elsevier Limited Oct 3, 2006</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c447t-7efb75157b3fd33ea66cbcc8d311eb6a21c1a2ba755dc4812f437b3f6c34513a3</citedby><cites>FETCH-LOGICAL-c447t-7efb75157b3fd33ea66cbcc8d311eb6a21c1a2ba755dc4812f437b3f6c34513a3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.jacc.2006.06.044$$EHTML$$P50$$Gelsevier$$Hfree_for_read</linktohtml><link.rule.ids>315,782,786,3554,27933,27934,46004</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=18168498$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/17010802$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Kaufman, Elizabeth S.</creatorcontrib><creatorcontrib>Bloomfield, Daniel M.</creatorcontrib><creatorcontrib>Steinman, Richard C.</creatorcontrib><creatorcontrib>Namerow, Pearila B.</creatorcontrib><creatorcontrib>Costantini, Ottorino</creatorcontrib><creatorcontrib>Cohen, Richard J.</creatorcontrib><creatorcontrib>Bigger, J. Thomas</creatorcontrib><title>“Indeterminate” Microvolt T-Wave Alternans Tests Predict High Risk of Death or Sustained Ventricular Arrhythmias in Patients With Left Ventricular Dysfunction</title><title>Journal of the American College of Cardiology</title><addtitle>J Am Coll Cardiol</addtitle><description>“Indeterminate” Microvolt T-Wave Alternans Tests Predict High Risk of Death or Sustained Ventricular Arrhythmias in Patients With Left Ventricular Dysfunction
Elizabeth S. Kaufman, Daniel M. Bloomfield, Richard C. Steinman, Pearila B. Namerow, Ottorino Costantini, Richard J. Cohen, J. Thomas Bigger Jr
We performed a microvolt T-wave alternans (MTWA) exercise test in 549 patients with left ventricular ejection fraction ≤0.40 and followed them for 2 years. Among MTWA tests classified as “indeterminate,” 94% were so classified owing to ventricular ectopy, unsustained MTWA, or low exercise heart rate. Patients with an indeterminate MTWA test were at least as likely to die or experience a non-fatal sustained ventricular arrhythmia (SVA) as those with a positive test. Therefore, patients with indeterminate and positive MTWA tests can be combined into a single “abnormal” group at high risk of death or SVAs.
This study tested the hypothesis that an “indeterminate” microvolt T-wave alternans (MTWA) test, when due to ectopy, unsustained MTWA, or low exercise heart rate (HR), has prognostic significance similar to a positive MTWA test.
MTWA testing, used to stratify risk of sudden or total mortality in patients with structural heart disease, has been limited by a substantial number of “indeterminate” tests. Indeterminate tests are due to patient factors—excessive ventricular ectopy during exercise, unsustained MTWA, or failure to achieve a HR of 105 beats/min for 1 min—or technical factors such as a noisy recording or an exercise protocol that causes an excessively rapid rise in HR.
Patients in sinus rhythm with left ventricular ejection fraction ≤0.40 underwent MTWA exercise tests, analyzed with the spectral method and classified by a computerized interpretation algorithm. The primary end point was all-cause mortality or documented non-fatal sustained ventricular arrhythmia (SVA). “Indeterminate” tests were reviewed jointly by 2 readers blinded to subsequent events to determine the primary reason for indeterminacy.
Participants (N = 549) were 56 ± 13 years and 71% male; 49% had ischemic cardiomyopathy. There were 40 deaths and 11 non-fatal SVA. Most (94%) indeterminate results were due to patient factors. The 2-year rate for death or SVA was 17.8% in patients with an “indeterminate” MTWA test compared with 12.3% in those with a positive test.
