Superoxide dismutase activity in colostrum, transitional and mature human milk

Colostrum and mature human milk are rich sources of nutrients and contain biologically active molecules that are essential for specific antioxidant functions. The aim of the present study was to determine the activity of copper, zinc superoxide dismutase (CuZnSOD) and manganese superoxide dismutase...

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Veröffentlicht in:Turkish journal of pediatrics 2005-10, Vol.47 (4), p.343-347
Hauptverfasser: Kasapović, Jelena, Pejić, Snezana, Mladenović, Marija, Radlović, Nedeljko, Pajović, Snezana B
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container_issue 4
container_start_page 343
container_title Turkish journal of pediatrics
container_volume 47
creator Kasapović, Jelena
Pejić, Snezana
Mladenović, Marija
Radlović, Nedeljko
Pajović, Snezana B
description Colostrum and mature human milk are rich sources of nutrients and contain biologically active molecules that are essential for specific antioxidant functions. The aim of the present study was to determine the activity of copper, zinc superoxide dismutase (CuZnSOD) and manganese superoxide dismutase (MnSOD) activity in different phases of lactation. Specific enzyme activity was determined in colostral milk (3rd-5th days after delivery), and in mature milk in the third week (15-20 days), and the fourth and seventh months of lactation. In the third week of lactation, the activity of CuZnSOD and MnSOD was significantly higher in comparison to the colostral phase. In the fourth month of lactation, the activity of both enzymes was suppressed, while in the seventh month of lactation the MnSOD activity was increased, and the CuZnSOD activity was not significantly changed. These findings show that the activities of superoxide dismutases significantly change during different phases of lactation.
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The aim of the present study was to determine the activity of copper, zinc superoxide dismutase (CuZnSOD) and manganese superoxide dismutase (MnSOD) activity in different phases of lactation. Specific enzyme activity was determined in colostral milk (3rd-5th days after delivery), and in mature milk in the third week (15-20 days), and the fourth and seventh months of lactation. In the third week of lactation, the activity of CuZnSOD and MnSOD was significantly higher in comparison to the colostral phase. In the fourth month of lactation, the activity of both enzymes was suppressed, while in the seventh month of lactation the MnSOD activity was increased, and the CuZnSOD activity was not significantly changed. 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subjects Adult
Colostrum - enzymology
Female
Humans
Lactation - physiology
Milk, Human - enzymology
Superoxide Dismutase - metabolism
Time Factors
title Superoxide dismutase activity in colostrum, transitional and mature human milk
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