Mutation analysis of DARPP-32 as a candidate gene for schizophrenia

Dopamine- and cAMP-regulated phosphoprotein of relative molecular mass 32 kDa (DARPP-32) plays a pivotal role in the signal transduction of several neurotransmitters and neuromodulators that are implicated in the pathophysiology of a variety of neuropsychiatric disorders. A postmortem study reported...

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Veröffentlicht in:	Schizophrenia research 2006-10, Vol.87 (1), p.1-5
Hauptverfasser:	Li, Chen-Hao, Liao, Hsiao-Mei, Hung, Tsai-Wei, Chen, Chia-Hsiang
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult and adolescent clinical studies Alleles Binding Sites Biological and medical sciences Cyclic AMP - genetics Cyclic AMP - metabolism DARPP-32 DNA Fragmentation DNA Mutational Analysis - methods DNA Primers - genetics Dopamine and cAMP-Regulated Phosphoprotein 32 - genetics Etiology Exons - genetics Female Genetic Predisposition to Disease Genetics Genotype Humans Inteins - genetics Male Medical sciences Middle Aged Mutation Point Mutation - genetics Polymerase Chain Reaction Polymorphism, Single Nucleotide - genetics Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry Psychoses Schizophrenia Schizophrenia - genetics Schizophrenia - metabolism Schizophrenia - physiopathology Susceptibility Transcriptional Activation - genetics
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