Combined Merkel cell carcinoma and atypical fibroxanthoma
Although there are reports of squamous cell carcinoma arising within and adjacent to Merkel cell carcinoma, and one report of an atypical fibroxanthoma-like tumor arising in an irradiated recurrent Merkel cell carcinoma, there have previously been no reports of an immunohistochemically verified atyp...
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Veröffentlicht in: | Journal of cutaneous medicine and surgery 2005-02, Vol.9 (1), p.6-9 |
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container_title | Journal of cutaneous medicine and surgery |
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creator | YOUKER, Summer R BILLINGSLEY, Elizabeth M |
description | Although there are reports of squamous cell carcinoma arising within and adjacent to Merkel cell carcinoma, and one report of an atypical fibroxanthoma-like tumor arising in an irradiated recurrent Merkel cell carcinoma, there have previously been no reports of an immunohistochemically verified atypical fibroxanthoma occurring in conjunction with a Merkel cell carcinoma.
We report on a neoplasm with distinct features of both Merkel cell carcinoma and atypical fibroxanthoma.
Histologic and immunohistochemical evaluations were performed.
Our results verify the finding of a combined Merkel cell carcinoma and atypical fibroxanthoma.
This case is an interesting and unusual combination of tumors. The origin of the Merkel cell carcinoma is revisited. Debated origins include neuroendocrine, epithelial, and pleuripotent stem cell. |
doi_str_mv | 10.1007/s10227-005-0024-4 |
format | Article |
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We report on a neoplasm with distinct features of both Merkel cell carcinoma and atypical fibroxanthoma.
Histologic and immunohistochemical evaluations were performed.
Our results verify the finding of a combined Merkel cell carcinoma and atypical fibroxanthoma.
This case is an interesting and unusual combination of tumors. The origin of the Merkel cell carcinoma is revisited. Debated origins include neuroendocrine, epithelial, and pleuripotent stem cell.</description><identifier>ISSN: 1203-4754</identifier><identifier>EISSN: 1615-7109</identifier><identifier>DOI: 10.1007/s10227-005-0024-4</identifier><identifier>PMID: 16208439</identifier><language>eng</language><publisher>Hamilton, ON: Decker</publisher><subject>Aged ; Aged, 80 and over ; Biological and medical sciences ; Carcinoma, Merkel Cell - diagnosis ; Carcinoma, Merkel Cell - therapy ; Dermatology ; Diagnosis, Differential ; Fatal Outcome ; Histiocytoma, Malignant Fibrous - diagnosis ; Histiocytoma, Malignant Fibrous - therapy ; Humans ; Immunohistochemistry ; Lip Neoplasms - diagnosis ; Lip Neoplasms - therapy ; Male ; Medical sciences</subject><ispartof>Journal of cutaneous medicine and surgery, 2005-02, Vol.9 (1), p.6-9</ispartof><rights>2006 INIST-CNRS</rights><rights>Canadian Dermatology Association 2005</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c356t-f02edc86747fd3d5d666ff8e5c5c73dd47e2f5820baab6d2fe1c31ec889b361e3</citedby><cites>FETCH-LOGICAL-c356t-f02edc86747fd3d5d666ff8e5c5c73dd47e2f5820baab6d2fe1c31ec889b361e3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27923,27924</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=17464773$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/16208439$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>YOUKER, Summer R</creatorcontrib><creatorcontrib>BILLINGSLEY, Elizabeth M</creatorcontrib><title>Combined Merkel cell carcinoma and atypical fibroxanthoma</title><title>Journal of cutaneous medicine and surgery</title><addtitle>J Cutan Med Surg</addtitle><description>Although there are reports of squamous cell carcinoma arising within and adjacent to Merkel cell carcinoma, and one report of an atypical fibroxanthoma-like tumor arising in an irradiated recurrent Merkel cell carcinoma, there have previously been no reports of an immunohistochemically verified atypical fibroxanthoma occurring in conjunction with a Merkel cell carcinoma.
We report on a neoplasm with distinct features of both Merkel cell carcinoma and atypical fibroxanthoma.
Histologic and immunohistochemical evaluations were performed.
Our results verify the finding of a combined Merkel cell carcinoma and atypical fibroxanthoma.