In patients with left ventricular dysfunction, an “indeterminate” MTWA test due to patient factors predicted death or SVA at least as well as a positive test.</description><subject>Adult</subject><subject>Aged</subject><subject>Arrhythmias, Cardiac - etiology</subject><subject>Biological and medical sciences</subject><subject>Cardiac arrhythmia</subject><subject>Cardiac dysrhythmias</subject><subject>Cardiology</subject><subject>Cardiology. Vascular system</subject><subject>Electrophysiologic Techniques, Cardiac - methods</subject><subject>Exercise Test</subject><subject>Female</subject><subject>Heart</subject><subject>Heart attacks</subject><subject>Heart failure, cardiogenic pulmonary edema, cardiac enlargement</subject><subject>Heart Rate</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Mortality</subject><subject>Patients</subject><subject>Predictive Value of Tests</subject><subject>Prognosis</subject><subject>Risk Assessment</subject><subject>Ventricular Dysfunction, Left - complications</subject><subject>Ventricular Dysfunction, Left - mortality</subject><issn>0735-1097</issn><issn>1558-3597</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2006</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kcFu1DAQhi0EokvhBTggSwhuWezYThyJy6qltNIiKljo0XKcCeuQdVrbWWlvfZBy4dH6JDjalSo4II00h_nmH_v_EXpJyZwSWrzr5p02Zp4TUsyn4vwRmlEhZMZEVT5GM1IykVFSlUfoWQgdSaCk1VN0REtCiST5DP2-v727cA1E8BvrdIT721_4kzV-2A59xKvsSm8BL_o0d9oFvIIQA7700FgT8bn9scZfbPiJhxafgo5rPHj8dQxRWwcN_g4uemvGXnu88H69i-uN1QFbhy91tGka8JVNW0to41_06S60ozPRDu45etLqPsCLQz9G384-rE7Os-Xnjxcni2VmOC9jVkJbl4KKsmZtwxjoojC1MbJhlEJd6JwaqvNal0I0hkuat5xNbGEYF5Rpdoze7nWv_XAzpn-qjQ0G-l47GMagClnRnBGewNf_gN0wJnv6oKggBS2lYDJR-Z5KXobgoVXX3m603ylK1JSf6tSUn5ryU1PxSfrVQXqsN9A8rBwCS8CbA6CD0X3rtTM2PHCSFpJX0_X3ew6SY1sLXgWT_DYpNw8mqmaw_3vHH_3vvSM</recordid><startdate>20061003</startdate><enddate>20061003</enddate><creator>Kaufman, Elizabeth S.</creator><creator>Bloomfield, Daniel M.</creator><creator>Steinman, Richard C.</creator><creator>Namerow, Pearila B.</creator><creator>Costantini, Ottorino</creator><creator>Cohen, Richard J.</creator><creator>Bigger, J. Thomas</creator><general>Elsevier Inc</general><general>Elsevier Science</general><general>Elsevier Limited</general><scope>6I.</scope><scope>AAFTH</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7T5</scope><scope>7TK</scope><scope>H94</scope><scope>K9.</scope><scope>NAPCQ</scope><scope>7X8</scope></search><sort><creationdate>20061003</creationdate><title>“Indeterminate” Microvolt T-Wave Alternans Tests Predict High Risk of Death or Sustained Ventricular Arrhythmias in Patients With Left Ventricular Dysfunction</title><author>Kaufman, Elizabeth S. ; Bloomfield, Daniel M. ; Steinman, Richard C. ; Namerow, Pearila B. ; Costantini, Ottorino ; Cohen, Richard J. ; Bigger, J. Thomas</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c447t-7efb75157b3fd33ea66cbcc8d311eb6a21c1a2ba755dc4812f437b3f6c34513a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2006</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Arrhythmias, Cardiac - etiology</topic><topic>Biological and medical sciences</topic><topic>Cardiac arrhythmia</topic><topic>Cardiac dysrhythmias</topic><topic>Cardiology</topic><topic>Cardiology. Vascular system</topic><topic>Electrophysiologic Techniques, Cardiac - methods</topic><topic>Exercise Test</topic><topic>Female</topic><topic>Heart</topic><topic>Heart attacks</topic><topic>Heart failure, cardiogenic pulmonary edema, cardiac enlargement</topic><topic>Heart Rate</topic><topic>Humans</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Mortality</topic><topic>Patients</topic><topic>Predictive Value of Tests</topic><topic>Prognosis</topic><topic>Risk Assessment</topic><topic>Ventricular Dysfunction, Left - complications</topic><topic>Ventricular Dysfunction, Left - mortality</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kaufman, Elizabeth S.</creatorcontrib><creatorcontrib>Bloomfield, Daniel M.</creatorcontrib><creatorcontrib>Steinman, Richard C.</creatorcontrib><creatorcontrib>Namerow, Pearila B.</creatorcontrib><creatorcontrib>Costantini, Ottorino</creatorcontrib><creatorcontrib>Cohen, Richard J.</creatorcontrib><creatorcontrib>Bigger, J. Thomas</creatorcontrib><collection>ScienceDirect Open Access Titles</collection><collection>Elsevier:ScienceDirect:Open Access</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Immunology Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Premium</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of the American College of Cardiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kaufman, Elizabeth S.</au><au>Bloomfield, Daniel M.</au><au>Steinman, Richard C.</au><au>Namerow, Pearila B.</au><au>Costantini, Ottorino</au><au>Cohen, Richard J.</au><au>Bigger, J. Thomas</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>“Indeterminate” Microvolt T-Wave Alternans Tests Predict High Risk of Death or Sustained Ventricular Arrhythmias in Patients With Left Ventricular Dysfunction</atitle><jtitle>Journal of the American College of Cardiology</jtitle><addtitle>J Am Coll Cardiol</addtitle><date>2006-10-03</date><risdate>2006</risdate><volume>48</volume><issue>7</issue><spage>1399</spage><epage>1404</epage><pages>1399-1404</pages><issn>0735-1097</issn><eissn>1558-3597</eissn><coden>JACCDI</coden><abstract>“Indeterminate” Microvolt T-Wave Alternans Tests Predict High Risk of Death or Sustained Ventricular Arrhythmias in Patients With Left Ventricular Dysfunction
Elizabeth S. Kaufman, Daniel M. Bloomfield, Richard C. Steinman, Pearila B. Namerow, Ottorino Costantini, Richard J. Cohen, J. Thomas Bigger Jr
We performed a microvolt T-wave alternans (MTWA) exercise test in 549 patients with left ventricular ejection fraction ≤0.40 and followed them for 2 years. Among MTWA tests classified as “indeterminate,” 94% were so classified owing to ventricular ectopy, unsustained MTWA, or low exercise heart rate. Patients with an indeterminate MTWA test were at least as likely to die or experience a non-fatal sustained ventricular arrhythmia (SVA) as those with a positive test. Therefore, patients with indeterminate and positive MTWA tests can be combined into a single “abnormal” group at high risk of death or SVAs.
This study tested the hypothesis that an “indeterminate” microvolt T-wave alternans (MTWA) test, when due to ectopy, unsustained MTWA, or low exercise heart rate (HR), has prognostic significance similar to a positive MTWA test.
MTWA testing, used to stratify risk of sudden or total mortality in patients with structural heart disease, has been limited by a substantial number of “indeterminate” tests. Indeterminate tests are due to patient factors—excessive ventricular ectopy during exercise, unsustained MTWA, or failure to achieve a HR of 105 beats/min for 1 min—or technical factors such as a noisy recording or an exercise protocol that causes an excessively rapid rise in HR.
Patients in sinus rhythm with left ventricular ejection fraction ≤0.40 underwent MTWA exercise tests, analyzed with the spectral method and classified by a computerized interpretation algorithm. The primary end point was all-cause mortality or documented non-fatal sustained ventricular arrhythmia (SVA). “Indeterminate” tests were reviewed jointly by 2 readers blinded to subsequent events to determine the primary reason for indeterminacy.
Participants (N = 549) were 56 ± 13 years and 71% male; 49% had ischemic cardiomyopathy. There were 40 deaths and 11 non-fatal SVA. Most (94%) indeterminate results were due to patient factors. The 2-year rate for death or SVA was 17.8% in patients with an “indeterminate” MTWA test compared with 12.3% in those with a positive test.
In patients with left ventricular dysfunction, an “indeterminate” MTWA test due to patient factors predicted death or SVA at least as well as a positive test.</abstract><cop>New York, NY</cop><pub>Elsevier Inc</pub><pmid>17010802</pmid><doi>10.1016/j.jacc.2006.06.044</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0735-1097 |
| ispartof | Journal of the American College of Cardiology, 2006-10, Vol.48 (7), p.1399-1404 |
| issn | 0735-1097 1558-3597 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_68912304 |
| source | MEDLINE; Access via ScienceDirect (Elsevier); EZB-FREE-00999 freely available EZB journals; Alma/SFX Local Collection |
| subjects | Adult Aged Arrhythmias, Cardiac - etiology Biological and medical sciences Cardiac arrhythmia Cardiac dysrhythmias Cardiology Cardiology. Vascular system Electrophysiologic Techniques, Cardiac - methods Exercise Test Female Heart Heart attacks Heart failure, cardiogenic pulmonary edema, cardiac enlargement Heart Rate Humans Male Medical sciences Middle Aged Mortality Patients Predictive Value of Tests Prognosis Risk Assessment Ventricular Dysfunction, Left - complications Ventricular Dysfunction, Left - mortality |
| title | “Indeterminate” Microvolt T-Wave Alternans Tests Predict High Risk of Death or Sustained Ventricular Arrhythmias in Patients With Left Ventricular Dysfunction |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-11-29T10%3A37%3A43IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=%E2%80%9CIndeterminate%E2%80%9D%20Microvolt%20T-Wave%20Alternans%20Tests%20Predict%20High%20Risk%20of%20Death%20or%20Sustained%20Ventricular%20Arrhythmias%20in%20Patients%20With%20Left%20Ventricular%20Dysfunction&rft.jtitle=Journal%20of%20the%20American%20College%20of%20Cardiology&rft.au=Kaufman,%20Elizabeth%20S.&rft.date=2006-10-03&rft.volume=48&rft.issue=7&rft.spage=1399&rft.epage=1404&rft.pages=1399-1404&rft.issn=0735-1097&rft.eissn=1558-3597&rft.coden=JACCDI&rft_id=info:doi/10.1016/j.jacc.2006.06.044&rft_dat=%3Cproquest_cross%3E68912304%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1506178538&rft_id=info:pmid/17010802&rft_els_id=S0735109706017943&rfr_iscdi=true |