This case is an interesting and unusual combination of tumors. The origin of the Merkel cell carcinoma is revisited. Debated origins include neuroendocrine, epithelial, and pleuripotent stem cell.</description><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Biological and medical sciences</subject><subject>Carcinoma, Merkel Cell - diagnosis</subject><subject>Carcinoma, Merkel Cell - therapy</subject><subject>Dermatology</subject><subject>Diagnosis, Differential</subject><subject>Fatal Outcome</subject><subject>Histiocytoma, Malignant Fibrous - diagnosis</subject><subject>Histiocytoma, Malignant Fibrous - therapy</subject><subject>Humans</subject><subject>Immunohistochemistry</subject><subject>Lip Neoplasms - diagnosis</subject><subject>Lip Neoplasms - therapy</subject><subject>Male</subject><subject>Medical sciences</subject><issn>1203-4754</issn><issn>1615-7109</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2005</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpdkEtLw0AQgBdRbK3-AC8SBL1FZ_aZHKX4gooXPS-bfWBqk9TdFuy_d0sLBQ_zgPlmGD5CLhHuEEDdJwRKVQkgclBe8iMyRomiVAj1ce4psJIrwUfkLKU5ACAKfkpGKClUnNVjUk-Hrml774o3H7_9orB-kZOJtu2HzhSmd4VZbZatNYsitE0cfk2_-sqjc3ISzCL5i32dkM-nx4_pSzl7f36dPsxKy4RclQGod7aSiqvgmBNOShlC5YUVVjHnuPI0iIpCY0wjHQ0eLUNvq6pumETPJuR2d3cZh5-1TyvdtWn7pen9sE5aVjUiMJrB63_gfFjHPv-mKa0rDgxFhnAH2TikFH3Qy9h2Jm40gt5K1TupOkvVW6ma552r_eF103l32NhbzMDNHjApewrR9LZNB05xyZVi7A8kr35F</recordid><startdate>20050201</startdate><enddate>20050201</enddate><creator>YOUKER, Summer R</creator><creator>BILLINGSLEY, Elizabeth M</creator><general>Decker</general><general>SAGE PUBLICATIONS, INC</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>K9.</scope><scope>7X8</scope></search><sort><creationdate>20050201</creationdate><title>Combined Merkel cell carcinoma and atypical fibroxanthoma</title><author>YOUKER, Summer R ; BILLINGSLEY, Elizabeth M</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c356t-f02edc86747fd3d5d666ff8e5c5c73dd47e2f5820baab6d2fe1c31ec889b361e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2005</creationdate><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Biological and medical sciences</topic><topic>Carcinoma, Merkel Cell - diagnosis</topic><topic>Carcinoma, Merkel Cell - therapy</topic><topic>Dermatology</topic><topic>Diagnosis, Differential</topic><topic>Fatal Outcome</topic><topic>Histiocytoma, Malignant Fibrous - diagnosis</topic><topic>Histiocytoma, Malignant Fibrous - therapy</topic><topic>Humans</topic><topic>Immunohistochemistry</topic><topic>Lip Neoplasms - diagnosis</topic><topic>Lip Neoplasms - therapy</topic><topic>Male</topic><topic>Medical sciences</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>YOUKER, Summer R</creatorcontrib><creatorcontrib>BILLINGSLEY, Elizabeth M</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of cutaneous medicine and surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>YOUKER, Summer R</au><au>BILLINGSLEY, Elizabeth M</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Combined Merkel cell carcinoma and atypical fibroxanthoma</atitle><jtitle>Journal of cutaneous medicine and surgery</jtitle><addtitle>J Cutan Med Surg</addtitle><date>2005-02-01</date><risdate>2005</risdate><volume>9</volume><issue>1</issue><spage>6</spage><epage>9</epage><pages>6-9</pages><issn>1203-4754</issn><eissn>1615-7109</eissn><abstract>Although there are reports of squamous cell carcinoma arising within and adjacent to Merkel cell carcinoma, and one report of an atypical fibroxanthoma-like tumor arising in an irradiated recurrent Merkel cell carcinoma, there have previously been no reports of an immunohistochemically verified atypical fibroxanthoma occurring in conjunction with a Merkel cell carcinoma.
We report on a neoplasm with distinct features of both Merkel cell carcinoma and atypical fibroxanthoma.
Histologic and immunohistochemical evaluations were performed.
Our results verify the finding of a combined Merkel cell carcinoma and atypical fibroxanthoma.
This case is an interesting and unusual combination of tumors. The origin of the Merkel cell carcinoma is revisited. Debated origins include neuroendocrine, epithelial, and pleuripotent stem cell.</abstract><cop>Hamilton, ON</cop><pub>Decker</pub><pmid>16208439</pmid><doi>10.1007/s10227-005-0024-4</doi><tpages>4</tpages></addata></record> |
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source | MEDLINE; SAGE Complete A-Z List |
subjects | Aged Aged, 80 and over Biological and medical sciences Carcinoma, Merkel Cell - diagnosis Carcinoma, Merkel Cell - therapy Dermatology Diagnosis, Differential Fatal Outcome Histiocytoma, Malignant Fibrous - diagnosis Histiocytoma, Malignant Fibrous - therapy Humans Immunohistochemistry Lip Neoplasms - diagnosis Lip Neoplasms - therapy Male Medical sciences |
title | Combined Merkel cell carcinoma and atypical fibroxanthoma |
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